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Sea Trial: Sailing After My Father
By Brian Harvey. 2019
An adventure story set against the backdrop of a son trying to understand his fatherAfter a 25-year break from boating,…
Brian Harvey circumnavigates Vancouver Island with his wife, his dog, and a box of documents that surfaced after his father’s death. John Harvey was a neurosurgeon, violinist, and photographer who answered his door a decade into retirement to find a sheriff with a summons. It was a malpractice suit, and it did not go well. Dr. Harvey never got over it. The box contained every nurse’s record, doctor’s report, trial transcript, and expert testimony related to the case. Only Brian’s father had read it all — until now.In this beautifully written memoir, Brian Harvey shares how after two months of voyaging with his father’s ghost, he finally finds out what happened in the O.R. that crucial night and why Dr. Harvey felt compelled to fight the excruciating accusations.Entry Island
By Peter May. 2016
"A VIVID, FULLY REALIZED NOVEL OF LOST LOVE, YEARNING AND UNBEARABLE HARDSHIP." --Seattle Times"IN A WORD, SUPERLATIVE AND A BOOK…
TO GET LOST IN" --Deadly Pleasures MagazineOnly two kilometers wide and three long, Entry Island is home to a population of just more than 100 inhabitants, the wealthiest of whom has just been discovered murdered in his home. Covered in her husband's blood, the dead man's melancholy wife spins a tale for the police about a masked intruder armed with a knife. The investigation appears to be little more than a formality--the evidence points to a crime of passion by the wife. But homicide detective Sime Mackenzie is electrified by the widow during his interview, convinced that he has met her before, even though this is clearly impossible. Haunted by this strange certainty, Sime's insomnia is punctuated by vivid, hallucinatory dreams of a distant past on a Scottish island 3,000 miles away, dreams in which he and the widow play leading roles. Sime's conviction soon becomes an obsession. And despite mounting evidence of the woman's guilt, he finds himself convinced of her innocence, leading to a conflict between the professional duty he must fulfill and the personal destiny he is increasingly sure awaits him.Since their inception in 1977, the Toronto Blue Jays have been one of the most dynamic franchises in all of…
baseball. As an award-winning, longtime Jays columnist, Bob Elliott has witnessed more than his share of that history up close and personal. In If These Walls Could Talk: Toronto Blue Jays, Elliott provides insight into the Jays' inner sanctum as only he can. Readers will gain the perspective of players, coaches, and front office executives in times of greatness as well as defeat, making for a keepsake no fan will want to miss.Restigouche: The Long Run of the Wild River
By Philip Lee. 2020
Shortlisted, New Brunswick Book Award for Non-FictionA CBC New Brunswick Book List SelectionAn Atlantic Books Today Must-Have New Brunswick Books…
of 2020 SelectionThe Restigouche River flows through the remote border region between the provinces of Quebec and New Brunswick, its magically transparent waters, soaring forest hillsides, and population of Atlantic salmon creating one of the most storied wild spaces on the continent. In Restigouche, writer Philip Lee follows ancient portage routes into the headwaters of the river, travelling by canoe to explore the extraordinary history of the river and the people of the valley. They include the Mi’gmaq, who have lived in the Restigouche valley for thousands of years; the descendants of French Acadian, Irish, and Scottish settlers; and some of the wealthiest people in the world who for more than a century have used the river as an exclusive wilderness retreat.The people of the Restigouche have long been both divided and united by a remarkable river that each day continues to assert itself, despite local and global industrial forces that now threaten its natural systems and the survival of the salmon. In the deep pools and rushing waters of the Restigouche, in this place apart in a rapidly changing natural world, Lee finds a story of hope about how to safeguard wild spaces and why doing so is the most urgent question of our time.The Big 50: The Men And Moments That Made The Toronto Blue Jays (The Big 50)
By Shi Davidi. 2021
The Big 50: Toronto Blue Jays is an extensive and dynamic look at the 50 top moments and figures that…
make the Blue Jays the Blue Jays. In this revised and updated edition, longtime sportswriter Shi Davidi recounts the living history of the Blue Jays, counting down from No. 50 to No. 1. The Big 50: Toronto Blue Jays brilliantly brings to life the Blue Jays remarkable story, from Dave Stieb and Roy Halladay to the roller-coaster that was Roberto Alomar to Joe Carter's 1993 World Series–winning home run and the unforgettable 2016 postseason.Treatment of Thyroid Tumor
By Hitoshi Noguchi, Takahiro Okamoto, Yasuhiro Ito, Hiroshi Takami, Akira Yoshida. 2012
Creating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and…
then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have established positions in clinical practice in North America and in Western European countries. In Japan, however, where radioisotope facilities are of limited availability, treatment plans for differentiated thyroid cancer differ considerably from those of America and Europe, and the associated clinical guidelines need modification before they can be adopted. In addition, although thyroid tumor is a common disease in endocrine practice, its management can differ even among specialists. Thus, a Japanese clinical guideline for the treatment of thyroid tumor was desired by many clinicians. As a combination of evidence-based and consensus-based guidelines for the treatment of thyroid tumor, this book offers alternatives to conventional approaches in the West. Ultimately, the authors hope the guideline will lead to the best possible treatment for patients all over the world in the not-distant future.Everything You Need to Know to Manage Type 2 Diabetes: Simple Steps for Surviving and Thriving with the Low GI Plan
By Kaye Foster-Powell, Jennie Brand-Miller, Stephen Colagiuri, Alan Barclay. 2007
A practical, easy-to-use guide to help you manage type 2 diabetes or prediabetes If you are one of the millions…
of people living with diabetes or prediabetes, you may feel like you're inundated with information on how to manage your condition. The good news is that we now know a lot more about managing diabetes or reducing your risk of developing it--and here, the world's foremost glycemic index experts share their wisdom. Rather than blind you with science or swamp you with facts, Everything You Need to Know to Manage Type 2 Diabetes sets out clearly and simply what you need to eat and do to help you: Reduce your risk of developing diabetes Improve your insulin sensitivity and your cardiovascular health Keep your blood glucose levels, blood pressure, and blood fats under control Reduce your body fat and maintain a healthy body With tips and strategies for working with your doctor, the most recent info on medications, and guidance on the best foods to eat (at home or at a restaurant), Everything You Need to Know to Manage Type 2 Diabetes offers uncomplicated, straightforward advice to help you survive--and thrive.Low GI Diet: Managing Type 2 Diabetes
By Kaye Foster-Powell, Jennie Brand-Miller. 2014
The revised edition of the essential handbook on how to reduce the health risks posed by Type 2 Diabetes -…
from the team behind the internationally bestselling Low GI series. Are you living with type 2 diabetes or pre-diabetes and trying to manage your condition? In Australia and New Zealand alone diabetes and pre-diabetes affect 1 in 4 people. Every day nearly 300 people, including children, develop type 2 diabetes and for every person diagnosed with diabetes there's someone else with undiagnosed diabetes. The good news is that we now know a lot more about managing diabetes or reducing your risk of developing it. Low GI Diet: Managing Type 2 Diabetes cuts through the confusion of conflicting advice and sets out clearly and simply what you need to eat and do to help you: reduce your risk of developing diabetes; improve your cardiovascular health; keep your blood glucose levels, blood pressure and blood fats under control; and maintain a healthy body. This book is a practical guide to help you manage your diabetes or pre-diabetes with diet and lifestyle from the highly qualified, specialist team of authors led by world Low GI authority Professor Jennie Brand-Miller. It shows what you can do for yourself - and why. Best of all, this information is good advice for everyone in your family, not just you.Diabetes and Cardiovascular Disease
By Francesco Paneni, Francesco Cosentino. 2015
This book provides a practical hands-on approach to the management of patients with diabetes and cardiovascular disease, with original and…
up-to-date coverage of a variety of aspects of emerging clinical importance. Practical advice is offered on diagnosis, risk stratification, management of cardiovascular risk factors and available drug therapies. Appropriate myocardial revascularization strategies are explained and the current state of knowledge is documented regarding target-led multifactorial treatment and the management of acute coronary syndromes, heart failure, and cerebrovascular disease. New algorithms for diagnosis and treatment are presented and to ensure ease of reference each chapter includes a box with practical recommendations as well as informative color illustrations and tables. The handbook will be of value for all cardiologists and diabetologists and will be especially helpful for young cardiologists, who are ever more frequently confronted by patients with diabetes and cardiovascular disease.Genetic Damage in Human Spermatozoa
By Monica Muratori, Elisabetta Baldi. 2014
There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate…
during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.Thymic Development and Selection of T Lymphocytes
By Thomas Boehm, Yousuke Takahama. 2014
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place.…
Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.Moon Ontario
By Carolyn Heller. 2015
Professional travel writer Carolyn B. Heller shares the best ways to experience all that Ontario has to offer, from scuba…
diving shipwrecks in the Great Lakes to dining on contemporary fare at Toronto's hottest restaurants. Heller leads readers to the highlights of this fascinating region with trip ideas such as Food and Wine Touring, Active Adventures, and History and Culture-providing different approaches for different kinds of travelers. Complete with tips on enjoying more than just the falls on the Niagara peninsula, hopping a ferry to Pelee Island for wine-tasting and relaxation, and ice skating on the world's longest skating rink in Ottawa, Moon Ontario gives travelers the tools they need to create a more personal and memorable experience.Obesity and Breast Cancer
By Kristy A. Brown, Evan R. Simpson. 2014
Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been…
shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are oestrogen-dependent. Since the ovaries no longer produce oestrogens after menopause, and that circulating levels are negligible, it is evident that it is the oestrogens produced locally within the breast adipose that are responsible for the increased growth of breast cancer cells. Aromatase is the enzyme that converts androgens into oestrogens and its regulation is dependent on the activity of a number of tissue-specific promoters. Targeting oestrogen biosynthesis in obesity may be useful for the prevention of breast cancer. Aromatase inhibitors are efficacious at treating postmenopausal breast cancer and recent studies suggest that they may also be useful in the prevention setting. However, these compounds inhibit the catalytic activity of aromatase and as a consequence lead to a number of undesirable side-effects, including arthralgia and possible cognitive defects due to inhibition of aromatase in the bone and brain, respectively. Novel therapies, such as those employed to treat obesity-associated disease, including anti-diabetics, may prove successful at inhibiting aromatase specifically within the breast. This SpringerBrief will explore all of these issues in depth and the authors are in a unique position to write about this topic, having extensive experience in the field of aromatase research.Moon Banff National Park: Including Banff And Jasper National Parks (Moon Handbooks Ser.)
By Andrew Hempstead. 2016
Join Canadian resident and avid outdoorsman Andrew Hempstead on an unforgettable adventure. With his unique perspective and advice you can…
trust, Moon Banff National Park has everything you need to know to explore the great outdoors.Moon Banff National Park shows travelers the best way to experience all Banff has to offer-from savoring the spectacular backdrop of glacial lakes and lush forests, to spotting wildlife like black bears, elk, and bighorn sheep. Hemstead includes unique trip ideas, such as taking a sleigh ride through the snow, or riding though the sky in a mountain gondola. Complete with details on escaping the crowds at Lake Louise, camping out under the stars, and dining in Banff, Moon Banff National Park provides travelers with all the necessary tools to head outdoors.With expertly crafted maps and gorgeous photos, this full-color guidebook gives you the tools you need to have an immersive and unique experience.Moon Banff National Park includes areas such as:Town of BanffLake Louise and VicinityIcefields ParkwayNearby ParksFind the Moon guide that best suits your trip! Exploring more of Canada's National Parks? Try Moon Canadian Rockies.The Cleveland Clinic Manual of Dynamic Endocrine Testing
By Ahmet Bahadir Ergin, A. Laurence Kennedy, Manjula K. Gupta, Amir H. Hamrahian. 2015
Developed via a peer review process that included 25 experienced endocrinologists and utilizing the best current evidence, The Cleveland Clinic…
has created a practical set of protocols for over 25 commonly used dynamic endocrine tests. The cornerstone of clinical endocrinology, these evidence-based protocols play an important role in clinical decision-making and are important element of billing and compliance with high quality standards. Included here are various tests for pituitary and adrenal disorders, thyroid disorders, and glucose metabolism and pancreatic disorders, presented systematically with indications, preparation, materials needed, precautions, procedure, interpretation, and caveats. Filling the gap left by a lack of national guidelines, The Cleveland Clinic Manual of Dynamic Endocrine Testing is an up-to-date practical guide for endocrinologists, nurses, and their staff, inside or outside of the US, who need to perform and interpret dynamic endocrine testing in their everyday practice, as well as medical students, residents and fellows who have interest in endocrinology.Stem Cell Therapy in Lysosomal Storage Diseases
By Jaap Jan Boelens, Robert Wynn. 2013
Stem Cell therapy for lysosomal diseases (LSDs) is developing rapidly. This volume discusses the history, current practice and future perspectives…
of stem cells in inborn errors of metabolism (IEM) and provides an international perspective on progress, limitations, and future directions (e. g. gene therapy, iPS, ES) in the field. Beginning with an overview of these diseases, the book covers the breadth of this topic from treatment options, bone marrow transplantation, and alternative treatment options, through long-term outcomes and future perspectives.Therapeutic Perspectives in Type-1 Diabetes
By Prachi Singh, Ganesh R Kokil, Karnaker R Tupally, Kingshuk Poddar, Aaron Tan, Venky Venkatesan, Harendra S. Parekh, Giorgia Pastorin. 2016
This book provides critical insights into and appraisals ofrecent breakthroughs in type 1 diabetes modulation, with a particular emphasison the…
potential impact of current prevention and treatment strategies. It alsodiscusses recent successes and failures in clinical trials. Presenting ancomprehensive overview of the disease, it is especially useful for newcomers inthe field. It also includes illustrations, which make it easy for the reader tograsp the basic concepts involved. Furthermore, the tables include concise andeasy-to-understand information on current clinical trials.Diabetes Management in Clinical Practice
By Tahseen A. Chowdhury. 2014
At a time when clinicians are bombarded with masses of clinical information from numerous sources, and the wide variety of…
changes/advances in diabetes management, there is a need for a concise, easy-to-read book that provides an up-to-date review of the major advances in management of diabetes, with an evidence-based approach. This book is a collection of short chapters, each focused on a subject related to the management of diabetes and its complications. The chapters are written by acknowledged experts in the field, who are also clinicians dealing with diabetes on a day-to-day basis. The text is highly evidence based and well referenced with reviews of relevant trials. It includes the latest developments in diabetes management, prospects for future therapies and avenues of research, as well as therapies currently undergoing clinical trial. In order to facilitate ease of reading, it has a user-friendly appearance, with multiple headings, illustrations and summary boxes. The primary audience is clinical, including all healthcare professionals involved in the management of diabetes and its complications. This encompasses diabetologists and endocrinologists, family practitioners with an interest in diabetes, specialist nurses, dietitians and podiatrists.Moon Montréal & Québec City
By Sacha Jackson. 2014
Writer Sacha Jackson guides travelers to the highlights of Montréal and Québec City, from the trendy bars, restaurants, and festivals…
of Montréal to the original city walls and historic center of Québec City. Jackson also offers unique trip ideas like Romantic Weekend Getaways and Montréal on the Cheap. Complete with details on kayaking the Lachine canal, eating your own weight in poutine, and participating in the concerts, parades, and sleigh races of the Carnaval de Québec, Moon Montréal & Québec City gives travelers the tools they need to create a more personal and memorable experience.Glycemic Control in the Hospitalized Patient
By Lillian F. Lien, Leonor Corsino, Mark N. Feinglos, Mary E. Cox. 2011
Glycemic Control in the Hospitalized Patient: A Comprehensive Clinical Guide is a unique, practical resource for health care providers dealing…
with hyperglycemia in the inpatient setting. Outlining a hands-on approach used by the Duke University Inpatient Diabetes Management team, the book discusses a wide range of scenarios that occur while treating patients with hyperglycemia, including challenging circumstances such as steroids and tube feeding regimens. Special emphasis is given to insulin therapy. The chapters are written by a group of health care providers with extensive, pioneering experience in hyperglycemia control in the inpatient setting at the Duke University Medical Center. The book includes the most up-to-date scientific evidence and information and is addressed to not only hospitalists and general internists but also endocrinology fellows, residents, nurse practitioners, nurses, and other primary care practitioners who treat patients in the inpatient setting. The focus is clearly on practical, patient-care topics. Glycemic Control in the Hospitalized Patient: A Comprehensive Clinical Guide is a first-of-its kind, comprehensive guide to state-of-the-art inpatient glycemic management.