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Wikipenis: Dr. Nicola's Penis Book—Maintenance, Prevention, and Care
By Dr Nicola Mondaini, Patrizia Prezioso. 2021
A taboo-breaking guide to the male sexual and urinary system, raising awareness of anatomy, upkeep, and the emergencies that can…
occur throughout a lifetime. When it comes to men and their medical health, age can lead to a distressing lack of discussion. Boyhood curiosity gives way to reticence in adult men, a discomfort in asking questions and sharing insecurities about their own bodies—especially when it comes to the penis. Though highly focused on in art, daily conversations, and even spam emails, the general public&’s knowledge of the form, function, and evolution of the penis is sorely lacking. This knowledge gap is the inspiration for Wikipenis. With this book, urologist Nicola Mondaini offers men and the women in their lives—mothers, grandmothers, girlfriends, and wives—a learning tool for the healthy and correct care of the male genital system. Four chapters cover childhood, adolescence, adulthood, and old age. Readers can flip to relevant sections to learn about maintenance, diseases, and hazards related to each stage of development. A comprehensive and authoritative handbook, Wikipenis includes information on: Penis structure and function Circumcision and hygiene Effects of smoking, drugs, alcohol consumption, and obesity Sexually transmitted diseases Erectile dysfunction Prostate pathologies Penile cancer Gender dysphoria Piercings Testosterone And more Wikipenis aims to establish a preventative culture from the start, to redesign the relationship between boys and this part of their body—a user&’s guide that men can consult whenever necessary for a happy and healthy life. &“A valuable addition to the world&’s literature on this important topic.&” —John P. Mulhall, Director of Male Sexual and Reproductive Medicine, Memorial Sloan Kettering Cancer CenterWhy We Need Vaccines: How Humans Beat Infectious Diseases (Orca Timeline #6)
By Rowena Rae. 2024
Vaccination is one of humanity's most effective and greatest discoveries. Infections like the plague, smallpox and other deadly diseases have…
affected and killed people for thousands of years, but the invention of vaccines forever changed our relationship with these diseases. More recently the urgency of developing an effective vaccine during the COVID-19 pandemic brought vaccination to the public's attention. Simmering tensions around vaccine hesitancy, misinformation and mistrust of science came to the forefront. Although an earlier form of protection against infectious diseases has been practiced for a long time, vaccines have only been around for 200 years. Why We Need Vaccines explores the history of vaccine discovery, the science of how vaccines work and the public-health achievements that vaccines have made possible. It also discusses vaccine mandates and inequality in access to vaccines on local and global scales. It challenges young readers to take responsibility for themselves, their families and their communities so we can all be part of the solution to take down infectious diseases.Ancestral Genomics: African American Health in the Age of Precision Medicine
By Constance B. Hilliard. 2024
A leading evolutionary historian offers a radical solution to racial health disparities in the United States.Constance B. Hilliard was living…
in Japan when she began experiencing joint pain. Her doctor diagnosed osteoarthritis—a common ailment for someone her age. But her bloodwork showed something else: Hilliard, who had never had kidney problems, appeared to be suffering from renal failure. When she returned to Texas, however, a new round of tests showed that her kidneys were healthy. Unlike the Japanese doctor, her American primary care provider had checked a box on her lab report for “African American.” As a scholar of scientific racism, Hilliard was perplexed. Why should race, which experts agree has no biological basis, matter for getting accurate test results?Ancestral Genomics is the result of Hilliard’s decade-long quest to solve this puzzle. In a masterful synthesis of evolutionary history, population genetics, and public health research, she addresses the usefulness of race as a heuristic in genomic medicine. Built from European genetic data, the Human Genome Project and other databases have proven inadequate for identifying disease-causing gene variants in patients of African descent. Such databases, Hilliard argues, overlook crucial information about the environments to which their ancestors’ bodies adapted prior to the transatlantic slave trade. Hilliard shows how, by analyzing “ecological niche populations,” a classification model that combines family and ecological histories with genetic information, our increasingly advanced genomic technologies, including personalized medicine, can serve African Americans and other people of color, while avoiding racial essentialism.Forcefully argued and morally urgent, Ancestral Genomics is a clarion call for the US medical community to embrace our multigenomic society.Navigating Communication with Seriously Ill Patients: Balancing Honesty with Empathy and Hope
By null Robert M. Arnold, null Anthony L. Back, null Elise C. Carey, null James A. Tulsky, null Gordon J. Wood, null Holly B. Yang. 2009
When clinicians communicate effectively, patients retain more information, have higher trust and a better quality of life. Such a patient-centred…
approach is the future of clinical care, and this book is an essential how-to guide on improving these skills. Grounded in innovative and evidence-based methodology, perfected through over twenty years of teaching in the VitalTalk training program, content includes foundational communication skills, how to help patients plan for the future, what to do when you are really stuck, and strategies to work through conflicts with colleagues. In this updated edition, emphasis is placed on the roles privilege, race, and power play in the medical encounter, and new tools are provided to help clinicians navigate this landscape with greater self-awareness and sensitivity. This practical guide is filled with skills and roadmaps, demonstrating how to be clearer when sharing information, more competent at understanding patient concerns, and more effective when making recommendations.Dose-Response Analysis Using R (Chapman & Hall/CRC The R Series)
By Christian Ritz, Signe Marie Jensen, Daniel Gerhard, Jens Carl Streibig. 2020
Nowadays the term dose-response is used in many different contexts and many different scientific disciplines including agriculture, biochemistry, chemistry, environmental…
sciences, genetics, pharmacology, plant sciences, toxicology, and zoology.In the 1940 and 1950s, dose-response analysis was intimately linked to evaluation of toxicity in terms of binary responses, such as immobility and mortality, with a limited number of doses of a toxic compound being compared to a control group (dose 0). Later, dose-response analysis has been extended to other types of data and to more complex experimental designs. Moreover, estimation of model parameters has undergone a dramatic change, from struggling with cumbersome manual operations and transformations with pen and paper to rapid calculations on any laptop. Advances in statistical software have fueled this development.Key Features: Provides a practical and comprehensive overview of dose-response analysis. Includes numerous real data examples to illustrate the methodology. R code is integrated into the text to give guidance on applying the methods. Written with minimal mathematics to be suitable for practitioners. Includes code and datasets on the book’s GitHub: https://github.com/DoseResponse. This book focuses on estimation and interpretation of entirely parametric nonlinear dose-response models using the powerful statistical environment R. Specifically, this book introduces dose-response analysis of continuous, binomial, count, multinomial, and event-time dose-response data. The statistical models used are partly special cases, partly extensions of nonlinear regression models, generalized linear and nonlinear regression models, and nonlinear mixed-effects models (for hierarchical dose-response data). Both simple and complex dose-response experiments will be analyzed.The Black Angels: The Untold Story of the Nurses Who Helped Cure Tuberculosis
By Maria Smilios. 2023
New York City, 1929. A sanatorium, a deadly disease, and a dire nursing shortage. In the pre-antibiotic days when tuberculosis…
stirred people&’s darkest fears, killing one in seven, white nurses at Sea View, New York&’s largest municipal hospital, began quitting en masse. Desperate to avert a public health crisis, city officials summoned Black southern nurses, luring them with promises of good pay, a career, and an escape from the strictures of Jim Crow. But after arriving, they found themselves on an isolated hilltop in the remote borough of Staten Island, yet again confronting racism and consigned to a woefully understaffed sanatorium, dubbed &“the pest house,&” where it was said that &“no one left alive.&” Spanning the Great Depression and moving through World War II and beyond, this remarkable true story follows the intrepid young women known by their patients as the &“Black Angels.&” For twenty years, they risked their lives working under appalling conditions while caring for New York&’s poorest residents, who languished in wards, waiting to die, or became guinea pigs for experimental surgeries and often deadly drugs. But despite their major role in desegregating the New York City hospital system—and their vital work in helping to find the cure for tuberculosis at Sea View—these nurses were completely erased from history. The Black Angels recovers the voices of these extraordinary women and puts them at the center of this riveting story, celebrating their legacy and spirit of survival.Public Health Entomology
By Jerome Goddard. 2022
In the struggle against vector-borne diseases, it is critical that we bridge the gap among vector control workers on the…
ground (practitioners), public health planners and administrators, and (academic) medical entomologists. This second edition of Public Health Entomology is designed to fit certificate courses in public health entomology offered by universities and U.S. Centers of Excellence. It comprehensively examines vector-borne disease prevention, surveillance, and control from a governmental and public health perspective with worldwide application.Divided into two sections, the book begins with a historical account of the early beginnings of pest control and public health. Next, it outlines the concepts, design, and implementation of a sound public health entomology program, including issues associated with pesticide use, FEMA and other disaster response entities, and an adverse, chemophobic public. The second section provides an overview of some of the most common public health pests that are found globally. Copious photos and line drawings accentuate the text, along with text boxes and sidebars. The new edition addresses "IPM and Alternative Control Methods" in each section, expands the Lyme disease section, and includes other new and emerging tick-borne diseases (TBD). It provides enhanced discussion of working with local political figures and jurisdictions, as well as partnerships with academia, and is generally more worldwide in scope. Author Jerome Goddard designed and implemented the vector control program along the Mississippi Gulf Coast after Hurricane Katrina. His ability to communicate his knowledge and experience to public health students, professionals, and the general public make this book an essential resource for preventing disease from these vector-borne threats.Antioxidants and Functional Foods for Neurodegenerative Disorders: Uses in Prevention and Therapy
By Abhai Kumar, Debasis Bagchi. 2021
Neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are a growing problem across the world’s aging population. Oxidative stress in the…
brain plays a central role in a common pathophysiology of these diseases. This book presents scientific research on the potential of antioxidant therapy in the prevention and treatment of neurodegenerative disorders.This book outlines the roles of oxidative stress and diabetes mellitus in neurodegeneration, describes the molecular mechanisms of neurodegenerative disorders including the roles of environmental pollutants and inflammatory responses, and explores mitochondrial dysfunction. It then describes the protective abilities of antioxidants – including vitamin D, tocotrienol and coenzyme Q10 – against neurodegeneration. The book demonstrates the therapeutic potential of ketogenic diets, and highlights the roles of medicinal plants, phytopharmaceuticals, traditional medicines and food nutrients in neuroprotection.Key Features: Explains damage caused by numerous neurodegenerative disorders and the possible protection offered by antioxidants and functional foods. Describes molecular mechanisms of neurodegeneration by oxidative stress, advancing age, diabetes and mitochondrial dysfunctions. Demonstrates protection offered by nutraceuticals, antioxidants, botanical extracts and functional foods. The book contains twenty-three chapters divided into six sections written by leading researchers. This book is essential reading for health professionals, dietitians, food and nutrition scientists and anyone wanting to improve their knowledge of etiology of neurodegenerative diseases.Advanced Statistics in Regulatory Critical Clinical Initiatives is focused on the critical clinical initiatives introduced by the 21st Century Cure…
Act passed by the United States Congress in December 2016. The book covers everything from the outline of the initiatives to analysis on the effect on biopharmaceutical research and development. Advanced Statistics in Regulatory Critical Clinical Initiatives provides innovative ways to resolve common challenges in statistical research of rare diseases such small sample sizes and provides guidance for combined use of data. With analysis from regulatory and scientific perspectives this book is an ideal companion for researchers in biostatistics, pharmaceutical development, and policy makers in related fields.Key Features: Provides better understanding of innovative design and analysis of each critical clinical initiatives which may be used in regulatory review/approval of drug development. Makes recommendations to evaluate submissions accurately and reliably. Proposes innovative study designs and statistical methods for oncology and/or rare disease drug development. Provides insight regarding current regulatory guidance on drug development such as gene therapy and rare diseases.The Toxic Microbiome: Animal Products and the Demise of the Digestive Ecosystem
By Sarah Schwitalla. 2023
Gut microbiomes are dynamic communities varying from population to population and throughout life. In Western societies, a toxic metabolic shift…
of gut microbiomes is a driver and underestimated risk factor for the development of many noncommunicable chronic pathologies. This book identifies the root cause of these deleterious microbial changes. During the last several decades, increased consumption of animal products, coinciding and correlating with global climate change, has been a contributing cause of undesirable gut microbiome changes.Key Features Establishes a connection between poor gut microbiome health and chronic disease and cancer development Demonstrates how animal products and low-fiber diet patterns induce a detrimental metabolic transition of the gut microbiome from a human health-maintaining towards a disease-promoting state Discusses the opportunity of a toxic microbial metabolic signature as a powerful clinical and diagnostic tool to effectively predict chronic disease and cancer development Provides the latest evidence on different strategies to rebuild a healthy microbiome metabolism and effectively prevent noncommunicable diseases and colorectal cancer Documents the gut microbiome benefits of a plant-based dietHandbook of Nutraceuticals and Functional Foods
By Robert E.C. Wildman and Richard S. Bruno. 2020
The field of functional foods along with their bioactive food components has grown tremendously over the past decades. Often guided…
by hypothesis-generating epidemiological observations, discoveries from basic science studies and controlled trials in humans have provided critical evidence to help establish an optimal diet that alleviates chronic disease risk. These advances have also driven efforts by the food and nutraceutical industries to establish and market health claims, formulate extra-value foods, and even generate new health foods for human benefit.Handbook of Nutraceuticals and Functional Foods, Third Edition, compiles the data from experts in the field that potentiates the already established credibility of the earlier editions. In its three-section format, it provides an authoritative summary of the prophylactic and/or medicinal benefits of natural foods and their constituents that are linked to favorable health outcomes. Beginning with an overview of the field and associated regulations, each chapter describes the chemical properties, bioactivities, dietary sources, and evidence of these health-promoting dietary constituents.Features:• Summarizes plant- and animal-based functional foods and their bioactive components• New chapters on cannabidiol and scientific, legal, and regulatory considerations; green tea and nutraceutical applications; and herbal nutraceuticals and insulin resistance• Includes information on functional food beverages including coffee, green tea, and dairy milk• Discusses antioxidant and anti-inflammatory activities of vitamin E, anthocyanins and other (poly)phenolic compounds, and carotenoids• Provides an update on the health benefits and requirements of protein and performance and therapeutic application and safety of creatine.The Goddard Guide to Arthropods of Medical Importance
By Gail Miriam Moraru, Jerome Goddard II. 2019
Covering all major arthropods of medical importance worldwide, this award-winning resource has established itself as a standard reference for almost…
25 years. With the globilization of commerce and the world becoming more intimately connected through the everyday ease of travel, unknown arthropod species are being increasingly encountered. This means access to up-to-date, authoritative information in medical entomology has never been more important. Now in its seventh edition, this book maintains its well-acclaimed status as the ultimate easy-to-use guide to identify disease-carrying arthropods, the common signs and symptoms of vector-borne diseases, and the current recommended procedures for treatment. Includes an in-depth chapter with diagnostic aids to help physicians to recognize and accurately diagnose arthropod-related diseases and conditions more easilyUpdates all chapters with the latest medical and scientific findings, including Zika virus, red meat allergy, new viruses found in ticks, and vaccine development for malaria and dengue feverPresents a greater medical parasitology emphasis throughout Offers electronic downloads containing additional photographs of arthropod-caused diseases and lesions, as well as instructional videos with pest identification aids, basic entomology, and insect and pest ecology.Illustrated throughout with detailed color images to aid identification, The Goddard Guide to Arthropods of Medical Importance, Seventh Edition will remain an essential guide for physicians, public health officials, and pest control professionals.CRC Handbook of Food, Drug, and Cosmetic Excipients
By Susan C. Smolinske. 1992
CRC Handbook of Food, Drug, and Cosmetic Excipients provides a comprehensive summary of toxicological issues regarding inactive ingredients in pharmaceutical…
products, cosmetic products, and food additives. Background information on regulations and labeling requirements for each type of product is provided, and 77 articles critically review human and animal data pertinent to a variety of agents and makes judgments regarding the clinical relevance. The book also identifies at-risk populations, such as neonates, patients with renal failure, and atopic patients. Inactive common pharmaceutical agents and/or foods containing certain ingredients are listed to help physicians counsel hypersensitive patients who must avoid products containing these excipients.Advances in 3D Bioprinting (Series in Materials Science and Engineering)
By Roger J. Narayan. 2024
"3D bioprinting" refers to processes in which an additive manufacturing approach is used to create devices for medical applications. This…
volume considers exciting applications for 3D bioprinting, including its use in manufacturing artificial tissues, surgical models, and orthopedic implants.The book includes chapters from leaders in the field on 3D bioprinting of tissues and organs, biomedical applications of digital light processing, biomedical applications of nozzle-free pyro-electrohydrodynamic jet printing of buffer-free bioinks, additive manufacturing of surgical models, dental crowns, and orthopedic implants, 3D bioprinting of dry electrodes, and 3D bioprinting for regenerative medicine and disease modeling of the ocular surface.This is an accessible reference for students and researchers on current 3D bioprinting technology, providing helpful information on the important applications of this technology. It will be a useful resource to students, researchers, and practitioners in the rapidly growing global 3D bioprinting community.PPG Signal Analysis: An Introduction Using MATLAB®
By Mohamed Elgendi. 2021
This book serves as a current resource for Photoplethysmogram (PPG) signal analysis using MATLAB®. This technology is critical in the…
evaluation of medical and diagnostic data utilized in mobile devices. Information and methodologies outlined in the text can be used to learn the empirical and experimental process (including data collection, data analysis, feature extractions, and more) from inception to conclusion. This book also discusses how introduced methodologies can be used and applied as tools that will teach the user how to validate, test, and simulate developed algorithms before implementing and deploying the algorithms on wearable, battery-driven, or point-of-care devices.Bayesian Designs for Phase I-II Clinical Trials (Chapman & Hall/CRC Biostatistics Series #92)
By Ying Yuan, Hoang Q. Nguyen, Peter F. Thall. 2016
Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose…
or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources. Bayesian Designs for Phase I–II Clinical Trials describes how phase I–II designs can serve as a bridge or protective barrier between preclinical studies and large confirmatory clinical trials. It illustrates many of the severe drawbacks with conventional methods used for early-phase clinical trials and presents numerous Bayesian designs for human clinical trials of new experimental treatment regimes.Written by research leaders from the University of Texas MD Anderson Cancer Center, this book shows how Bayesian designs for early-phase clinical trials can explore, refine, and optimize new experimental treatments. It emphasizes the importance of basing decisions on both efficacy and toxicity.Problems and Solutions in Medical Physics: Radiotherapy Physics (ISSN)
By Kwan Hoong Ng, Ngie Min Ung, Robin Hill. 2018
The third in a three-volume set exploring Problems and Solutions in Medical Physics, this volume explores common questions and their…
solutions in Radiotherapy. This invaluable study guide should be used in conjunction with other key textbooks in the field to provide additional learning opportunities.One hundred and forty-four solved problems are provided in ten chapters on basic physics topics, including: External Beam Therapy Equipment, Photon Beam Physics, Radiation dosimetry, Treatment Planning for External Beam Radiotherapy, and External Beam Commissioning and Quality Assurance.Each chapter provides examples, notes, and references for further reading to enhance understanding.Key features: Consolidates concepts and assists in the understanding and applications of theoretical concepts in medical physics Assists lecturers and instructors in setting assignments and tests Suitable as a revision tool for postgraduate students sitting medical physics, oncology, and radiology science examinationsCure Models: Methods, Applications, and Implementation (Chapman & Hall/CRC Biostatistics Series)
By Yingwei Peng, Binbing Yu. 2021
Cure Models: Methods, Applications and Implementation is the first book in the last 25 years that provides a comprehensive and…
systematic introduction to the basics of modern cure models, including estimation, inference, and software. This book is useful for statistical researchers and graduate students, and practitioners in other disciplines to have a thorough review of modern cure model methodology and to seek appropriate cure models in applications. The prerequisites of this book include some basic knowledge of statistical modeling, survival models, and R and SAS for data analysis.The book features real-world examples from clinical trials and population-based studies and a detailed introduction to R packages, SAS macros, and WinBUGS programs to fit some cure models. The main topics covered include the foundation of statistical estimation and inference of cure models for independent and right-censored survival data, cure modeling for multivariate, recurrent-event, and competing-risks survival data, and joint modeling with longitudinal data, statistical testing for the existence and difference of cure rates and sufficient follow-up, new developments in Bayesian cure models, applications of cure models in public health research and clinical trials.Aquatic Medicinal Plants (Exploring Medicinal Plants)
By Archana Bachheti, Rakesh Kumar Bachheti, Azamal Husen. 2023
The use of medicinal plants in herbal and modern medicine has gained popularity over the last few decades due to…
consumers taking more natural approaches to medicine. Aquatic medicinal plants are rich in bioactive compounds and demonstrate various commercial, nutraceutical, and biological applications. Aquatic Medicinal Plants offers the reader a wealth of information on uses of bioactive components of these plants, along with crucial references, and explains their traditional uses, phytochemistry, and pharmacological properties.Features Provides information on aquatic and semiaquatic medicinal plants and their uses globally. Discusses phytochemical components with the known active constituents and their pharmaceutical applications. This volume in the Exploring Medicinal Plants series is appropriate for scientists, experts, and consultants associated with the exploration of aquatic medicinal plant usage. This book is an essential tool for identifying important aquatic medicinal plants and possibilities for the synthesis or preparation of modern drugs.Mathematical modelling is an important part of nuclear medicine. Therefore, several chapters of this book have been dedicated towards describing…
this topic. In these chapters, an emphasis has been put on describing the mathematical modelling of the radiation transport of photons and electrons, as well as on the transportation of radiopharmaceuticals between different organs and compartments. It also includes computer models of patient dosimetry. Two chapters of this book are devoted towards introducing the concept of biostatistics and radiobiology. These chapters are followed by chapters detailing dosimetry procedures commonly used in the context of diagnostic imaging, as well as patient-specific dosimetry for radiotherapy treatments. For safety reasons, many of the methods used in nuclear medicine and molecular imaging are tightly regulated. Therefore, this volume also highlights the basic principles for radiation protection. It discusses the process of how guidelines and regulations aimed at minimizing radiation exposure are determined and implemented by international organisations. Finally, this book describes how different dosimetry methods may be utilized depending on the intended target, including whole-body or organ-specific imaging, as well as small-scale to cellular dosimetry.This text will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine. The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine Edited by a leader in the field, with contributions from a team of experienced medical physicists, chemists, engineers, scientists, and clinical medical personnel Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history