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This is a concise how-to of successfully treating previously deemed "untreatable" retinal and optic nerve conditions with stem cell therapies.… Based on the results of 11 years of experience treating approximately 600 patients, this text will serve as a template for others to develop similar stem cell based treatments in their specialty. Author, Jeffrey N. Weiss, MD is specifically poised to offer dependable insight on stem cell surgery for both the retina and the optic nerve, having performed the first retinal stem cell surgery in 2010, with Institutional Review Board (IRB) approved studies that are registered with the National Institute of Health (NIH), and listed on ClinicalTrials.gov. Featuring all original work from Dr. Jeffrey Weiss's specialization in stem cell ophthalmology, this book is primarily written for ophthalmologists, but structured so that specialists across disciplines can take the model presented and create their own studies and clinical trials using stem cell therapies.
Serving as a practical guide to the ocular imaging modalities that are currently available to eye care providers for the… care of glaucoma patients, this book provides information on advances in ocular imaging and their applications in the diagnosis and management of glaucoma. Each chapter introduces the imaging modality, highlight its strengths and weaknesses for clinical care, and discuss its integration into the clinical examination and decision-making process. The chapters also provide an in-depth description of the interpretation of images from each imaging modality. When appropriate, the chapters will summarize past and ongoing research and propose future research directions and clinical applications. This title will appeal to ophthalmologists and optometrists at all levels, from trainees to experienced clinicians looking to learn new and important information.
Up to date, easy to use, and well-illustrated,Clinical Manual of Contact Lenses, 5th Edition, helps both students and practitioners fit,… evaluate, and troubleshoot contact lens issues in everyday practice. Written by renowned experts in the field, this practical guide is designed for quick access to key information, and includes sample cases, nomograms, and proficiency checklists that summarize and emphasize important points. Thoroughly revised content ensures you'll have the most current guidance on rigid gas permeable lens design and fitting, soft lens problem solving, orthokeratology, bifocal correction, and much more.
Written by internationally renowned experts, the 3rd edition of this six volume textbook provides detailed practical guidance and advice on… the diagnosis and management of the complete range of ocular cancers. Supplying the reader with state-of-the-art knowledge required in order to identify these cancers early and to treat them as effectively as possible, this book is divided into six volumes: Basic Principles, Eyelid and Conjunctival Tumors, Orbital Tumors, Uveal Tumors, Retinal Tumors, and Retinoblastoma. The information presented enables readers to provide effective patient care using the latest knowledge on ophthalmic oncology and to verify diagnostic conclusions based on comparison with numerous full-color clinical photographs from the authors' private collections, histopathologic microphotographs, imaging studies, and crisp illustrations. Clinical Ophthalmic Oncology's clinically focused and user-friendly format allows for rapid retrieval of information in daily practice and is written for residents, fellows, and any physician involved in the care of patients with ocular or orbital malignancies. Additionally, this edition adds several hundred new images to improve comprehension of procedures and techniques. This volume discusses everything from the differential diagnosis and evaluation to orbital imaging and management.
This unique book focuses solely on educating aesthetic practitioners on how to best avoid complications. Should complications occur, the text,… alongside high quality images and supplementary video, details how best to deal with them in terms of the patient’s findings, individual anatomy, and emotional state. Avoiding and Managing Complications in Cosmetic Oculofacial Surgery is divided into four sections for ease of use: meticulous preoperative planning, including proper patient selection; potential intraoperative complications and their management; postoperative complication-specific management such as lower eyelid retraction; and special topics including scar management, crease asymmetry, and complications of other periocular surgery and non-surgical procedures.Drawing on the vast experiences of the volume editors as oculofacial surgeons as well as the varied experiences of the contributors from facial plastics and dermatology this book provides a useful and vital tool for aesthetic practitioners in any specialty.
This volume of the series Springer Briefs in Space Life Sciences explains the physics and biology of radiation in space,… defines various forms of cosmic radiation and their dosimetry, and presents a range of exposure scenarios. It also discusses the effects of radiation on human health and describes the molecular mechanisms of heavy charged particles’ deleterious effects in the body. Lastly, it discusses countermeasures and addresses the vital question: Are we ready for launch? Written for researchers in the space life sciences and space biomedicine, and for master’s students in biology, physics, and medicine, the book will also benefit all non-experts endeavouring to understand and enter space.
Offering authoritative, concise coverage of today’s neuro-ophthalmology, Walsh & Hoyt's Clinical Neuro-Ophthalmology: The Essentials distills the most vital information from… the esteemed three-volume parent text, Walsh & Hoyt’s Clinical Neuro-Ophthalmology, into a convenient, single-volume resource. A practical and intuitive organization provides quick access to the essential information you need to effectively evaluate and manage the majority of neuro-ophthalmic conditions. Written by leaders in the field, this must-have fourth edition is a comprehensive, succinct, and clinically relevant reference for your everyday practice.
Known for its consistent, authoritative content and presentation, Shields Textbook of Glaucoma is the premier succinct and clinically focused text… on the medical and surgical management of glaucoma. This full-color, easy-to-use reference offers a rational approach to every aspect of the field, including rare glaucomas, and presents a total care plan for the patient. The seventh edition brings you fully up to date with all that’s new in this rapidly changing field with new chapters, newly colorized line drawings, and an updated design for faster reference.
This book aims to cover the important pediatric ophthalmic diagnoses that present in the emergency room. A collaborative work of… experienced experts, it describes the history, examination, testing, epidemiology, pathogenesis, treatment, and prognosis for a variety of disorders. Richly illustrated, the book off ers an invaluable tool for all specialists and trainees entrusted with the care of children presenting with ocular conditions.Across 17 comprehensive yet concise chapters, this book provides an overview on a number of typical pathologies, including trauma, infections, inflammations, and tumors. Organized into five sections, each chapter is written to relay broad insight into the common ophthalmic conditions that may bring a child in for an acute healthcare visit. Additionally, skillfully written text is further supplemented by many high-quality images, including clinical photographs, fundus images, radiographs, and intraoperative photos. Pediatric Ophthalmology in the Emergency Room meets the market need for a resource on this specific topic designed for trainee instruction. It is a valuable text for medical students, residents, and fellows, as well as anyone involved in the urgent or emergent care of children, including ER physicians, ophthalmologists, optometrists and other personnel.
This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations… in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervention. A number of innovative areas of research are considered, including the role of the immune system, inflammation and oxidative stress in the development of microvascular alterations. Lastly, it examines the availability of recent non-invasive methods for the evaluation of small resistance artery morphology in the retina, which in the near future may provide a useful tool for the stratification of cardiovascular risk and even for clinical decisions regarding drug treatment, thus providing physicians with a clinically relevant instrument for improving and optimizing the management of hypertensive and diabetic patients. The book provides valuable, clinically relevant information for specialists (cardiology, internal medicine, and endocrinology) and general practitioners, and also offers novel and stimulating data to basic and clinical researchers.
This Atlas provides many beautiful images obtained with state-of-the-art technologies, including optical coherence tomography (OCT), OCT angiography, fundus autofluorescence, and… wide-field fundus imaging, as well as traditional images and fluorescein/ICG angiograms. Gathered at the world’s largest High Myopia Clinic, the images are based on the long-term follow-up data of more than 6,000 patients from Japan and abroad. Recent advances in imaging technologies have yielded many new observations and allowed us to detect new lesions, e.g. myopic traction maculopathy (or macular retinoschisis) and dome-shaped macula. An especially interesting aspect: the images obtained by ‘3D MRI of the eye’ and ‘ultra wide-field OCT’ to visualize staphylomas. These techniques were established by the editor’s group and make it possible to record the entire shapes of the eye, offering a scan width of up to 23 mm and scan depth of 5 mm. They have since been used to visualize posterior staphyloma, which was previously impossible to view because it spanned such a wide range of the eye. In addition, readers will learn what types of eye deformity occur in pathologic myopia and how they damage the macula/optic nerve. With this Atlas, readers will learn how to accurately diagnose each lesion of pathologic myopia, how eye deformity causes blinding complications, and how to identify patients with a poor prognosis. In short, it provides essential information that can’t be found elsewhere.
This book reviews the current state of ocular drug therapy and future therapeutic opportunities for a wide variety of conditions,… including Age-related Macular Degeneration, Diabetic Retinopathy and Macular Edema, Glaucoma, and Inherited Retinal Diseases.Retinal diseases are major contributors to moderate or severe vision impairment in adults aged 50 years and older. The respective patient populations for many of these indications is expected to significantly increase as the world population continues to grow older. An improved understanding of the etiological underpinnings of ocular degenerative diseases over the past decade has significantly bolstered ophthalmic drug discovery.In this volume, contributions from leading experts explore the unique challenges faced for ocular drug discovery and delivery providing the reader with detailed information on ocular pharmacokinetics, in vitro, ex vivo and in vivo models for retinal disease pathology and emerging gene therapy treatments. The book is intended for all researchers and clinicians who wish to increase their knowledge on the latest findings in ocular drug therapy.
This book provides an expert overview of all aspects of ophthalmic care in clinical practice. Areas such as External eye,… Cornea and conjunctiva, Glaucoma, Cataract, Macular degeneration and Diabetic retinopathy and retinal vascular events are discussed throughout the chapters. Essentials in Ophthalmic Practice will be a go-to guide for ophthalmologists, optometrists, orthoptists, ophthalmic nurses, ophthalmic technicians and other allied health professionals in their busy day-to-day practice.
When all is well with our eyes, most of us take them for granted. But when our vision is blurred… or our eyes are itchy and watery, it's hard to concentrate on anything but our eyes. In The Eye Book, three eye care specialists present a comprehensive reference to help readers care for their eyes and protect their vision, with special attention to changes and diseases that occur in the adult years. After detailing how the various parts of the eye work together so we can see, the authors review everything that can go wrong—from myopia, hyperopia, and astigmatism to the major disorders of cataracts, glaucoma, and age-related macular degeneration. They also thoroughly describe each part of the eye and the problems that can develop, from the irritation of itchy eyelids and conjunctivitis to emergency situations such as a detached retina. They describe the signs and symptoms of all these problems and how to deal with them, including when to apply a warm compress—and when to head to the emergency room. Medical and surgical treatment of both minor eye irritations and major diseases are explained in detail, so readers know where to turn and what to expect. The authors also tell readers what happens during an eye examination and how to recognize an eye emergency. They explain all about eyeglasses, including the various kinds of bifocals, and describe the care and maintenance of contact lenses in a way that makes wearing them a viable option for anyone who wishes to do so. They detail the special concerns of people with systemic diseases such as diabetes and indicate how common medications—from antibiotics and antidepressants to tamoxifen—affect the eyes. The pros and cons of refractive surgery are discussed, as are the special problems of people with low vision. An appendix lists medications used to treat eye conditions and the side effects of those medications. The book is fully illustrated with fifty-five line drawings and includes a symptoms index that will direct readers to sections of the book which describe the possible causes of the specific symptoms they are experiencing.
This landmark book is the most extensive and complete oculofacial plastic surgery guide available in the market. Updated and broadened… from the three previous editions, it includes advances in the use of surgical navigation systems, and new techniques and treatments for diseases involving the eyelid, orbital and lacrimal system.Organized across 11 sections of in-depth, expertly written text, Smith and Nesi’s Ophthalmic Plastic and Reconstructive Surgery, Fourth Edition has taken the best of the field’s classic reference text and expanded upon it. Detailed chapters cover a multitude of topics relating to various ocular surgeries, pediatric considerations, ocular traumas, and anatomy.Supplemented with a myriad of high-quality illustrations, Smith and Nesi’s Ophthalmic Plastic and Reconstructive Surgery, Fourth Edition is an indispensable reference for oculoplastics surgeons and physicians in other fields.
This volume details different laboratory techniques used to develop regenerative therapies that help treat corneal blindness. Chapters guide readers through… methods and protocols on optimal cell culture conditions, gene-editing techniques, multiple types of scaffold for corneal regeneration, how to evaluate the success of these therapies, and cell and material characterization techniques. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Corneal Regeneration: Methods and Protocols aims to be useful for new and experienced laboratory researchers working on different aspects of corneal regeneration.
This book provides comprehensive and up-to-date information on diagnosis, medical and surgical treatments for pediatric retinal vascular conditions, which are… leading causes of childhood blindness throughout the world. Experienced ophthalmologists in the field discuss basic knowledge about these diseases and practical aspects of management such as exam under anesthesia, diagnostic approaches including spectral-domain hand-held optical coherence tomography (OCT) and OCT angiography. The reader will learn about the recent advances in medical and surgical treatments for pediatric retinal vascular diseases. The surgical treatments, anti-VEGF injections, laser photocoagulation and lens sparing vitrectomy are explained step-by-step and can be observed in several videos.Both the general ophthalmologist who cares for children with retinal diseases and the specialist (pediatric ophthalmologists and vitreoretinal surgeon) will find this book to be an informative resource in providing best care for children with pediatric retinal vascular conditions.
This surgical manual provides a step-by-step guide to various surgical procedures for patients with thyroid eye disease (TED). The key… surgical steps are covered in detail, with intra-operative photographs. The manual addresses all aspects of TED, including the basic anatomy, surgical preparation, evaluation of imaging, and surgical procedures. TED is commonly encountered by oculoplastic surgeons and general ophthalmologists in their daily practice, and restoration of the normal appearance is vital to patients and their families. Surgical treatments for TED include basic oculoplastic surgery, complex eyelid surgery, strabismus surgery, orbital surgery, and aesthetic procedures. All of the contributing authors are eminent experts with vast experience in treating TED. High-resolution images will help readers understand the key surgical steps, and are combined with a minimal amount of text, reflecting the book’s focus on surgical technique. Offering a complete guide that contains all relevant surgical knowledge on TED, presented in a highly practice-oriented format, the book is a must-read for every surgeon whose work involves managing TED.
The book discusses all aspects of choroidal neovascularization (CNV), including the basics, clinical conditions associated with CNV, clinical trials related… to CNV, future directions and rehabilitation. The first section covers the pathogenesis, proposed mechanisms, disease models, histopathology and electronmicroscopy. The next section explores CNV secondary to various clinical conditions, such as age-related macular degeneration (AMD), myopia, and less common conditions like choroidal osteoma. The book also covers clinical features, imaging characteristics, and treatment approaches, as well as clinical trials in CNV conditions with recent updates. Lastly, it features chapters on stem cell therapy, gene therapy, new molecules, and lasers, as well as a section on rehabilitation, which addresses home monitoring and low vision aids. This book is intended for retina specialists, retina fellows and general ophthalmologists.
The iris is a circular, pigmented tissue that separates the anterior chamber of the eye from the posterior chamber. It… has a crucial role on controlling the amount of the light entering the eye through its central opening “the pupil".The Iris has multiple important functions that support and provide image clarity on the retina. However, it is a largely neglected part of the eye, compared to the cornea lens, retina, and optic nerve, and has not been focused on in a comprehensive way until now.The Iris: Understanding the Essentials, combines different aspects of scientific information from a variety of fields, such as anatomy, histopathology, molecular biology, electron microscopy and other diagnostic modalities. Each chapter will include pearls and summary points, and this multi-disciplinary approach helps the clinician diagnose and treat the large variety of diseases that affect the iris, with the main emphasize on pigmentary pathological changes that can affect the color of the eye.Written as a reference review book for universities, practicing ophthalmologists, Ophthalmology residents, pharmaceutical companies and diagnostic equipment manufacturing companies this book summarizes the information in an easy-to-use manner to help the reader better understand the iris, iris structure, physiology and function.