Title search results
Showing 1 - 20 of 2464 items
History of Cenozoic Mammals from South America: A New Model (Springer Earth System Sciences)
By Federico Agnolin. 2024
The Cenozoic history of South America faunas mainly rests on the evidence yielded by the study of fossil mammals. Following…
the seminal work of William D. Matthew, George G. Simpson established the slogan “Splendid Isolation” for describing the evolutionary history of South American faunas. He envisaged South America (as well as other Southern Hemisphere landmasses) as dead ends in the evolution and geographical expansion of animals and plants that since the Mesozoic come in successive migratory waves from the North.More than 40 years passed away from the last important contribution by Simpson (1980). Since then, in spite to the exponential increase in biological, paleontological and geological knowledge, and an incredibly new number of fossils, his scheme remained almost unpolluted and most recent books regarding the palaeobiogeography of South American vertebrates follow this paradigm nearly without criticism.However, the factthat South America was joined to Africa, Australia, Antarctica and India during most of the Cretaceous, and that it was still connected Australia (via Antarctica) and probably Africa up to the Paleogene, together with the large number of shared biotic components between these landmasses, point in favor of a different paleobiogeographical scenario.The book aims to demonstrate that during the Paleogene (and most of the Neogene) the nature and evolutionary history of South American vertebrates is by far much more intricate than previously envisaged. As will be shown, new evidence suggests that southern landmasses may have played an important role in the early evolution and radiation of extant mammal clades. This book is not written to conform with the ideal of a technical manual or a review, and is not carried forward to collect all that has been said before. The main goals are to criticize the current Palaeobiogeographic Model of Vertebrate Settlement of South America, and to propose a new vision based on the evidence provided by the natural world in the last decades.My Life with Diabetes
By Jan De Vries. 2003
The ever-growing problems of diabetes and hypoglycaemia are addressed clearly in this long-awaited book by Jan de Vries, who is…
himself a diabetic.The renowned healer points the possible cause and misunderstandings of the condition and advises authoritatively on its management. MY LIFE WITH DIABETES discusses dietary management and the natural ways to approach diabetes. As the responsiblity for the condition ultimately lies with the patient, this book will be of great value to those who are directly affected, as well as to the friends and families of diabetics, in helping them fully understand the facts relating to diabetes. The book succinctly assists diabetics in finding their way to better health and describes the many natural methods that can be used to control high and low blood sugar levels. It also guides patients who are involved in long-term treatment, indicating how they can overcome related problems using complementary methods. Offering a wealth of direct and uncomplicated advice, MY LIFE WITH DIABETES is an invaluable addition to an acclaimed series of health care titles by deVries.Descubre fascinantes datos y curiosidades sobre los animales que habitaron la Tierra hace millones de años y sorprende a tus…
amigos y familia.¿Sabías que el dinosaurio más grande que ha existido media tanto como cuatro camiones de bomberos uno detrás de otro? ¿O que el más pequeño pesaba menos que una cucharita de azúcar? ¿Quieres saber cuánto medían las alas del reptil volador más grande jamás descubierto? Sumérgete en las páginas de este divertido libro sobre dinosaurios y descubre todo sobre estas criaturas prehistóricas: cuánto medían las garras del Therizinosaurus, qué dinosaurio tenía el cerebro más pequeño, cuál tenía los dientas más afilados y ¡mucho más!El regalo perfecto para saciar el apetito de saber de los niños de un modo divertido: - Contiene más de 1000 curiosidades en formato de pregunta y respuesta.- Escrito de forma clara, con explicaciones entretenidas e impresionantes imágenes generadas por ordenador.- Con estadísticas alucinantes explicadas por medio gráficos y comparaciones visuales para entender los datos de forma fácil.Un divertido libro ilustrado para niños de 9 años o más, repleto de sorpresas y curiosidades alucinantes para que los jóvenes lectores descubran el maravilloso mundo de los dinosaurios.------------------------------------------Astonish your friends and family with this incredible collection of mind-boggling facts about the scariest animals ever to walk the Earth.Did you know that the largest dinosaur was four times longer than a fire engine but its babies were the size of geese? Or that the smallest dinosaur weighed less than a teaspoon of sugar? Or that the largest flying reptile was as tall as a giraffe with wings the size of a fighter jet? This fascinating first dinosaur book for kids is packed with bite-size nuggets of unbelievable information. Find out which dinosaur had the sharpest teeth, the longest claw and the smallest brain.Dive into the pages of this kids dinosaur book to discover: - 1,000 jaw-dropping, mind-blowing facts to wow your family and friends.- Stunning CGI images to convey statistics in an intuitive way that kids can understand.- Factfile spreads are packed with infographics and key facts on all kinds of prehistoric life.- Photo stories feature the world's spectacular fossils, from dinosaur footprints and nests to complete skeletons.- Fun, accessible text written to excite and entertain children and adults alike.Discover the fastest, the slowest, the deadliest, and the downright weirdest dinosaurs ever to roam the planet, in this dinosaur gift book for children aged 9+.Taxonomists specializing in different groups once based phylogenetic analysis only on morphological data; molecular data was used more rarely. Although…
molecular systematics is routine today, the use of morphological data continues to be important, especially for phylogenetic placement of many taxa known only from fossils and rare or difficult to collect species. In addition, morphological analyses help identify potential biases in molecular analyses. And finally, scenarios with respect to morphology continue to motivate biologists: the beauty of a cheetah or a baobab does not lie in their DNA sequence, but instead on what they are and do! This book is an up-to-date revision of methods and principles of phylogenetic analysis of morphological data. It is also a general guide for using the computer program TNT in the analysis of such data. The book covers the main aspects of phylogenetic analysis and general methods to compare classifications derived from molecules and morphology. The basic aspects of molecular analysis are covered only as needed to highlight the differences with methods and assumptions for analysis of morphological datasets.Nutrition and Diabetes: Pathophysiology and Management
By Emmanuel C. Opara and Sam Dagogo-Jack. 2019
Diabetes occurs at such an alarming rate that it can be described as a global epidemic. Following its predecessor, Nutrition…
and Diabetes: Pathophysiology and Management, Second Edition, is a comprehensive resource that describes various factors that drive the accumulation of excess body weight and fat resulting in obesity. The book discusses the metabolic aberrations found in obesity and how they lead to the association of obesity with diabetes. This new edition highlights the role played by diet and the interrelationships in the metabolism of key nutrients in the pathogenesis of obesity and diabetes which provides the scientific basis for treatment and management approaches.Features Highlights the role of nutrition in the pathogenesis of obesity and diabetes Organized logically into two easy-to-use sections - Pathophysiology and Management of Obesity and Pathophysiology and Treatment of Diabetes Features emerging therapeutic approaches for management of obesity and diabetes Discusses experience in the management of obesity and diabetes in developing countries Presents challenges in insulin therapy and provides guidelines to overcome them The first section of the book retains key topics from the previous edition and contains new chapters including genetic determinants of nutrient processing; fat distribution and diabetes mellitus; combined effect of diet and physical activity in the management of obesity; pharmacologic treatment of obesity; and the role of gut microbiota in the pathogenesis and treatment of obesity. The second section features updated versions of most of the other chapters in the first edition comprising a modified chapter on oxidative stress and the effects of dietary supplements on glycemic control in Type 2 diabetes. In addition, new chapters are added in this section and include the contribution of iron and transition metal micronutrients to diabetes; role of microbiota in the pathogenesis and treatment of diabetes; primary prevention of Type 2 diabetes; and the pathophysiology and management of Type 1 diabetes.The Low-Carb Diabetes Cookbook: 100 delicious recipes to help control type 1 and reverse type 2 diabetes
By Dr David Cavan, Emma Porter. 2018
You can reverse pre-diabetes and type 2 diabetes when you change how you eatInternational diabetes expert David Cavan has teamed…
up with food writer and type 1 diabetic Emma Porter to create 100 low-carb, healthy-fat recipes to help reverse type 2 diabetes and prediabetes, and control type 1 diabetes as part of a healthy lifestyle. From simple breakfasts and tasty snacks to indulgent dinners and healthy desserts the authors will help you take control of your health and cook meals the whole family will enjoy. The recipes also help manage type 1 diabetes more effectively.Recipes include:Baked eggs in avocado with roasted fennel and tomatoes One-pan blueberry pancake Roasted aubergine and garlic salad with olive oil, basil and tomatoMexican-style fajitasNutty mushroom risotto with bacon Slow-roasted salt and pepper pulled pork Orange and almond cakeCherry, chocolate and coconut cream ice lolliesThe Fossil Detectives: Discovering Prehistoric Britain
By Douglas Palmer, Hermione Cockburn. 2008
Fossils provide us with a tantalizing glimpse of Britain's prehistoric past and hold the key to unlocking the secrets of…
life's history and evolution. Since the appearance of primitive organisms in Britain more than a billion years ago, oceans, deserts, swamps and vast mountains have come and gone in our corner of western Europe; forests of long-extinct trees, flowers and grasses have covered the land, and dinosaurs and other strange creatures have roamed across it. How do we know? The evidence is all around us - in the rocks and fossils that lie beneath the landscape.In this highly informative and practical book, which accompanies the BBC series, presenter Hermione Cockburn and renowned palaeontologist Douglas Palmer take an in-depth look at the most exciting fossil stories from around the country. When and why were dinosaur fossils first discovered in Britain? How was the biggest fish ever to have swum in the sea unearthed near Peterborough? What do modern medical techniques have to offer fossil hunters?Packed with colour photographs and illustrations, Fossils Detectives is full of surprising facts and features. And for those who want to try their hand at some fossil detecting of their own, the book includes an extensive regional gazetteer of fossil-hunting sites and places to visit, and guidance on identifying your fossil finds.Get ready for some time travel around Britain, with the Fossil Detectives!Around 1.4 million people in the UK today have diabetes, and at least a million more may have diabetes and…
not know it. According to the World Health Organisation the number of diabetes sufferers worldwide is set to double in the next 25 years. It's serious and progressive and there is no known cure. However, life with diabetes can be very fulfilling. Just look at sports stars like Steve Redgave, winner of 5 Olympic gold medals. Written in association with Diabetes UK, this comprehensive guide answers all the key questions, from how to spot the symptoms, who is most at risk, what treatments are available and how diabetes will affect you diet and lifestyle. Dr Hillson tackles the common anxieties and provides invaluable information for all those with diabetes - whether newly diagnosed or longstanding - their families and friends.Dino Dana: Dino Field Guide
By J. J. Johnson, Christin Simms, Colleen Russo Johnson. 2020
A Dino Dana Field Guide of Dinosaurs for Kids (Ages 8-12)“This field guide is great for new and old dinosaur…
lovers. It alphabetically introduces dinosaurs and information about when and where they lived along with other tidbits about them. It is good for fun reading and can be used in homeschooling.” ―JustaBXMomNominated for Four Daytime Emmy® Awards#1 Bestseller in Children's Fossil BooksFun facts about dinosaurs for kids. Did you know that the brachiosaurus was the tallest dinosaur that we know of today? That the kosmoceratops had fifteen horns and hooks on its head? That the spinosaurus is the only known dinosaur to spend most of its time swimming? Discover this and much more in Dino Dana: Dino Field Guide.Dino Dana's field guide for your child. Fans of the Amazon Prime TV show Dino Dana will be so excited to have a Dino Field Guide of their own, put together by the incredible show's creator and executive producer, J. J. Johnson. Full of colorful illustrations and fascinating science facts, this dinosaur book is sure to amaze any young dino enthusiast.A great science book for kids. This book for children is perfect for any kid who likes history and science. In the Dino Dana field guide, your kids learn:Which time period each dinosaur lived inHow big the dinosaurs wereWhat kinds of things dinosaurs ate and did each dayAnd so much moreKids who like cool dinosaur books like Dinosaurs, National Geographic Little Kids First Big Book of Dinosaurs, The Big Book of Dinosaurs, or The Dinosaur Book will love Dino Dana: Dino Field Guide.Put your dinosaur knowledge to the test with this brilliant quiz book for kids!Introducing Dinosaur Knowledge Genius! - a brilliant…
quiz book packed with over 80 topics on the fascinating prehistoric world of dinosaurs. Which were the most fearsome predators? How big were the most gigantic plant-eaters? Why did so many dinosaurs have frills, crests, or spikes? Did dinosaurs really lay eggs? Which ones had feathers? If you want to know the answers, then this may be the book for you! Take on this brain-busting challenge about prehistoric life.This dinosaur quiz book for children aged 9-12 offers: - Plenty of quiz questions throughout the book to put your knowledge to the test.- Interactive &“Test Yourself&” panel lists with three levels of difficulty - starter, challenger, and genius.- Impressive dinosaur graphics that jump out at you on every page.- A variety of fun facts, picture puzzles, and quiz questions to keep kids entertained and engaged.As you hop from one dinosaur species to the next, you will learn all about the fascinating prehistoric world in this entertaining quiz book for kids and the whole family to enjoy. The pages are packed with eye-popping pictures and the "Test Yourself" panels list the type of dinosaur you&’re looking for on the page. With three levels of difficulty, the challenge gets harder from Starter to Challenger and the truly tricky Genius category. There's a fun fact with every picture to give a helpful clue.At DK, we believe in the power of discovery. So why stop here? Why not put your general knowledge to the test with other books in the Knowledge Genius series? Try General Knowledge Genius! to learn about everything, explore the animal world with Animal Knowledge Genius! or explore our planet with Earth Knowledge Genius!The Invention of Prehistory: Empire, Violence, and Our Obsession with Human Origins
By Stefanos Geroulanos. 2024
“[A]n incisive and captivating reassessment of prehistory . . . In lucid prose, Geroulanos unspools an enthralling and detailed history…
of the development of modern natural science. It’s a must-read.” —Publishers Weekly, starred review “An astute, powerfully rendered history of humanity.” —Kirkus Reviews, starred review An eminent historian tells the story of how we came to obsess over the origins of humanity—and how, for three centuries, ideas of prehistory have been used to justify devastating violence against others. Books about the origins of humanity dominate bestseller lists, while national newspapers present breathless accounts of new archaeological findings and speculate about what those findings tell us about our earliest ancestors. We are obsessed with prehistory—and, in this respect, our current era is no different from any other in the last three hundred years. In this coruscating work, acclaimed historian Stefanos Geroulanos demonstrates how claims about the earliest humans not only shaped Western intellectual culture, but gave rise to our modern world. The very idea that there was a human past before recorded history only emerged with the Enlightenment, when European thinkers began to reject faith-based notions of humanity and history in favor of supposedly more empirical ideas about the world. From the “state of nature” and Romantic notions of virtuous German barbarians to theories about Neanderthals, killer apes, and a matriarchal paradise where women ruled, Geroulanos captures the sheer variety and strangeness of the ideas that animated many of the major thinkers of the eighteenth and nineteenth centuries, including Jean-Jacques Rousseau, Charles Darwin, and Karl Marx. Yet as Geroulanos shows, such ideas became, for the most part, the ideological foundations of repressive regimes and globe-spanning empires. Deeming other peoples “savages” allowed for guilt-free violence against them; notions of “killer apes” who were our evolutionary predecessors made war seem natural. The emergence of modern science only accelerated the West’s imperialism. The Nazi obsession with race was rooted in archaeological claims about prehistoric IndoGermans; the idea that colonialized peoples could be “bombed back to the Stone Age” was made possible by the technology of flight and the anthropological idea that civilization advanced in stages. As Geroulanos argues, accounts of prehistory tell us more about the moment when they are proposed than about the deep past—and if we hope to start improving our future, we would be better off setting aside the search for how it all started. A necessary, timely, indelible account of how the quest for understanding the origins of humanity became the handmaiden of war and empire, The Invention of Prehistory will forever change how we think about the deep past.Plains Vizcachas: Biology and Evolution of a Peculiar Neotropical Caviomorph Rodent
By Luciano Luis Rasia, Claudio Gustavo Barbeito, Francisco Acuña. 2024
The plains vizcacha (Lagostomus maximus) is a remarkable rodent of the Neotropic given several peculiar aspects of its biology, some…
of them quite unique among rodents or even among mammals. This book gathers specialists studying plains vizcachas from very different approaches, including paleontology, systematics, morphology, physiology, development and conservation. It is divided in two Parts, 1) Evolutionary History, and 2) Morphology, Development and Physiology. It will surely be a required reading for any researcher working with caviomorph rodents, mastozoology of the Neotropics or internal anatomy and physiology of mammals.Thyroid FNA Cytology: Differential Diagnoses and Pitfalls
By Kennichi Kakudo, Zhiyan Liu, Chan Kwon Jung, Mitsuyoshi Hirokawa, Andrey Bychkov, Chiung-Ru Lai. 2023
This is the third edition of a well-received book that recapitulates the thyroid fine-needle aspiration (FNA) cytology. It covers the…
basics and critical principles of thyroid cytopathology, addresses technical aspects, and presents the latest breakthrough events in the field, including the new editions of the WHO classification of thyroid tumors and the Bethesda system for reporting thyroid cytopathology.Thyroid FNA Cytology, The Third Edition is a practical handbook for cytopathologists, pathologists, cytotechnologists, endocrinologists, thyroid surgeons, radiologists, thyroid cancer patients, and their families. This edition covers more topics than the previous editions and invites authors from 20 countries from Asia, Europe, and America. It should serve as an individualized guide to readers practicing in various geographic areas with different medical settings and social resources. The book provides multiple chapters on differential diagnosis and pitfalls to show the unique approaches in many countries. The book will broaden their perspectives and serve as a foundation for further advancement in this field.Flipons: The Discovery of Z-DNA and Soft-Wired Genomes
By Alan Herbert. 2024
Alan Herbert has played a leading part in discovering the biological roles for a high-energy form of DNA twisted to…
the left rather than to the right. Both Z-DNA and the Z-RNA sensing proteins are critical for protecting hosts against both viruses and cancers. The proteins also play critical roles in the programmed cell death of aging cells. Other types of flipons exist and alter the readout of transcripts from the genome, encoding genetic information by their shape rather than by their sequence. Many of these flipons are within repeat elements that were previously considered to be just genomic junk. Instead these genetic elements increase the adaptability of cells by flipping DNA conformation. By acting as digital switches, the different flipon types can alter cellular responses without any change to their sequence or any damage to DNA. These highly dynamic structures enable the rapid evolution of multicellular organisms. The junk DNA in repeats also encode peptide patches that enable the assembly of cellular machines. The intransitive logic involved enhances the chance of an individual surviving a constantly changing environment.Key Features Causes us to rethink how information is encoded in the genome Changes our understanding of how our genome evolved and how we protect ourselves against viruses and cancers while sparing normal cells Shows that high energy forms of DNA, such as left-handed DNA do exist inside the cell Accessible to those in academia and the general public, and speaks to the next generation, encouraging them to find their own path in scientific discovery The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non-Commercial-No Derivative License (CC-BY-NC-ND) 4.0 license.Use your reading superpowers to learn all about dinosaurs.Meet the Dinosaurs is a beautifully designed, high-quality nonfiction reader about everyone&’s…
favorite fascinating animals.The engaging text has been carefully translated into Modern Standard Arabic (MSA). Diacritics are used so children are set up to succeed.A motivating introduction to using essential nonfiction reading skills.Children will love to find out about the biggest, the noisiest, the fastest and the funniest dinosaurs, and impress their friends with fun-to-say dinosaur names.A novel, interdisciplinary exploration of the relative contributions of rigidity and flexibility in the adoption, maintenance, and evolution of technical…
traditions.Techniques can either be used in rigid, stereotypical ways or in flexibly adaptive ways, or in some combination of the two. The Evolution of Techniques, edited by Mathieu Charbonneau, addresses the impacts of both flexibility and rigidity on how techniques are used, transformed, and reconstructed, at varying social and temporal scales. The multidisciplinary contributors demonstrate the important role of the varied learning contexts and social configurations involved in the transmission, use, and evolution of techniques. They explore the diversity of cognitive, behavioral, sociocultural, and ecological mechanisms that promote and constrain technical flexibility and rigidity, proposing a deeper picture of the enablers of, and obstacles to, technical transmission and change.In line with the extended evolutionary synthesis, the book proposes a more inclusive and materially grounded conception of technical evolution in terms of promiscuous, dynamic, and multidirectional causal processes. Offering new evidence and novel theoretical perspectives, the contributors deploy a diversity of methods, including ethnographies, field and laboratory experiments, cladistics and phylogenetic tree building, historiography, and philosophical analysis. Examples of the wide range of topics covered include field experiments with potters from five cultures, stability and change in Paleolithic toolmaking, why children lack flexibility when making tools, and cultural techniques in nonhuman animals.The volume&’s three thematic sections are:· Timescales of technical rigidity and flexibility· Rigid copying to flexible reconstruction· Exogenous factors of technical rigidity and flexibilityThe volume closes with a discussion by philosopher Kim Sterelny.ContributorsRita Astuti, Adam Howell Boyette, Blandine Bril, Josep Call, Mathieu Charbonneau, Arianna Curioni, Nicola Cutting, Bert De Munck, György Gergely, Anne-Lise Goujon, Ildikó Király, Catherine Lara, Sébastien Manem, Luke McEllin, Helena Miton, Giulio Ongaro, Sarah Pope-Caldwell, Valentine Roux, Manon Schweinfurth, Dan Sperber, Kim Sterelny, Dietrich Stout, James W. A. Strachan, Sadie TenpasEnter the prehistoric world for an incredible four-billion year journey in this book for young history and dinosaur enthusiasts.Take children…
on a fascinating journey through history, showing them how and where their favorite dinosaurs came to exist, and how events from billions of years ago are still affecting our natural world today.Packed with dynamic historical content, Prehistoric Worlds combines illustrations and photos to help young historians aged 7-9 learn all about the period that shaped our planet. Meet favorite dinosaurs, from the terrifying T.Rex to the spiky stegosaurus; nurture your inner paleontologist by learning about prehistoric plant and animal fossils; and discover destructive extinction events that changed the world forever.Inside this dinosaur book for children, you&’ll find: - A wide range of prehistoric life and its chronology, including plants and animals from this period, and the continental shifts that shaped our world today.- Information on natural history written by palaeontologist and scientist Ashley Hall.- Illustrations and expert CGI imagery showing different types of dinosaur species.Plants flourish, birds evolve, and dinosaurs charge across the pages of this lively and colorful book. From oceans teeming with life to destructive asteroids, children will discover the incredible timeline of prehistoric life that resulted in the world we recognize today.Postdiabetic: An Easy-to-Follow 9-Week Guide to Reversing Prediabetes and Type 2 Diabetes
By Eric Edmeades, Ruben Ruiz. 2024
A proven plan to reverse prediabetes and type 2 diabetes with manageable changes to improve your life.If you are struggling…
with type 2 diabetes, obesity, or hypertension, you should know two important things:1) It is not your fault.2) It is your responsibility to turn things around.The truth is that the hardship caused by type 2 diabetes is fueled by profit-seeking food manufacturers. And while it is easy to place blame on the food industry, it is also important to understand our own roles in creating these circumstances.You might wonder why, if type 2 diabetes is reversible, it is commonly treated as a lifelong condition. The answer might shock you: It is being treated that way because it is profitable to treat it that way. It is a lot more profitable to sell drugs to treat lifelong conditions than to show people how to turn them around.But here's the good news: it doesn't have to be this way.In this book, Eric Edmeades and Dr. Ruben Ruiz give you a solid, step-by-step plan that just might reverse the condition for you. Over the course of 9 weeks, you'll learn how to make subtle changes to your lifestyle and deep changes to your psychology. You'll look at what you eat, when you eat it, and why you eat it. You'll begin to move your body into a primarily fat-burning metabolism and away from your current sugar-burning metabolism, learn more about seasonal eating, and reap the benefits of cyclical eating patterns.By the end of this program, you will have a clear understanding of the way the seasons work in concert with your body, and how you can turn around your type 2 diabetes and maintain a healthy lifestyle.Clinical and Laboratory Medicine Textbook
By Marcello Ciaccio. 2023
This textbook describes several diseases and clinical conditions, from physiopathological mechanisms to main clinical pictures, highlighting the importance of laboratory…
medicine, with the aim to provide the necessary tools for guiding correct laboratory findings interpretation. Indeed, it is now widely recognized that laboratory medicine has a pivotal role in clinical medicine, significantly influencing clinical decisions. Thus, it is crucial to understand and use laboratory data appropriately. This book has the great advantage of describing each topic exhaustively in order to facilitate its understanding. Specifically, it describes both diseases with a high incidence in the population, such as Diabetes Mellitus, Cardiovascular Diseases, Dyslipidemias, and Autoimmune Diseases, as well as rare diseases, such as Hereditary Metabolic Diseases. In addition, unusual topics are treated, such as Clinical Biochemistry of the Mind, as well as hot topics, such as Biological Drugs, Biobanks, Health Technology Assessment, and Omics Sciences. Finally, the book includes a chapter on the new health emergency, the SARS-CoV-2 pandemic. Two appendices are provided at the end of the book: a table summarizing the reference range and decisional cut-off for the main laboratory parameters and instructions on performing a venous blood sample. The book will be an invaluable tool for medical and biomedical students, as well as for practitioners.Practical Management of Thyroid Cancer: A Multidisciplinary Approach
By Ujjal K. Mallick, Clive Harmer. 2023
Written by leading world experts, this third edition embraces the philosophy of international collaboration and disseminates the latest advances and…
transformative changes in the field of thyroid cancer.It provides a global health perspective, striving towards a uniform, equitable, evidence-based, cost-effective, practical, and patient-centred approach with high quality care crossing geographical boundaries. This book covers controversial issues and the most up-to-date management of differentiated, medullary, anaplastic, and rarer types of thyroid cancers together with survivorship issues and the lessons learnt during the Covid-19 Pandemic.The molecular landscape of thyroid cancers has a high frequency of oncogenic driver mutations and a high frequency of gene fusions treatable by new gene-specific systemic therapies. These include dual MAPK (Dabrafenib) / MEK (Trametinib) inhibition in BRAF V 600E mutated Anaplastic Thyroid Cancer, Larotrectinib, Entrectinib for NTRKgene fusion, Selpercartinib, Pralsetinib for RET fusion and mutations. These, newer and Master protocol trials, Tumour Agnostic drug development, Immune Checkpoint blockade and CAR-T therapy etc are discussed.The latest NICE and African Guidelines for Management are included. This would be of interest to readers as well.This book is aimed at thyroidologists of all disciplines, (in training or experts) students, non-specialist clinicians, nursing staff, all the disciplines involved in a multidisciplinary team such as surgeons - Head & Neck or Endocrine and General Surgeons, Oncologists, Endocrinologists, Nuclear Medicine Physicians, Nuclear Medicine Physicists, Radiologists, Pathologists, Specialist Nurses, Geneticists, Clinical Psychologists, Palliative Care Physicians and, in addition to AI in medicine, telemedicine experts, health policy makers, and scientists.