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Handbook of PAF and PAF Antagonists (Routledge Revivals)
By LPierre Braquet. 1991
Published in 1991: Since its characterization in the 1970s from antigen-stimulated rabbit basophils, platelet-activating factor (PAF) has been demonstrated to…
be produced by, and act upon, a variety of cell types. PAF antagonists, which have been obtained from both natural sources and chemical synthesis, now represent a new class of therapeutic agents and may provide new prospects for treating several major pathologies, particularly shock, ischemia and asthma. This book provides a unique overview of the chemistry, molecular modeling, pharmacology, and clinical potential of the major classes of natural and synthetic PAF antagonists. Compounds reviewed include the ginkgolides, diketopiperazines, neolignans, hetrazepines, cyclic and 1,3-dioxolan derived PAF analogs, pyrrolo[1,2-c]thiazoles, imidazo[2,1-a]isoquinolines and pyridoquinazoline carboxamides. Consisting of 12 chapters written by leading experts in PAF antagonist research, this book is essential reading for students, researchers, clinicians, and medical practitioners involved in this rapidly developing field of biomedical research.How to Find Information About AIDS: Second Edition
By M Sandra Wood, Jeffrey T Huber, Virginia A Lingle. 1992
If you have ever attempted to research the AIDS epidemic or the HIV virus, you have discovered the overwhelming array…
of information sources. How do you know which information is the most accurate and most current? This second edition contains a directory of sources and resources in the AIDS information arena, designed to make it easy for anyone to find information on AIDS.Important Topics Covered: Organizations--includes AIDS service organizations, community-based organizations, and organizations operating at the local, regional, state, and national level Health Departments--identifies state offices, including the District of Columbia, that provide AIDS-related information or that can refer individuals to the appropriate organization Research Institutions, Grant Funding Sources, Education and Training Centers, and Federal Agencies Hotlines--both local and national Electronic Sources of Information--includes specific journals, bibliographies, and monographs Audiovisual Producers--covers producers of audiovisuals concerning AIDSThe organization of the directory and the indexes, arranged geographically as well as alphabetically, are compelling features of this timely book. How to Find Information About AIDS, Second Edition is a valuable addition to the reference collection of librarians, counselors, school teachers, AIDS organization administrators, and medical personnel.Chemistry and Biochemistry of Flavoenzymes: Volume II
By Franz Muller. 1991
Chemistry and Biochemistry of Flavoenzymes summarizes the present knowledge of the chemical and physical properties of free flavin, modified flavins…
occurring in nature, and deazaflavin. This information forms the fundamental basis for understanding the catalytic properties of flavoenzymes. Flavoproteins involved in transport, electron transfer, oxidation, dehydrogenation and hydroxylation reactions are discussed with respect to their biochemical and biophysical properties. The book presents the catalytic mechanisms of the flavoproteins in detail and, where available, three-dimensional structures and molecular biology data are included. The medical aspects of free and protein-bound flavin are also briefly discussed. Chemistry and Biochemistry of Flavoenzymes is an essential reference source for chemists, biochemists, toxicologists, biologists, pharmacologists, and researchers in the pharmaceutical industry.Non-Traditional Feeds for Use in Swine Production (CRC Press Revivals)
By Phillip A Thacker, Roy N Kirkwood. 1992
Feed represents the single greatest expense associated with bringing pigs to market weight. Therefore, if you can reduce the cost…
of feeding without detriment to pig performance, the economics of swine production will improve. The ingredient list for swine rations has become fairly limited, and the majority of diets fed to pigs consist of a few staples, such as corn, wheat, barley, and soybean meal. Non-Traditional Feeds for Use in Swine Production explores over fifty non-traditional feedstuffs in terms of their nutritional content and their viability as alternative, cost effective food sourcesMental Disorder Among Prisoners: Toward an Epidemiologic Inventory
By Nathaniel Pallone. 1991
What do we know about the mental health of inmates? What are the implications of what we know? Nathaniel J.…
Pallone characterizes opinion on these questions as falling into two broad camps: the "tender-hearted," those who see an overlap between mental illness and criminal behavior, and are treatment-oriented; and the "tough-minded," those who have little confidence in psychiatric categories, do not really accept arguments about diminished responsibility, and who feel the emphasis should be on punishment. Which is closer to the truth?When this book was first published, the incidence of mental disorder among prisoners was nearly four times greater than among comparable groups in the general population in part because prisoners are disproportionately drawn from demographic groups with a high incidence of mental disorder—nonwhite and from lower socioeconomic strata. But other data is equally dismaying: mental retardation is 50 percent higher; alcohol and drug abuse is between five and eight times greater; and neurogenic disorders may be 1,700 times greater. In all categories of mental illness, the incidence among prisoners is far higher than among the general population.Pallone asserts that evidence suggests that the design and implementation of mental health care needs serious reevaluation, particularly in view of Supreme Court decisions mandating mental health care despite obstacles with implementation. Palone saw mental health care as the primary issue for those who manage prisons. Sadly, this remains as true as when this book was first published.Venous Ultrasound
By Joseph A. Zygmunt. 2020
Venous Ultrasound 2e is the essential text for anyone involved in the treatment of chronic venous disease. It provides specific…
information on ultrasound as it is applied to chronic insufficiency, including history, general techniques, examples of anatomy, and protocols for performing ultrasound on patients, and discussions on key aspects of interpretation of sonographic findings. Updated to include the outcome and impact of three recent studies, the ATTRACT trial, the EVRA study, and the VIDIO imaging trial. An entire chapter is dedicated to iliac venous and stent imaging for those interested in expanding practice based on the mentioned studies. Also included is specific protocol for imaging of the pelvic area with focus on the pelvic congestion and reflux affecting this anatomic area. This text demonstrates that as imaging techniques improve, so too will the understanding of venous pathologies increase and the burdens of their respective pathologies. Pelvic Congestion, iliofemoral and late stage disease can be interrogated with a non-invasive approach using the techniques included prior to interventional procedures. This fully updated new edition includes coverage of new ablation techniques which include non- thermal and non- tumescent therapies for venous insufficiency – these have unique ultrasound properties on what to see, look for and observe in intra and post- operative situations. Focusing on the fundamentals that every phlebologist needs to know, the color illustrations and numerous line drawings complement the text for a complete learning experience. Key features: Covers anatomy related to venous insufficiency and obstruction Protocols with step by step approaches for those new to certain exams Includes useful diagrams and images to aid understanding Thoroughly up to date, with all the latest information for those practicing venous therapies Venous Ultrasound 2e is valuable for sonographers and physicians alike; including phlebologists, general and vascular surgeons, physicians, radiologists, angiologists, interventional cardiologist, mid-levels, and nurses who work in this area.Asphyxiation, Suffocation, and Neck Pressure Deaths
By Burkhard Madea. 2020
Combining theory and practice, this is a comprehensive analysis of suffocation, asphyxiation, and neck pressure deaths. It includes important developments…
in the field such as lung histomorphology in fatal strangulation, systematic dissection of the larynx, biochemical findings, and post-mortem imaging. Given the significant challenges in accuratelTopology and Physics of Circular DNA (CRC Press Revivals)
By Alexander Vologodskii. 1992
Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how…
topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.Medical Journals and Medical Knowledge: Historical Essays (Routledge Library Editions: History of Medicine #1)
By Roy Porter, William F. Bynum, Stephen Lock. 1992
Originally published in 1992 Medical Journals and Medical Knowledge examines both broad developments in print and media and the practice…
of particular journals such as the British Medical Journal. The book is the first study to address these questions and to examine the impact of regular news on the making of the medical community. The book considers the rise of the medical press, and looks at how it recorded and described principal developments and so promoted medical science and enhanced medical consciousness. This book was a seminal work when first published and was one of the first to consider the importance of the roots of medical journalism, editorial practices and the ways in which the medical journalism altered the world of medicine.Leihmutterschaft und Familie: Impulse aus Recht, Theologie und Medizin
By Edward Schramm, Michael Wermke. 2018
Das Buch betrachtet das Thema Leihmutterschaft aus einer breit angelegten interdisziplin ren Perspektive In Deutschland ist die…
Leihmutterschaft verboten in vielen anderen L ndern legal Viele Menschen erf llen sich den Wunsch nach einem Kind daher im Wege einer Leihmutterschaft im Ausland Das Buch nimmt dies zum Anlass aktuelle Erkenntnisse und Impulse aus der Rechtswissenschaft Theologie Soziologie kindlichen Entwicklungspsychologie Medizin Genetik und Philosophie zu diesem Ph nomen aufzugreifen und zu analysieren Im Mittelpunkt steht die Frage inwiefern sich das Wohl des Kindes die Interessen der Leihm tter sowie die Bed rfnisse der Wunscheltern in der deutschen Rechtsordnung der sozialen Wirklichkeit und den kirchlichen Institutionen widerspiegelnToxic Safety: Flame Retardants, Chemical Controversies, and Environmental Health
By Alissa Cordner. 2016
Initially marketed as a life-saving advancement, flame retardants are now mired in controversy. Some argue that data show the chemicals…
are unsafe while others continue to support their use. The tactics of each side have far-reaching consequences for how we interpret new scientific discoveries.An experienced environmental sociologist, Alissa Cordner conducts more than a hundred interviews with activists, scientists, regulators, and industry professionals to isolate the social, scientific, economic, and political forces influencing environmental health policy today. Introducing "strategic science translation," she describes how stakeholders use scientific evidence to support nonscientific goals and construct "conceptual risk formulas" to shape risk assessment and the interpretation of empirical evidence. A revelatory text for public-health advocates, Toxic Safety demonstrates that while all parties interested in health issues use science to support their claims, they do not compete on a level playing field and even good intentions can have deleterious effects.Autism's False Prophets: Bad Science, Risky Medicine, and the Search for a Cure
By Paul Offit. 2008
A London researcher was the first to assert that the combination measles-mumps-rubella vaccine known as MMR caused autism in children.…
Following this "discovery," a handful of parents declared that a mercury-containing preservative in several vaccines was responsible for the disease. If mercury caused autism, they reasoned, eliminating it from a child's system should treat the disorder. Consequently, a number of untested alternative therapies arose, and, most tragically, in one such treatment, a doctor injected a five-year-old autistic boy with a chemical in an effort to cleanse him of mercury, which stopped his heart instead. Children with autism have been placed on stringent diets, subjected to high-temperature saunas, bathed in magnetic clay, asked to swallow digestive enzymes and activated charcoal, and injected with various combinations of vitamins, minerals, and acids. Instead of helping, these therapies can hurt those who are most vulnerable, and particularly in the case of autism, they undermine childhood vaccination programs that have saved millions of lives. An overwhelming body of scientific evidence clearly shows that childhood vaccines are safe and does not cause autism. Yet widespread fear of vaccines on the part of parents persists. In this book, Paul A. Offit, a national expert on vaccines, challenges the modern-day false prophets who have so egregiously misled the public and exposes the opportunism of the lawyers, journalists, celebrities, and politicians who support them. Offit recounts the history of autism research and the exploitation of this tragic condition by advocates and zealots. He considers the manipulation of science in the popular media and the courtroom, and he explores why society is susceptible to the bad science and risky therapies put forward by many antivaccination activists.Traditional Chinese Medicine: Heritage and Adaptation
By Paul U. Unschuld. 2018
A leading authority explains the ideas and practice of Chinese medicine from its beginnings in antiquity to today. Paul U.…
Unschuld describes medicine's close connection with culture and politics throughout Chinese history. He brings together texts, techniques, and worldviews to understand changing Chinese attitudes toward healing and the significance of traditional Chinese medicine in both China and the Western world.Unschuld reveals the emergence of a Chinese medical tradition built around a new understanding of the human being, considering beliefs in the influence of cosmology, numerology, and the supernatural on the health of the living. He describes the variety of therapeutic approaches in Chinese culture, the history of pharmacology and techniques such as acupuncture, and the global exchange of medical knowledge. Insights are offered into the twentieth-century decline of traditional medicine, as military defeats caused reformers and revolutionaries to import medical knowledge as part of the construction of a new China. Unschuld also recounts the reception of traditional Chinese medicine in the West since the 1970s, where it is often considered an alternative to Western medicine at the same time as China seeks to incorporate elements of its medical traditions into a scientific framework. This concise and compelling introduction to medical thought and history suggests that Chinese medicine is also a guide to Chinese civilization.This innovative book clarifies the distinction between philosophy of medicine and medical philosophy, expanding the focus from the 'knowing that'…
of the first to the 'knowing how' of the latter. The idea of patient and provider self-discovery becomes the method and strategy at the basis of therapeutic treatment. It develops the concept of 'Central Medicine', aimed at overcoming the dichotomies of Western–Eastern medicine and Traditional–Integrative approaches. Evidence-based and patient-centered medicine are analyzed in the context of the debate on placebo and non-specific effects alongside clinical research on the patient-doctor relationship, and the interactive nature of human relationships in general, including factors such as environment, personal beliefs, and perspectives on life's meaning and purpose. Tomasi's research incorporates neuroscience, psychology, philosophy, and medicine in a clear, readable, and detailed way, satisfying the needs of professionals, students, and anyone who enjoys the exploration of the complexity of human mind, brain, and heart.Akutes Abdomen im Kindes- und Jugendalter: Grundlagen - Diagnose - Erstversorgung - Therapie
By Johannes Mayr, Günter Fasching. 2018
Dieses Werk bildet den aktuellen Stand aller wichtigen Aspekte von Diagnose Management und Therapie unklarer Bauchschmerzen im Kindes- und…
Jugendalter ab die zu den h ufigsten Notfallsituationen in der rztlichen Praxis wie auch im Krankenhaus geh ren In einem allgemeinen Teil werden die physiologischen Besonderheiten Kinderanalgesie Pharmakotherapie und An sthesie bei jungen Patienten sowie radiologische Aspekte und Kommunikationshilfen vorgestellt Der speziell Teil widmet sich ausf hrlich den einzelnen h ufigen Krankheitsbildern f r die Altersgruppen der Neugeborenen Kleinkinder sowie f r Kinder im Schulalter und Adoleszente Anschauliche Farbabbildungen und die didaktische Struktur der Kapitel erleichtern die Informationsaufnahme Fallbeispiele und Praxistipps helfen das Wissen im Arbeitsalltag umzusetzen Das Buch richtet sich in erster Linie an Kinderchirurgen Allgemeinchirurgen P diater Not rzte und andere mit dem Krankheitsbild konfrontierte rztenGenes, Brains, and Human Potential: The Science and Ideology of Intelligence
By Ken Richardson. 2017
For countless generations people have been told that their potential as humans is limited and fundamentally unequal. The social order,…
they have been assured, is arranged by powers beyond their control. More recently the appeal has been to biology, specifically the genes, brain sciences, the concept of intelligence, and powerful new technologies. Reinforced through the authority of science and a growing belief in bio-determinism, the ordering of the many for the benefit of a few has become more entrenched. Yet scientists are now waking up to the influence of ideology on research and its interpretation. In Genes, Brains, and Human Potential, Ken Richardson illustrates how the ideology of human intelligence has infiltrated genetics, brain sciences, and psychology, flourishing in the vagueness of basic concepts, a shallow nature-versus-nurture debate, and the overhyped claims of reductionists. He shows how ideology, more than pure science, has come to dominate our institutions, especially education, encouraging fatalism about the development of human intelligence among individuals and societies. Genes, Brains, and Human Potential goes much further: building on work being done in molecular biology, epigenetics, dynamical systems, evolution theory, and complexity theory, it maps a fresh understanding of intelligence and the development of human potential. Concluding with an upbeat message for human possibilities, this synthesis of diverse perspectives will engender new conversations among students, researchers, and other interested readers.Science has long treated religion as a set of personal beliefs that have little to do with a rational understanding…
of the mind and the universe. However, B. Alan Wallace, a respected Buddhist scholar, proposes that the contemplative methodologies of Buddhism and of Western science are capable of being integrated into a single discipline: contemplative science.The science of consciousness introduces first-person methods of investigating the mind through Buddhist contemplative techniques, such as samatha, an organized, detailed system of training the attention. Just as scientists make observations and conduct experiments with the aid of technology, contemplatives have long tested their own theories with the help of highly developed meditative skills of observation and experimentation. Contemplative science allows for a deeper knowledge of mental phenomena, including a wide range of states of consciousness, and its emphasis on strict mental discipline counteracts the effects of conative (intention and desire), attentional, cognitive, and affective imbalances.Just as behaviorism, psychology, and neuroscience have all shed light on the cognitive processes that enable us to survive and flourish, contemplative science offers a groundbreaking perspective for expanding our capacity to realize genuine well-being. It also forges a link between the material world and the realm of the subconscious that transcends the traditional science-based understanding of the self.The Alchemy of Disease: How Chemicals and Toxins Cause Cancer and Other Illnesses
By John Whysner. 2019
Since the dawn of the industrial age, we have unleashed a bewildering number of potentially harmful chemicals. But out of…
this vast array, how do we identify the actual threats? What does it take to prove that a certain chemical causes cancer? How do we translate academic knowledge of the toxic effects of particular substances into understanding real-world health consequences? The science that answers these questions is toxicology.In The Alchemy of Disease, John Whysner offers an accessible and compelling history of toxicology and its key findings. He details the experiments and discoveries that revealed the causal connections between chemical exposures and diseases. Balancing clear accounts of groundbreaking science with human drama and public-policy relevance, Whysner describes key moments in the development of toxicology and their thorny social and political implications. The book features discussions of toxicological problems past and present, including DDT, cigarettes and other carcinogens, lead poisoning, fossil fuels, chemical warfare, pharmaceuticals—including opioids—and the efficacy of animal testing. Offering valuable insight into the science and politics of crucial public-health concerns, The Alchemy of Disease shows that toxicology’s task—pinpointing the chemical cause of an illness—is as compelling as any detective story.The Stigma Effect: Unintended Consequences of Mental Health Campaigns
By Patrick Corrigan. 2019
Despite efforts to redress the prejudice and discrimination faced by people with mental illness, a pervasive stigma remains. Many well-meant…
programs have attempted to counter stigma with affirming attitudes of recovery and self-determination. Yet the results of these efforts have been mixed. In The Stigma Effect, psychologist Patrick W. Corrigan examines the unintended consequences of mental health campaigns and proposes new policies in their place.Corrigan analyzes the agendas of government agencies, mental health care providers, and social service agencies that work with people with mental illness, dissecting how their best intentions can misfire. For example, a campaign to change the language around mental illness by replacing supposedly stigmatizing words with empowering ones has made little difference in how people with mental health conditions are viewed. Educational programs that frame mental illness as a brain disorder have made the general public less likely to blame people for their illnesses, but also skeptical that such conditions can be cured. Ultimately, Corrigan argues that effective strategies require leadership by those with lived experience, as their recovery stories replace ideas of incompetence and dangerousness with ones of hope and empowerment. As an experienced clinical researcher, as an advocate, and as a person who has struggled with such prejudices, Corrigan challenges readers to carefully examine anti-stigma programs and reckon with their true effects.In this fascinating book, Johanna Emeney examines the global proliferation of new poetry related to illness and medical treatment from…
the perspective of doctors, patients, and carers in light of the growing popularity of the medical humanities. She provides a close analysis of poetry from New Zealand, the U.S., and the U.K. that deals with sociological and philosophical aspects of sickness, ailment, medical treatment, care, and recuperation.