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Surgery of the Spine and Spinal Cord
By Erik van de Kelft. 2016
This book offers essential guidance on selecting the most appropriatesurgical management option for a variety of spinal conditions, includingidiopathic problems,…
and degenerative disease. While the first part ofthe book discusses the neuroanatomy and biomechanics of the spine, pain mechanisms,and imaging techniques, the second guides the reader through the diagnosticprocess and treatment selection for disorders of the different regions of thespine, based on the principles of evidence-based medicine. I. e. , it clearlyexplains why a particular technique should be selected for a specific patienton the basis of the available evidence, which is carefully reviewed. The bookidentifies potential complications and highlights technical pearls, describingnewer surgical techniques and illustrating them with the help of images andaccompanying videos. Though primarily intended for neurosurgeons, the book willalso be of interest to orthopaedic surgeons, specialists in physical medicine, and pain specialists. Key Diagnostic Features in Uroradiology
By Li-Jen Wang. 2015
This book presents a wealth of images of the different diseases and conditions encountered in the field of uroradiology with…
the aim of enabling the reader to recognize lesions, to interpret them appropriately and to make correct diagnoses. The images have been selected because they depict typical or classic findings and provide a route to lesion recognition that is superior to memorization of descriptions. The imaging modalities represented include CT, CT angiography, CT urography, MRI, MRA, MRU, diffusion-weighted MRI and ADC mapping, dynamic contrast-enhanced MRI, sonography, conventional angiography, excretory urography, retrograde pyelography, cystography, urethrography and voiding cystourethrography. For each depicted case, important imaging features are highlighted and key points identified in brief accompanying descriptions. Readers will find that the book provides excellent guidance in the selection of imaging modalities and facilitates diagnosis. It will be an ideal ready source of information on key imaging features of urinary tract diseases for medical students, residents, fellows and physicians handling these diseases.Pediatric and Adult MRI Atlas of Bone Marrow
By Hakan Ilaslan, Murali Sundaram. 2016
This comprehensive atlas is unique in being devoted to the MRI appearances of bone marrow in the axial and appendicular…
skeleton of adults and children. Normal MRI findings, including common variants and degenerative changes, are first documented. MRI appearances in the entire spectrum of neoplastic and non-neoplastic infiltrative marrow disorders are then presented, with accompanying explanatory text. Among the conditions considered are multiple myeloma, the acute and chronic leukemias, diffuse metastases, diffuse lymphomas, the anemias, polycythemia vera, myelofibrosis, storage disorders, and infections. Characteristic changes to bone marrow following various forms of treatment are also displayed and discussed. The selected images reflect the use of a variety of sequences and techniques, such as fat suppression, and contrast-enhanced imaging.The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease
By Irving M. Shapiro, Makarand V. Risbud. 2013
The intervertebral disc is a complex structure that separates opposing vertebrae, permits a wide range of motion, and accommodates high…
biomechanical forces. Disc degeneration leads to a loss of function and is often associated with excruciating pain. Written by leading scientists and clinicians, the first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies to mitigate the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is devoted to approaches to model normal development and elucidate the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques. The book bridges the gap between the basic and clinical sciences; the target audience includes basic scientists, orthopaedists and neurologists, while at the same time appealing to the needs of graduate students, medical students, interns and fellows.Practical Cell Culture Techniques
By Alan A. Boulton, Wolfgang Walz, Glen B. Baker. 1993
Practical Cell Culture Techniques focuses on the advantages of new tissue culture techniques that enable close and detailed study of…
many nerve cell types. Neuroscience is one of the key areas whose rapid development has been driven by the proliferation of cell culture methodology; some areas of neuroscience, such as glial cell biology and function, now depend almost entirely on cell culture-based research projects. This latest volume of Humana's renowned Neuromethods series provides practical treatment of the new, powerful methodologies and results including: cell culture techniques specifically designed for the novice * the environmental factors that play a role in tissue culturing * cell markers * nutrition requirements of the different cell types * three-dimensional organotypic slice explant cultures * neuronal cultures * cultures of astrocytes, oligodendrocytes, cerebral capillary endothelium, and other cell types. Boulton, Baker, and Walz's new volume on Practical Cell Culture Techniques is sure to be a major resource for everyone-whether expert or novice-involved in studying the central nervous system on the molecular level.Essential Epidemiology
By Penny Webb, Chris Bain, Andrew Page. 2016
The new edition of this popular textbook remains a clear and practical introduction to epidemiology for students in all areas…
of health. By emphasising the role of epidemiology across a broad range of health monitoring and research, it gives students an understanding of the fundamental principles common to all areas of epidemiology. It also integrates the study of infectious and chronic diseases as well as public health and clinical epidemiology. Avoiding complex mathematics, it steps through the methods and potential problems underlying health data and reports, while maintaining a balance of rigour and clarity. The nuts-and-bolts of epidemiology are embedded in the wider international health perspective through recent and classical examples across different areas of health to engage students from a range of backgrounds. Concepts are illustrated with charts and graphs, and end-of-chapter questions test understanding (with answers provided). Online resources include further exercises, slides for teaching and useful weblinks.Sudden Cardiac Death in the Young and Athletes
By Cristina Basso, Gaetano Thiene, Domenico Corrado. 2016
This text atlas focuses on the pathology and molecular genetics of sudden cardiac death in the young and in athletes,…
presenting the state of the art in the field as the basis for development and implementation of more effective prevention strategies, including, ultimately, molecular therapy that will cure the underlying biological defect. A wealth of high-resolution color images, accompanied by clear supporting text, are presented to document the anatomic pathology of the cardiac diseases most frequently responsible for sudden cardiac death in this population, including coronary artery diseases, cardiomyopathies, myocarditis, valve diseases, conduction system abnormalities, congenital heart diseases, and ion channel diseases. The role of the molecular autopsy in overcoming the limitations of morphological investigations and offering new insights and avenues for prevention is explained. The approach is, however, interdisciplinary, with close attention also to epidemiologic and clinical aspects. The authors draw throughout on their experience gained over 30 years in the course of a prospective study carried out in the Veneto Region, North East Italy. This text atlas will be of great value not only for cardiologists but also for geneticists, sports physicians, and residents in cardiology and pathology.Diagnostic Imaging of Emerging Infectious Diseases
By Pu-Xuan Lu, Bo-Ping Zhou. 2016
This book introduces the diagnosis of Emerging Infectious Diseases (EIDs), including newly emerging infectious diseases and also infectious diseases that…
show resistance to present treatments. Radiographic examinations are of great value in EIDs diagnosis, differential diagnosis, treatment efficacy assessment and prognosis evaluation. This book covers severe acute respiratory syndrome (SARS), human avian influenza (H5N1, H7N9), influenza A (H1N1), hand-foot-mouth disease, acquired immune deficiency syndrome (AIDS), viral hepatitis, pulmonary tuberculosis. All seven of these EIDs are associated with high incidence and mortality. This book details the imaging techniques, radiological appearance and characteristics of EIDs, and diagnosis and differential diagnosis of EID-related complications. Considering the unique and in some cases only partially understood nature of EIDs, appropriate space is provided in this book for the detailed explanation of the etiology, epidemiology, pathophysiology, clinical symptoms and signs, laboratory tests, clinical diagnosis and differential diagnosis, prevention, treatment, and prognosis of EIDs. As such, it will be a valuable resource for improving the prevention, diagnosis, and treatment of EIDs. Editors Pu-Xuan Lu and Bo-Ping Zhou are professors at Shenzhen Third People's Hospital, Guangdong Medical College, China.Radiology Illustrated: Gastrointestinal Tract
By Byung Ihn Choi. 2015
Radiology Illustrated: Gastrointestinal Tract is the second of two volumes designed to provide clear and practical guidance on the diagnostic…
imaging of abdominal diseases. The book presents approximately 300 cases with 1500 carefully selected and categorized illustrations of gastrointestinal tract diseases, along with key text messages and tables that will help the reader easily to recall the relevant images as an aid to differential diagnosis. Essential points are summarized at the end of each text message to facilitate rapid review and learning. Additionally, brief descriptions of each clinical problem are provided, followed by case studies of both common and uncommon pathologies that illustrate the roles of the different imaging modalities, including ultrasound, radiography, computed tomography, and magnetic resonance imaging.Pediatric Orthopedic Imaging
By Rebecca Stein-Wexler, Sandra L. Wootton-Gorges, M. B. Ozonoff. 2015
This book is an indispensable reference for pediatric and musculoskeletal radiologists, as well as orthopedic surgeons. It offers in depth…
analysis of pediatric orthopedic imaging, covering normal and aberrant development as well as both common and unusual pediatric disorders. Chapters on the spine, shoulder, elbow, hand and wrist, hip and pelvis, lower extremity, and foot and ankle address site-specific congenital and acquired lesions. Subsequent chapters cover generalized orthopedic diseases such as neurofibromatosis and osteogenesis imperfecta, infectious processes, neuromuscular diseases, musculoskeletal tumors, trauma, and orthopedic procedures. The chapters review associated epidemiology, clinical presentation and evolution, treatment, and differential diagnoses, with in-depht analysis of imaging characteristics. With more than 1800 images, high-quality MRI, CT, and US examples complement the radiographs of a broad variety of musculoskeletal disorders.Statistical Methods for Evaluating Safety in Medical Product Development
By A. Lawrence Gould. 2015
This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of…
clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during medical product development. Each chapter provides sufficient detail to the reader to undertake the design and analysis of experiments at various stages of product development, including comprehensive references to the relevant literature.Provides a guide to statistical methods and application in medical product developmentAssists readers in undertaking design and analysis of experiments at various stages of product developmentFeatures case studies throughout the book, as well as, SAS and R codeMelanocytic Lesions
By Martin C. Mihm, Mai P. Hoang. 2014
Melanocytic Lesions: A Case Based Approach provides a concise yet comprehensive guideline on how to diagnose common as well as…
problematic and challenging melanocytic lesions. In the first 11 chapters, each entity is illustrated by an actual case; followed by discussion of how the diagnosis is reached, of the histologic differential diagnoses and of diagnostic pitfalls and ends with bulleted teaching points Pertinent and up to date references are included at the end of each chapter. The latter chapters cover current microstaging and classification of melanoma, ancillary techniques including immunohistochemistry as well as available molecular assays and molecular targeted therapy. All figures and glass slides of the discussed cases are hosted online for easy viewing and access. Melanocytic Lesions: A Case Based Approach will serves as a useful resource for pathologists, dermatologists and researchers dealing with melanocytic lesions.Handbook of Practical Immunohistochemistry
By Fan Lin, Jeffrey Prichard. 2011
In a conceptually current, quick-reference, Question & Answer format, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions provides standardization of…
the immunostaining process for each antibody and for each staining panel. With links to the authors Immunohistochemical Laboratory website, this volume creates a current and up-to-date information system on immunohistochemistry. This includes access to tissue microarrays (TMA) of over 5,000 tumors to validate common diagnostic panels and provide the best reproducible data for diagnostic purposes. Chapters are presented in a unique Question and Answer format. One table/IHC panel is provided to address each question. A concise explanatory note follows each table/panel to avoid diagnostic pitfalls. Website links are provided throughout to update the massive information in this field, providing the most current knowledge and the potential for live expert consultation. All chapters are written by nationally/internationally recognized experts in the related area ensuring authority and excellence. Comprehensive yet practical and concise, the Handbook of Practical Immunohistochemistry: Frequently Asked Questions, will be of great value for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.Intraoperative Imaging and Image-Guided Therapy
By Ferenc A. Jolesz. 2014
Image-guided therapy (IGT) uses imaging to improve the localization and targeting of diseased tissue and to monitor and control treatments.…
During the past decade, image-guided surgeries and image-guided minimally invasive interventions have emerged as advances that can be used in place of traditional invasive approaches. Advanced imaging technologies such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) entered into operating rooms and interventional suites to complement already-available routine imaging devices like X-ray and ultrasound. At the same time, navigational tools, computer-assisted surgery devices, and image-guided robots also became part of the revolution in interventional radiology suites and the operating room. Intraoperative Imaging and Image-Guided Therapy explores the fundamental, technical, and clinical aspects of state-of the-art image-guided therapies. It presents the basic concepts of image guidance, the technologies involved in therapy delivery, and the special requirements for the design and construction of image-guided operating rooms and interventional suites. It also covers future developments such as molecular imaging-guided surgeries and novel innovative therapies like MRI-guided focused ultrasound surgery. IGT is a multidisciplinary and multimodality field in which teams of physicians, physicists, engineers, and computer scientists collaborate in performing these interventions, an approach that is reflected in the organization of the book. Contributing authors include members of the National Center of Image-Guided Therapy program at Brigham and Women's Hospital and international leaders in the field of IGT. The book includes coverage of these topics: - Imaging methods, guidance technologies, and the therapy delivery systems currently used or in development. - Clinical applications for IGT in various specialties such as neurosurgery, ear-nose-and-throat surgery, cardiovascular surgery, endoscopies, and orthopedic procedures. - Review and comparison of the clinical uses for IGT with conventional methods in terms of invasiveness, effectiveness, and outcome. - Requirements for the design and construction of image-guided operating rooms and interventional suites.Minimally Invasive Surgery in Orthopedics
By Giles R. Scuderi, Alfred J. Tria. 2010
This comprehensive reference serves as a single source for MIS in orthopedics. The editors and contributors are recognized authorities in…
the field who share their insight on how to master challenging techniques. Sections focus on the shoulder and elbow, the hip, the knee, the foot and ankle, the spine, and computer navigation. Readers are guided step-by-step through cutting-edge procedures, and chapters include usage techniques for the latest instrumentation. The text is distinguished by case studies and expert roundtable discussions that address challenging questions and issues in the field. Illustrations and intra-operative photographs further clarify each approach. Orthopedic surgeons, residents, and fellows who want to truly understand MIS will find this thorough text invaluable.Surgical Approaches to the Spine
By Iii, Iv, Robert G. Watkins. 2015
Now is its revised and expanded third edition, including nine new chapters, this step-by-step, state-of-the-art procedural manual covers over 50…
unique surgical approaches for injuries and conditions of the spine. Generously illustrated, various surgical approaches to the cervical, thoracic and lumbar spine are clearly enumerated and described, including anterior, lateral, and posterior approaches and the worldwide movement toward the use of tubular retractors for a multitude of approaches. Written and edited by leaders in the field of spine surgery, this updated edition will be an invaluable resource for orthopedic surgeons, neurosurgeons and sports medicine practitioners alike.Surgical Treatment of Colorectal Problems in Children
By Alberto Peña, Andrea Bischoff. 2015
This superbly illustrated book on the surgical treatment of pediatric colorectal problems focuses in particular on the specific technical maneuvers…
that may be considered key to successful results. The presented management concepts are based on a database comprising over 5000 patients, more than 2300 of whom have been operated on by one of the authors as lead surgeon over the past 30 years. The full range of colorectal disorders in children is thus covered, from cloaca and fistulas to rare presentations. In addition, chapters are included on topics such as prenatal diagnosis, minimally invasive techniques, recent advances in imaging, and a bowel management program for fecal incontinence. Surgical Treatment of Colorectal Problems in Children is eminently a practical book. Clarity, simplicity and applicability are emphasized throughout. The excellence of the illustrations and photographs is a crucial feature and the reader will also have access to instructive videos of procedures.Limb Lengthening and Reconstruction Surgery Case Atlas
By S. Robert Rozbruch, Reggie C. Hamdy. 2015
Consisting of case studies contributed by both domestic and international leaders in the field, this atlas will be an invaluable…
resource for all orthopedic surgeons and researchers and practitioners of limb lengthening, deformity correction and the Ilizarov method. Comprehensive yet accessible, it will cover pediatrics, foot and ankle, trauma and post-traumatic reconstruction, adult deformity, tumor and upper extremity interventions in dedicated sections. Each of the unique cases will include color photographs and radiographs from before, during and after surgery and will follow a consistent chapter structure which outlines a brief clinical history of the case, preoperative problem list, treatment strategy, basic principles, technical pearls and how to avoid and manage complications and subsequent problems. Suggested readings round out each case. A comprehensive presentation of techniques will be featured, including external fixation, internal fixation, combination approaches and fully implantable limb lengthening nails. This case-based approach will be an efficient and thorough way to learn this exciting new frontier in orthopedic surgery.Indirect Action: Schizophrenia, Epilepsy, AIDS, and the Course of Health Activism
By Lisa Diedrich. 2016
The experience of illness (both mental and physical) figures prominently in the critical thought and activism of the 1960s and…
1970s, though it is largely overshadowed by practices of sexuality. Lisa Diedrich explores how and why illness was indeed so significant to the social, political, and institutional transformation beginning in the 1960s through the emergence of AIDS in the United States. A rich intervention--both theoretical and methodological, political and therapeutic--Indirect Action illuminates the intersection of illness, thought, and politics.Not merely a revision of the history of this time period, Indirect Action expands the historiographical boundaries through which illness and health activism in the United States have been viewed. Diedrich explores the multiplicity illness-thought-politics through an array of subjects: queering the origin story of AIDS activism by recalling its feminist history; exploring health activism and the medical experience; analyzing psychiatry and self-help movements; thinking ecologically about counterpractices of generalism in science and medicine; and considering the experience and event of epilepsy and the witnessing of schizophrenia. Indirect Action places illness in the leading role in the production of thought during the emergence of AIDS, ultimately showing the critical interconnectedness of illness and political and critical thought.The Wondrous Story of Anesthesia
By Edmond I Eger, Lawrence J. Saidman, Rod N. Westhorpe. 2014
Edited and written by an international "who's who" of more than 100 authors, including anesthesiologists, nurse anesthetists, bench scientists, a…
surgeon, and representatives of industry, this text provides a comprehensive history of anesthesia, unique in its focus on the people and events that shaped the specialty around the world, particularly during the past 70 years when anesthesia emerged from empiricism and developed into a science-based practice.