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Neuron Signaling in Metabolic Regulation (Methods in Signal Transduction Series)
By Qingchun Tong. 2020
This book focuses on neuron signaling in the regulation of metabolism and body weight, and especially on methods used in…
these studies. Obesity and related metabolic syndromes have reached epidemic status, but still are no effective strategies for prevention and treatment. Body weight homeostasis is maintained by balanced food intake and energy expenditure, both of which are under the control of brain neurons. In the recent years, significant progress has been made in identifying specific neurons, neural pathways, and non-neuron cells in feeding regulation, as well as in delineating autonomic nervous systems targeting peripheral metabolic tissues in the regulation of energy expenditure and metabolism. This book reviews recent progress on important neuron signaling for body weight and metabolic regulation and the state-of-the-art methods that has been applied in this field, ranging from animal models with neuron-specific manipulations, pharmacology, optogenetics, in vivo Ca2+ imaging, and viral tracing. Readers will be exposed to latest research frontiers on neuron regulation of metabolism. Key Features Explores the role signaling between neurons plays with respect to metabolism Documents how neurotransmitters affect the regulation of feeding Describes various methods and technologies used to study the neuronal control of metabolism Includes contributions from an international team of leading researchers. Related Titles Lim, W. & B. Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1) Feltz, A. Physiology of Neurons (ISBN 978-0-8153-4600-5) Zempleni, J. & K. Dakshinamurti, eds. Nutrients and Cell Signaling (ISBN 978-0367-39307-6)Health Equity in Hospital Medicine: Foundations, Populations, and Action
By Sujatha Sankaran. 2023
Hospital-based physicians are privy to some of the most meaningful moments of people’s lives, including life-changing diagnoses, pivotal medical procedures,…
complex medical decisions, and critical end-of-life decisions. Yet, hospitalists have no framework for how to incorporate the varied social factors that impact care such as race, gender identity, cultural background, immigration status, sexual orientation, primary language, housing status, and poverty into clinical decision-making. As hospital physicians, we may use interpreters for our limited English proficiency patients, or try to incorporate questions about cultural practices into our admission histories, or even ask our patients about the ways in which they feel racism has affected their care, but these practices are inconsistently applied and lack a systematic framework for ensuring that the hospital care we provide is truly equitable. In my own practice as a hospital-based physician, I can recall scores of hospitalized patients where we tried hard to provide equitable care, but fell short. I remember the Spanish-speaking patient with multiple comorbidities who received neurosurgery and was on the road to recovery on an acute care unit, when on day three, he complained of vague abdominal discomfort and ended up dying of a perforated bowel. No interpreter was used by the team to fully delve into the details of the pain he was experiencing. I remember the young Black patient with terminal malignancy who had multiple repeated conversations with physicians recommending hospice care but refused until he saw a physician who was able to explain hospice within the context of racism that has historically defined clinical care for Black people, and was able to present hospice not as a way to hasten death but rather as a way to live the remainder of his days in comfort. I remember the elderly Pakistani female patient whose demanding son antagonized staff and clinicians alike until he was banned from visiting because of his aggressiveness with staff and whose inability to visit his mother caused her extreme distress as she felt that she had lost the unique voice that only her oldest son could provide. Imagine if the hospital physicians in these cases had a resource to help them provide care that is culturally humble, that goes beyond just speaking in the patient’s first language but that also includes active listening and truly takes into consideration the life experiences and culture that have made this patient who they are. This is what this book will provide for hospital medicine physicians, a framework to help hospital physicians deeply incorporate social factors into the care they provide.The Long Case OSCE: The Ultimate Guide for Medical Students
By Beth Walker, Marsha Morgan. 2013
A solid knowledge base and good clinical skills don’t necessarily guarantee examination success in the long case OSCE. This book…
is the ultimate guide for medical students needing to combine their knowledge and skills with an ability to interpret the clinical findings, the proficiency to present them clearly and the confidence to deal with the examiners questions. Adopting a proven, highly effective approach, this revision aid uses role play with simulated patients to hone clinical examination and presentation skills. The fifty cases are divided into six areas: cardiology, respiratory, abdomen, neurology, musculoskeletal and surgery. Written by successful candidates and examiners, the guide poses a number of important and commonly asked examination questions for each case to assist in preparation and confidence, and model answers are provided to ensure an understanding of exactly what is required. Working in groups or independently, students will welcome the large, colourful format, the breakdown of marking schemes, an overview of examiners expectations, a guide to presenting clinical findings and innumerable ‘insider’ tips throughout. See accompanying video here: https://www.youtube.com/watch?v=Cvr4y-NykUUEndocrinology: Pathophysiology to Therapy
By Akuffo Quarde. 2024
Endocrinology Enables readers to form an integrated understanding of endocrine physiology by examining the mechanisms of action of medical therapies…
Endocrinology: Pathophysiology to Therapy is a comprehensive resource on medical therapies; in each chapter, the relevant endocrine physiology of the medical therapy is presented, followed by a review of the detailed mechanism of action of selected medical interventions. Where applicable, emphasis is placed on clinical pharmacology pearls, such as side effects and therapeutic monitoring guidelines. Supplementary chapters address additional topics, including immune checkpoint inhibitor-related endocrinopathies, anabolic steroid abuse, pseudo-endocrine conditions, and dynamic tests in clinical endocrinology. Rather than emphasizing guideline-defined treatment protocols, this??book directs attention towards the pathophysiology and fundamental principles of endocrine therapies. Categories of therapies covered in Endocrinology include: Pituitary gland therapies, including Cushing’s disease, Acromegaly, Prolactinoma, adult growth hormone insufficiency, central diabetes insipidus, and syndrome of inappropriate ADH secretion Thyroid gland therapies, including Hashimoto’s thyroiditis, Graves’ Disease, Thyroid Eye Disease, Riedel’s thyroiditis, Thyroid hormone resistance, and RSH secreting tumors Adrenal gland therapies, including primary adrenal insufficiency, primary hyperaldosteronism, classic congenital adrenal hyperplasia, and nonclassic congenital adrenal hyperplasia Pancreatic gland therapies, including diabetes mellitus, neuroendocrine tumors, and hypoglycemia syndromes such as somatostatin analogs and calcium channel blockers Discussing the rationale for using various therapies and enabling readers to appreciate complex concepts in a clinically relevant manner, Endocrinology is an essential reference for practitioners in related fields looking for an accessible and comprehensive resource on the subject.Klinische Endokrinologie für Frauenärzte
By Freimut A. Leidenberger, Thomas Strowitzki and Olaf Ortmann. 2014
Durch eine grundlegende und intensive Bearbeitung für die 5. Auflage wurde der „Klassiker“ noch einmal besser an die Bedürfnisse des…
Lesers angepasst, ohne jedoch auf bewährte Inhalte und Elemente zu verzichten.NEU - Neustrukturierung und -zusammenstellung der Themen und Kapitel - Kapitel zu Normalfunktion und gestörter Funktion stehen direkt beieinander, so entfällt mühsames Blättern bei Nachlesen- Multiple-Choice-Fragenkatalog - Online verfügbar: Qualitativ hochwertige und aktuelle Literaturverzeichnisse BEWÄHRT- Berücksichtigung nationaler und internationaler Leitlinien - Mit Testfragen zur Selbstkontrolle- Zusammenfassungen am Ende jedes Kapitels VERLÄSSLICH- Aktuelles Wissen, leicht verständlich- Praxisrelevante Darstellung aller wichtigen Aspekte des Fachs- Berücksichtigung innovativer Ansätze„Klinische Endokrinologie für Frauenärzte“ - Das Standardwerk mit einer Fülle an täglich anwendbarem Wissen!Treatment of the Obese Patient
By Robert F. Kushner and Daniel H. Bessesen. 2014
This is a timely and informative updated edition for all health care providers challenged with helping patients manage weight. Similar to…
the well-reviewed first edition, this updated title is directed toward individuals who wish to read further about targeted topics, rather than find an introduction to the field. This second edition again provides insights into recent scientific advances in obesity research and provides the most up-to-date instruction about current treatment issues and strategies for both adults and children. While several of the chapters are no longer relevant from the first edition, other topics have emerged as interesting and current. This edition will keep the two-section format of Physiology and Pathophysiology and Clinical Management, but it increases the first section to 10 chapters and reduces the second section to 12 chapters. The plan is to keep this edition in the range of about 350 to 400, maximum, printed pages. The volume is again divided into two parts. Part 1 covers new discoveries in the physiological control of body weight, as well as the pathophysiology of obesity. Expert authors discuss pathways that control food intake, energy expenditure and peripheral nutrient metabolism, including a look at the emerging evidence of the role of adipose tissue as an endocrine organ. Part 2 covers all the key issues central to clinical management, including recent developments in the epidemiology of obesity, assessment of the obese patient, behavioral strategies in weight management, dietary modification as a weight management strategy, physical activity as a weight management strategy, weight loss drugs, surgical approaches to obesity and other important clinical topics. An essential, practical text that sorts, synthesizes and interprets the latest information on obesity-related topics, this second edition will be an essential resource for clinical endocrinologists and other health care providers across a broad spectrum of specialties.The Diabetes Breakthrough: Based on a Scientifically Proven Plan to Lose Weight and Cut Medications
By Osama Hamdy, Sheri Colberg. 2015
A Harvard Medical School diabetes specialist and a top exercise physiologist share a proven and effective 12-week plan to reverse…
the course of Type 2 diabetes, lose weight, and ditch the medication for good.In this groundbreaking book, diabetes and weight management expert Osama Hamdy, M.D., Ph.D., reveals how you can reverse the course of your type 2 diabetes, lose weight for good and finally reclaim your health—in just 12 weeks! This book will help you: Cut your medications by 50-60%—or even stop them altogether! Learn how to safely lose—and keep off—those 10, 20 or even 50 plus pounds that are holding you back from a healthy life. Tailor your exercise plan to the way you really live and work, so you can get results without being a slave to the gym. …and more!With information on how to create checklists, goal worksheets, and including real-life success stories, The Diabetes Breakthrough will help keep you motivated in making smart decisions—even on the busiest days!An eye-opening investigation into the history of diabetes research and treatment by the award-winning journalist and best-selling author of Why…
We Get Fat • "[Gary] Taubes&’s meticulous, science-based work makes him the Bryan Stevenson of nutrition, an early voice in the wilderness for an unorthodox view that is increasingly becoming accepted."—Niel Barsky, The GuardianBefore the discovery of insulin, diabetes was treated almost exclusively through diet, from subsistence on meat, to reliance on fats, to repeated fasting and near-starvation regimens. After two centuries of conflicting medical advice, most authorities today believe that those with diabetes can have the same dietary freedom enjoyed by the rest of us, leaving the job of controlling their disease to insulin therapy and other blood-sugar-lowering medications. Rather than embark on &“futile&” efforts to restrict sugar or carbohydrate intake, people with diabetes can lead a normal life, complete with the occasional ice-cream cake, side of fries, or soda.These guiding principles, however, have been accompanied by an explosive rise in diabetes over the last fifty years, particularly among underserved populations. And the health of those with diabetes is expected to continue to deteriorate inexorably over time, with ever-increasing financial, physical, and psychological burdens. In Rethinking Diabetes, Gary Taubes explores the history underpinning the treatment of diabetes, types 1 and 2, elucidating how decades-old research that is rife with misconceptions has continued to influence the guidance physicians offer—at the expense of their patients&’ long-term well-being.The result of Taubes&’s work is a reimagining of diabetes care that argues for a recentering of diet—particularly, fewer carbohydrates and more fat—over a reliance on insulin. Taubes argues critically and passionately that doctors and medical researchers should question the established wisdom that may have enabled the current epidemic of diabetes and obesity, and renew their focus on clinical trials to resolve controversies that are now a century in the making.Life Without Diabetes: The definitive guide to understanding and reversing your type 2 diabetes
By Professor Roy Taylor. 2019
FOLLOW THIS REVOLUTIONARY HEALTH PLAN AND TRANSFORM YOUR LIFE... THIS PROGRAMME IS NOW BEING PILOTED ON THE NHSFrom the pioneer…
of diabetes reversal whose research is behind the new NHS programme to reverse type 2 diabetesProf Roy Taylor is one of the world's leading experts in type 2 diabetes, the man who discovered that this life-limiting disease was actually a reversible condition.With his team of researchers at Newcastle University, he launched a series of studies culminating in a multi-million-pound trial, which recently confirmed that simple advice about diet could bring about lasting remission.In Life Without Diabetes, Taylor brings all the knowledge and experience of four decades of treating people with diabetes. He explains exactly what is happening in the body as type 2 develops and presents a brilliant 3-step weight loss plan that will enable you to reverse your type 2 and live a full and healthy life beyond it.** Includes delicious tried-and-tested recipes **FROM THE CREATOR OF THE INTERNATIONAL BESTSELLING 5:2, A SIMPLE, FLEXIBLE NEW WEIGHT LOSS PROGRAMME BASED ON GROUNDBREAKING SCIENCE'The most…
eagerly awaited health book of the year.' Daily MailDr Michael Mosley started a health revolution with The 5.2 Fast Diet, telling the world about the incredible power of intermittent fasting. In this book he brings together all the latest science - including a new approach: Time Restricted Eating - to create an easy-to-follow programme.Recent studies have shown that 800 calories is the magic number when it comes to successful dieting - it's an amount high enough to be manageable but low enough to speed weight loss and trigger a range of desirable metabolic changes. The secret of this new programme is that it is highly flexible - depending on your goals, you can choose how intensively you want to do it.Along with delicious, low-carb, Mediterranean-style recipes and menu plans by Dr Clare Bailey, The Fast 800 offers an effective way to help you lose weight, improve mood and reduce blood pressure, inflammation and blood sugars. Take your future health into your own hands.Textbook of Diabetes
By RICHARD I.G. HOLT, Allan Flyvbjerg. 2024
Textbook of Diabetes Classic textbook providing diabetologists and endocrinologists with illustrated and clinically focused content on diabetes Now in its…
sixth edition, the Textbook of Diabetes has established itself as the modern, international guide to diabetes. Sensibly organized and easy to navigate, with exceptional illustrations, the textbook hosts an unrivalled blend of clinical and scientific content. Written by highly experienced editors and international contributors all of whom have provided insight on new developments in diabetes care. These include the most recent guidelines from the European Association for the Study of Diabetes (EASD), the American Diabetes Association (ADA), Diabetes UK, and the National Institute for Health and Care Excellence (NICE) and information on the latest treatment modalities used around the world. The textbook includes free access to the Wiley Digital Edition which provides easy-to-use searching across the book, the full reference list with web links, illustrations and photographs, and post-publication updates. Sample topics covered in Textbook of Diabetes include: Diabetes in its historical and social context, covering the history of diabetes, past classification and diagnosis of diabetes and the global burden of diabetes Normal physiology, covering glucose homeostasis, islet function and insulin secretion, and glucagon in islet and metabolic regulation Pathogenesis of diabetes, covering genetics of diabetes and obesity, autoimmune type 1 diabetes and other disorders with type 1 diabetes phenotype Other types of diabetes, covering endocrine disorders that cause diabetes, pancreatic diseases and diabetes and drug-induced diabetes Beautifully illustrated with a clinical focus, Textbook of Diabetes provides endocrinologists and diabetologists, both consultants/specialists and those in training, with a fresh and comprehensive clinical resource to consult time and time again. The text is also of value to specialist diabetes nurses and researchers in the field.Kickass Healthy LADA: How to Thrive with Latent Autoimmune Diabetes in Adults
By Jacqueline Haskins. 2023
The award-winning first book for the general public on LADA (Latent Auto-immune Diabetes in Adults), endorsed by a former president…
of the American Diabetes Association, Kickass Healthy LADA is a fun, empathetic, and practical guide brimming with insights and inspiration. If you are one of the millions of Americans with Latent Autoimmune Diabetes in Adults (LADA), you may not even know it. You may be one of the ten percent of people diagnosed with type 2 diabetes who actually have LADA. Even if you do know that you have LADA, sometimes called &“diabetes 1.5,&” you&’re likely to be inundated with unhelpful advice and potentially harmful treatments, leaving you feeling confused and overwhelmed. That was Jacqueline Haskins&’ experience. After visiting five doctors before getting helpful guidance, and realizing there wasn&’t a friendly &“how-to&” book meant for the general public about LADA—she decided to write one. Winner of the 2023 American BookFest Award in Health and a 2023 Reader&’s Favorite Five-Star selection, Kickass Healthy LADA is a welcoming, supportive book packed with practical strategies and tips that can be tailored to any lifestyle or heritage. This medically vetted go-to guide offers patients and their loved ones relief, hope, and critical information including: A detailed breakdown of the different diabetes diagnoses What makes LADA different and how to find the best treatment team Insulin: what it is, what it does, and how to know if we need more of this natural hormone Tools for good health with LADA, including food and nutrition advice Introducing Carb-Craft: how to safely enjoy the foods you love With a biologist&’s keen eye, a patient-advocate&’s tenacity, and the humor of a trusted friend, Jacqueline offers an essential toolkit for anyone diagnosed with LADA.Thyroid Disease in Pregnancy - A Guide to Clinical Management
By Haritha Sagili, Jayaprakash Sahoo, Swaramya Chandrasekaran. 2023
This book focuses on all aspects of thyroid disease in women during pregnancy, preconception and the postpartum period. Exceptional emphasis…
is provided on screening for thyroid dysfunction before and during pregnancy and interpretation of thyroid function tests in pregnancy. The chapters cover the topics on the role of Iodine, thyroid autoantibodies, hypothyroidism , thyrotoxicosis and thyroid nodules / cancer in pregnant women and postpartum thyroiditis with helpful illustrations and clear flow charts. This book serves as a resourceful guide for clinicians and medical practitioners in managing thyroid disease and related complications in women at different stages of pregnancy.Take Charge of Your Thyroid Disorder: Learn What's Causing Your Hashimoto's Thyroiditis, Grave's Disease, Goiters, or (Take Charge)
By Dr Alan Christianson, Hy Bender. 2020
Restore your thyroid balance with this no-nonsense informationUnusual fatigue, unexplained weight loss or gain, a racing heart, confusion, tremors, anxiety…
and depression, hair loss ... an ailing thyroid can cause any combination of these symptoms or dozens of others, making it difficult for even experienced doctors to recognize when you have a thyroid disorder. Learn the ins and outs of Hashimoto's Thyroiditis, Grave's Disease, goiters, and thyroid nodules, among other thyroid ailments. Millions of people live with thyroid disorders, detected and undetected. The next best thing to a personal thyroid specialist, this invaluable guide helps you navigate the maze of conflicting information and determine your best course of action.This guide will help you find the answers you're looking for. Within these pages, you'll find in-depth looks at thyroids, how they work and how they can go bad, advice on finding the perfect doctor and reaching a diagnosis, guidance on dealing with other thyroid-related issues such as thyroid cancer and adrenal gland disease, and even tips for living a healthy lifestyle, regardless of the setbacks. Discover the path toward a healthy thyroid and start your journey today!The rapid emergence of Type 2 diabetes has become one of the most urgent health issues facing not only Americans,…
but people around the globe. For those suffering from diabetes, managing the disease is a delicate and often confusing balancing act that is highly unpredictable and can be, at times, life-threatening. Effective diabetes management requires not only daily effort, but knowledge in order to control side effects. However, armed with that essential knowledge, diabetes sufferers can lead normal and healthy lives, with minimal issues. The Complete Idiot's Guide® to Managing Diabetes Fast-Track gives you critical yet practical insight to help manage the disease and minimize the risks. You will learn how to manage daily diet choices, as well long-term dietary habits so the illness doesn't progress. You will also learn the simple lifestyle changes that can make a huge difference and take your health from suffering to thriving. Helpful advice for managing medications and keeping diabetes in check when diet and exercise aren't enough is included so you are armed with the tools and practical guidance they need to lead a normal, healthy life.The Complete Idiot's Guide to Glycemic Index Weight Loss, 2nd Edition
By Joan Clark-Warner, Lucy Beale. 2010
A fully updated and expanded edition of a weight loss program that readers can count on This fully updated and…
expanded edition clearly explains just how and why a glycemic index diet works by showing readers how to eat the right kind of foods—more complex carbohydrates, fiber, grains, and fruit. • The glycemic index diet is a solution for many people at risk for Type II diabetes or those with insulin-sensitivity or resistance • Includes information on supplements, easy recipes, food lists, and sample meal plans • Includes an appendix with glycemic index counts and loads for all sorts of food • Features a new study on how eating certain foods cold can make a big differenceGut Microbiome, Microbial Metabolites and Cardiometabolic Risk (Endocrinology)
By Massimo Federici, Rossella Menghini. 2024
This reference work is strong informative about the role of the gut microbiome in organism metabolism and fully discusses the…
relationship between gut alterations and/or gut microbiome-derived metabolites and the pathogenesis of many diseases, as well as recent advances in clinical applications of microbiome and microbial effector molecules.It clearly shows how the microbiome research is a growing field in molecular and clinical sciences, due to technical advances based on high throughput genetic sequencing technologies and omics analyses that empower systems biology-based methods for precision health monitoring and treatment. It will help in understanding that high diversity of the microbial communities in the gut is important to preserve health and microbiome alterations, not only in nutrition associated diseases like obesity and diabetes, but also in many chronic inflammatory, cardiovascular, oncological and neurological disorders. Written by renown experts in the field, this reference work is intended for clinicians, residents, specialists and physicians involved in the diagnosis and treatment of affected patients. It is published as part of the SpringerReference program, which provides access to live editions constantly updated through a dynamic peer-review publishing process.Overcoming Type 2 Diabetes (Idiot's Guides)
By Carrie S. Swift. 2015
Approximately 29 million Americans have Type 2 Diabetes, and the numbers keep rising. Idiot's Guides: Overcoming Type 2 Diabetes provides…
comprehensive information on everything someone with this condition needs to know. A detailed, yet positive, discussion about diabetes, content includes symptoms, monitoring, medications, and support. Helpful advice on exercise and meal planning is also included.The Complete Idiot's Guide Glycemic Index Cookbook: More Than 300 Delicious Recipes for a Better Weight—and a Better You
By Joan Clark-Warner, Lucy Beale. 2009
Cook these recipes up-and keep blood sugar down. With over 325 delicious and healthy recipes, The Complete Idiot's Guide® to…
the Glycemic Index Cookbook is an invaluable reference for choosing foods according to their GI-a system of classifying carbohydrate-based foods by how much they raise blood sugar. Diabetes, insulin resistance, heart disease, and obesity may be avoided by following the glycemic index. Practical and easy to use, this is the one cookbook anyone concerned with their blood sugar will want to have in the kitchen.• More than 325 recipes • Includes both the GI value and a GL (glycemic load) rating for each recipe • 18 million people in the U.S. have type 2 diabetes and the number is growingHead and Neck Surgery for General Surgeons
By Bruce Ashford. 2023
General surgery is the common ancestor of all surgical specialties. Within general surgery, many subspecialty areas of practice have evolved. This book is…
the first manual recognizing the growing role General Surgeons play in Head & Neck Surgery. From benign to malignant conditions and form ablative to reconstructive challenges, the renowned comprehensive capability of the General Surgeon is well suited to demands of this discipline. Each chapter details relevant anatomical considerations to enable understanding of this complex regional specialty and the full range of head and neck pathologies with requisite assessment, investigation, surgical and relevant reconstructive techniques. Written by a multidisciplinary, international team of recognized experts, this textbook is a practical but comprehensive guide for both candidates preparing for final surgery examinations as well as general surgeons requiring an up-to-date source of definitive advice on topics of this regional specialty.