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Showing 921 - 940 of 3065 items
By Pawan K. Maurya, Kamal Dua. 2020
This book illustrates the importance and significance of oxidative stress in the pathophysiology of various human diseases. The book initially…
introduces the phenomenon of oxidative stress, basic chemical characteristics of the species involved and summarizes the cellular oxidant and anti-oxidant system and the cellular effects and metabolism of the oxidative stress. In addition, it reviews the current understanding of the potential impact of oxidative stress on telomere shortening, aging, and age-related diseases. It also examines the role of oxidative stress in chronic diseases, including cancer, diabetes, cardiovascular diseases, and neurodegenerative disorders. Further, the book presents novel technologies for the detection of oxidative stress biomarkers using nanostructure biosensors, as well as in vitro and in vivo models to monitor oxidative stress. Lastly, the book addresses the drug delivery carriers that can help in combating oxidative stress.By Madan Laxman Kapre. 2020
This book will bridge a gap between the huge platform of literature available about thyroid surgery and the practical working…
reality. The pearls in techniques and surgical procedures will be exhaustively detailed with authors' individual experience enriched with quality photographs. It covers management of large/massive multinodular goiters which are the hall mark of Indian Thyroids. However, the emphasis will be more on applying this knowledge to a given patient and would largely revolve around this theme. It aims to provide a take home message in controversial areas and is a ready reference to all interested in learning science and craftsmanship of thyroid surgery. Key Features Covers all topics comprehensively with a practical approach Inclusion of guidelines adds value to the content Discusses all investigatory modalities Consists of useful surgical tips with exhaustive operating photography Features large anatomical illustrations with cadaveric dissectionsBy Luca Giovanella, Giorgio Treglia. 2020
This open access book summarizes the findings of recent evidence-based articles (meta-analyses) on the use of positron emission tomography (PET)…
for various clinical indications. It is divided into five main sections, starting with an introduction to PET and meta-analysis. In turn, the second part addresses evidence-based PET in oncology, providing a broad overview of its use for different types of tumours. The remaining sections are focused on the use of PET in cardiology, in infectious and inflammatory diseases, and in neurology, respectively. Given its scope and the wealth of information it provides, the book will be an invaluable tool for clinicians with various specialties, as well as international scientific societies interested to the recent evidence-based data about PET.By Nidhi Gupta, Hemanshu Prabhakar. 2020
This book discusses normal brain physiology and renal physiology, as well as the interactions between the two. The physiology of…
the brain can easily be affected by any changes to the physiology of other systems, which in turn may compromise cerebral blood flow and oxygenation. Together the brain and the renal system help our body systems to function automatically. The book addresses the basic aspects of neurophysiology and renal physiology in three broad sections, the first of which covers the basic principles of cerebral physiology and neural regulation of the renal system. The second part reviews the normal physiology of the renal system, including the mechanism of action, while the last section summarizes the correlation between the brain and kidney. Highly informative and clearly structured, the book provides essential insights for anyone with an interest in physiology and medicine.By Rod Michalko. 1999
By Gareth Leng. 2018
How hormonal signals in one small structure of the brain—the hypothalamus—govern our physiology and behavior.As human beings, we prefer to…
think of ourselves as reasonable. But how much of what we do is really governed by reason? In this book, Gareth Leng considers the extent to which one small structure of the neuroendocrine brain—the hypothalamus—influences what we do, how we love, and who we are.The hypothalamus contains a large variety of neurons. These communicate not only through neurotransmitters, but also through peptide signals that act as hormones within the brain. While neurotransmitter signals tend to be ephemeral and confined by anatomical connectivity, the hormone signals that hypothalamic neurons generate are potent, wide-reaching, and long-lasting. Leng explores the evolutionary origins of these remarkable neurons, and where the receptors for their hormone signals are found in the brain. By asking how the hypothalamic neurons and their receptors are regulated, he explores how the hypothalamus links our passions with our reason. The Heart of the Brain shows in an accessible way how this very small structure is very much at the heart of what makes us human.By Margaret Conrad. 2020
At the Ocean’s Edge offers a vibrant account of Nova Scotia’s colonial history, situating it in an early and dramatic…
chapter in the expansion of Europe. Between 1450 and 1850, various processes – sometimes violent, often judicial, rarely conclusive – transferred power first from Indigenous societies to the French and British empires, and then to European settlers and their descendants who claimed the land as their own. This book not only brings Nova Scotia’s struggles into sharp focus but also unpacks the intellectual and social values that took root in the region. By the time that Nova Scotia became a province of the Dominion of Canada in 1867, its multicultural peoples, including Mi’kmaq, Acadian, African, and British, had come to a grudging, unequal, and often contested accommodation among themselves. Written in accessible and spirited prose, the narrative follows larger trends through the experiences of colourful individuals who grappled with expulsion, genocide, and war to establish the institutions, relationships, and values that still shape Nova Scotia’s identity.By Fanny J. Crosby. 2008
The memoirs and observations of the composer of over eight thousand hymns. Stories from her entire life from her blindness…
as an infant through her old age. Fanny Crosby was friends with famous people the world over including several presidents. She tells her story with love and compassion.By Stephen W. Carmichael. 1989
This volume provides a complete review of all the articles which have appeared in the literature since 1986 that pertain…
to the adrenal medulla and adrenal chromaffin. Over 1700 articles are reviewed, organized, and summarized. Topics covered include the transplantation of medulla into the brain, stimulus-secretion coupling, neuropeptides, enzymes of catecholamine biosynthesis, growth factors, neural regulation and clinical considerations, including imaging and tumors. This book will provide interesting reading for neurobiologists, cell biologists, pathologists, diagnostic radiologists, and advanced biology students.By George S. Eisenbarth. 1989
This important text will be the first devoted to a detailed analysis of immunotherapy as it applies to Type I…
diabetes and the pathogenesis and therapy of other specific autoimmune diseases (including uveitis, multiple sclerosis, myasthenia gravis, Cogan's syndrome, Graves' ophthalmopathy, and gonadal disorders).By Marek P. Dabrowski, B. Dabrowska-Bernstein. 1990
First published in 1990. This important new text covers a wide area of thymology in both the theoretical and practical…
aspects. In view of current information, a crucial role of endocrine thymus is presented in the creation, maintenance, and senescence of neuro-endocrine-immune homeostasis. In particular, mechanisms are described (which are basically responsible for the T cell maturation and selection) for the hierarchic organization of the immune system and its thymic dependent immune competence in terms of tolerance and immunity. A detailed presentation of the structure and biological properties of a number of well-defined thymic hormones is included. Their clinical applications and results obtained in inherited or acquired immunodeficiencies and in neoplasmic diseases are also reviewed on the grounds of numerous representative clinical trials. A perspective and potential scope of immunorestorative therapy and prevention with thymic hormones and other thymomimetic drugs are outlined. Researchers, practitioners, and students will find this book to be a useful and essential source of information.By Nathan F. Cardarelli. 1989
First published in 1989: This text was written to provide a relatively broad comprehensive study of the thymus in health…
and disease, including relationships to the endocrine system, immue system, and again.By Elisabeth Gitter. 2001
Did you ever wonder what inspired Helen Keller's mother to have such high hopes for her daughter? The answer is…
Laura Bridgman, the original deaf-blind girl who inspired Charles Darwin to visit her and also write about her in American Notes.By Gill Rumsby, Sheelagh M. Farrow. 1997
This volume in the Human Molecular Genetics series is an invaluable text for endocrinologists wishing to update their knowledge. It…
also provides an excellent grounding in the basic genetics of molecular endocrinology and relevant analytical techniques.By Derek H. Burney, Fen Osler Hampson. 2020
The world is changing - geopolitically and economically - at an alarmingly fast pace. Populism, protectionism, and authoritarianism are on…
the rise. Braver Canada analyzes these and many other global shifts, offering provocative prescriptions for both the public and the private sectors. Reviewing the foreign policy challenges, achievements, and missteps of the Justin Trudeau government, Derek Burney and Fen Hampson argue that the country's leadership must craft a new approach to global affairs based on a solid grasp of current and emerging global political and economic realities. They focus on competitiveness, trade, energy, environment, and immigration and refugee issues, also discussing a recalibration of relations with China and India. Expanding on the ideas and policy recommendations in their previous book, Brave New Canada, which called for Canada to diversify its economic ties outside the United States, they note how the global and regional environment has shifted dramatically in recent years. A timely and compelling analysis, Braver Canada lays out the challenges for Canada in a rapidly changing, turbulent world and the strategies required for future prosperity.By Frank W. Stahnisch, Erna Kurbegović. 2020
From 1928 to 1972, the Alberta Sexual Sterilization Act, Canada’s lengthiest eugenic policy, shaped social discourses and medical practice in…
the province. Sterilization programs—particularly involuntary sterilization programs—were responding both nationally and internationally to social anxieties produced by the perceived connection between mental degeneration and heredity. Psychiatry and the Legacy of Eugenics illustrates how the emerging field of psychiatry and its concerns about inheritable conditions was heavily influenced by eugenic thought and contributed to the longevity of sterilization practices in Western Canada. Using institutional case studies, biographical accounts, and media developments from Western Canada and Europe, contributors trace the impact of eugenics on nursing practices, politics, and social attitudes, while investigating the ways in which eugenics discourses persisted unexpectedly and remained mostly unexamined in psychiatric practice. This volume further extends historical analysis into considerations of contemporary policy and human rights issues through a discussion of disability studies as well as compensation claims for victims of sterilization. In impressive detail, contributors shed new light on the medical and political influences of eugenics on psychiatry at a key moment in the field’s development.With contributions by Ashley Barlow, W. Mikkel Dack, Aleksandra Loewenau, Diana Mansell, Guel A. Russell, Celeste Tuong Vy Sharpe, Henderikus J. Stam, Douglas Wahlsten, Paul J. Weindling, Robert A. Wilson, Gregor Wolbring, and Marc Workman.By Naranjan S. Dhalla, Grant N. Pierce, Robert E. Beamish. 1988
Published in 1988: The enormous literature, scattered through journals devoted to physiology, biochemistry, pharmacology, ultrastructure, and clinical medicine, together with…
the laboratory observations of the authors, is reviewed and integrated in an effort to portray the origin, evolution, and consequences of heart dysfunction during diabetes.By Milan Halenka, Zden k Fry k. 2017
Combining high-quality ultrasound scans with clear and concise explanatory text this atlas includes side-by-side depictions of various conditions of…
the thyroid both with and without indicative marking Each ultrasound finding is displayed twice six figures per page The left-hand image is a native figure without marks the right-hand image depicts marked findings In this way readers have the opportunity to see the native picture to assess it by themselves and then correct their opinion if necessary Five sections comprise this atlas including the normal thyroid diffuse thyroid lesions both benign and malicious lesions including various carcinomas and rare findings Including nearly 1500 ultrasound scans and covering the range of thyroid conditions Atlas of Thyroid Ultrasonography will be a key reference for endocrinologists radiologists and primary care physicians residents and fellows treating patients with thyroid problemsBy Enrico Agabiti Rosei, Alberto Morganti, Franco Mantero. 2020
This book offers an overview of the latest advances in the epidemiological, pathophysiological, diagnostic and therapeutic aspects of secondary hypertension,…
provided by a group of the most highly respected European experts in this field. It is common belief that secondary forms of hypertension are rare, although in 95% of patients the cause of high blood pressure is unknown – euphemistically referred to as “essential”. There is increasing evidence from epidemiological studies that the prevalence of secondary hypertension is much higher than previously thought, accounting for 20%-25% of all hypertensive patients. There are additional, very good reasons for identifying those patients with secondary hypertension: firstly, they are exposed to a greater risk of suffering major cardiovascular events than patients with essential hypertension who have the same blood pressure level, and for this reason require particular care. Secondly, these patients can be relieved of a lifetime of pharmacological therapy or, at least, have a chance to be treated with more specific and effective medications. A high degree of clinical skill is required to recognize the often vague and subtle symptoms and signs that characterize patients with secondary hypertension, and clinicians need to fully comprehend the mechanisms responsible for the development and maintenance of high blood pressure. Shedding new light on a complex area of cardiovascular medicine, the book enables readers to better treat affected patients.By Andrea Manni, Akuffo Quarde. 2020
This practical guide presents a concise approach to exploring endocrine pathophysiology through the physical exam, emphasizing common clinical signs in endocrinology…
that can be elicited through inspection, palpation, percussion or auscultation. The established and proposed mechanisms underlying these physical signs are highlighted, allowing students, residents and trainees to better appreciate endocrine pathophysiology at the bedside. The text is organized sensibly to facilitate quick and efficient review by medical trainees. Major diseases in endocrinology are grouped by organ systems - pituitary, thyroid, adrenal, and so on. Specific physical examination findings in each primary endocrine disease are reviewed and grouped under the categories of clinical features and pathophysiology, followed by related clinical and pathophysiology pearls. A brief description of the clinical finding is followed by a summary of the pathophysiologic mechanisms underlying the stated clinical finding. Relevant normal physiology and pathophysiology are reviewed where applicable, to facilitate learning. There are numerous texts on the pathophysiologic basis of diagnostic and laboratory findings in endocrinology. There is, however, no dedicated text to address questions that might be asked by trainees. Endocrine Pathophysiology satisfies this need in the literature.