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Preeclampsia: Basic, Genomic, And Clinical (Comprehensive Gynecology And Obstetrics Ser.)
By Shigeru Saito. 2018
This volume is an excellent guide that comprehensively illustrates hypertensive disorders of pregnancy especially preeclampsia in both the…
basic and clinical aspects Preeclampsia is a pregnancy-specific multi-organ disorder and a leading cause of maternal and neonatal mortality The pathophysiology of pregnancy-specific disorders was long unknown but recently many new findings have been reported from the point of view of pathophysiology Furthermore this complication of pregnancy especially preeclampsia is a potent risk factor for chronic conditions such as cardiovascular disease diabetes mellitus kidney disease and hypertension The book is composed of seven parts including genetic background pathology pathophysiology and the latest prediction and treatment of preeclampsia Specific basic topics such as immunological maladaptation placental adenosine signaling and new prediction markers are also expounded by experts Thus it benefits not only obstetricians pediatricians nephrologists diabetologists and cardiologists but also immunologists endocrinologists geneticists pathologists biologists and molecular biologists who are interested in the treatment of hypertension in pregnancyPrediction and Management of Severe Acute Pancreatitis
By Chris E. Forsmark, Timothy B. Gardner. 2015
This volume provides a comprehensive summary of the field, with expert recommendations on prediction and management. It details the recent…
consensus guidelines (2012) updating the definition of pancreatitis and its complications The text thoughtfully summarizes the current prediction models for severe acute pancreatitis, including laboratory, clinical and imaging parameters It also highlights the relative advantages and disadvantages of several of these models Evidenced-based guidelines into medical and surgical management of both the hospitalized and discharged patient are described, with recommendations from expert authors pertaining to various clinical situations. Finally, complications of acute pancreatitis and their management, including the use of cutting-edge minimally-invasive therapies, is discussed. Prediction and Management of Severe Acute Pancreatitis will serve as the fundamental source for those interested in and treating this disease, including practicing gastroenterologists, surgeons, radiologists, intensivists, hospitalists and pathologists.Sertoli Cell Metabolism and Spermatogenesis
By Pedro F. Oliveira, Marco G. Alves. 2015
This book is focused on Sertoli cell physiology and its role in the spermatogenic event. These cells, known as "nurse…
cells", are essential for the normal development of germ cells by offering not only physical support and creating an immune-privileged environment, but also for providing nutritional support. The presence of Sertoli cells promotes the establishment of the appropriate microenvironment so that spermatogenesis may occur. Spermatogenesis maintenance in vivo is highly dependent on the metabolic cooperation established between Sertoli cells and developing germ cells. For many years this metabolic cooperation between testicular cells has been disregarded, but recent advances have highlighted the relevance of these processes for male fertility. Thus, the understanding of the functioning and regulation of these metabolic processes is a crucial step to identify key mechanisms associated with Sertoli cell (dys)function and to enlighten their influence on male fertility.This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses…
on the theme of "Drug delivery systems: advanced technologies potentially applicable in personalised treatments". The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.The Making of Modern Medicine: Turning Points in the Treatment of Disease
By Michael Bliss. 2011
At the dawn of the twenty-first century, we have become accustomed to medical breakthroughs and conditioned to assume that, regardless…
of illnesses, doctors almost certainly will be able to help not just by diagnosing us and alleviating our pain, but by actually treating or even curing diseases, and significantly improving our lives. For most of human history, however, that was far from the case, as veteran medical historian Michael Bliss explains in "The Making of Modern Medicine. " Focusing on a few key moments in the transformation of medical care, Bliss reveals the way that new discoveries and new approaches led doctors and patients alike to discard fatalism and their traditional religious acceptance of suffering in favor of a new faith in health care and in the capacity of doctors to treat disease. He takes readers in his account to three turning points a devastating smallpox outbreak in Montreal in 1885, the founding of the Johns Hopkins Hospital and Medical School, and the discovery of insulin and recounts the lives of three crucial figures researcher Frederick Banting, surgeon Harvey Cushing, and physician William Osler turning medical history into a fascinating story of dedication and discovery. Compact and compelling, this searching historyvividly depicts and explains the emergence of modern medicine and, in a provocative epilogue, outlines the paradoxes and confusions underlying our contemporary understanding of disease, death, and life itself. "Prevention Diabetes Diet Cookbook: Discover the New Fiber-FULL Eating Plan for Weight Loss (Prevention Diets)
By The Editors of Prevention, Ann Fittante. 2007
Nearly 21 million Americans already have diabetes, and at least 54 million adults over the age of 20 are at…
risk. Fortunately, there is good news: Studies have shown that people with pre-diabetes who lose weight and increase their physical activity can prevent or delay the onset of type 2 diabetes—and even return their blood glucose levels to normal. This outstanding cookbook draws on the latest science to make losing weight and getting blood sugar under control easier than ever before.Prevention Diabetes Diet Cookbook features:- a new approach to controlling blood sugar naturally—by eating up to 50 grams of fiber a day (nearlytwice the USDA's recommended daily intake)- easy menu plans that lower daily carb intake to target abdominal fat, a leading risk for the heartdisease that commonly accompanies diabetes- more than 200 great-tasting dishes—from Better-for-You Burritos and Skinny Monte Cristos to fabulous special-occasion desserts—that will satisfy the whole family and completely eliminate the need for separate meals- hundreds of practical tips for living well with diabetesDesigned to bring about steady, permanent weight loss—up to 2 pounds a week until one's goal weight is reached—and filled with inspirational, real-life success stories that illustrate Prevention's trusted advice in action, this is an indispensable book for anyone who has, or is at risk of developing, diabetes.The Diabetes DTOUR Diet: The Revolutionary New Food Cure
By Barbara Quinn, Francine R. Kaufman, The Editors of Prevention. 2009
In just 6 weeks, you can... - Bring your blood sugar into balance - Make those extra pounds disappear -…
Send your energy soaring - And you can do it all with food! Not just any food, but undeniably delicious food featuring the Fat-Fighting 4. This awesome foursome--fiber, calcium, vitamin D, and omega-3s--is the secret to healthy, sustainable weight loss and optimal blood sugar control. Research proves it! But how can you be sure you're getting enough of these supernutrients? It's easy on The Diabetes DTOUR Diet. Just follow the day-by-day plan, and in 6 short weeks, you'll be saying hello to a thinner, fitter, healthier you. DTOUR is tailored to the unique weight-loss needs of those with high blood sugar. Whether you have prediabetes or diabetes--or you want to avoid them--this plan can help you succeed. Stop...fretting over calories, carbs, and fat. DTOUR does the counting for you. All you need to do is eat and enjoy! Yield...to the temptation of French toast, quesadillas, spaghetti and meatballs--even ice cream and pudding! Go...for weight-loss success with daily tips and tools to keep you motivated and on trackPrediction Methods for Blood Glucose Concentration
By Harald Kirchsteiger, John Bagterp Jørgensen, Eric Renard, Luigi Del Re. 2016
This book tackles the problem of overshoot and undershoot in blood glucose levels caused by delay in the effects of…
carbohydrate consumption and insulin administration The ideas presented here will be very important in maintaining the welfare of insulin-dependent diabetics and avoiding the damaging effects of unpredicted swings in blood glucose - accurate prediction enables the implementation of counter-measures The glucose prediction algorithms described are also a key and critical ingredient of automated insulin delivery systems the so-called artificial pancreas The authors address the topic of blood-glucose prediction from medical scientific and technological points of view Simulation studies are utilized for complementary analysis but the primary focus of this book is on real applications using clinical data from diabetic subjects The text details the current state of the art by surveying prediction algorithms and then moves beyond it with the most recent advances in data-based modeling of glucose metabolism The topic of performance evaluation is discussed and the relationship of clinical and technological needs and goals examined with regard to their implications for medical devices employing prediction algorithms Practical and theoretical questions associated with such devices and their solutions are highlighted This book shows researchers interested in biomedical device technology and control researchers working with predictive algorithms how incorporation of predictive algorithms into the next generation of portable glucose measurement can make treatment of diabetes safer and more efficientLipidomics
By Sanjoy K. Bhattacharya. 2017
This volume explores lipidomics through protocols that focus on areas of utility techniques and bioinformatics advancements …
The protocols in this book cover topics such as isolation of specific membranes and specialized fractionation of subcellular compartments and computational and functional analysis of lipid metabolizing enzymes Each protocol also discusses methods of dealing with fractionated organelles--cells to whole organisms Written in the highly successful Methods in Molecular Biology series format chapters include introductions to their respective topics lists of the necessary materials and reagents step-by-step readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls Cutting-edge and comprehensive Lipidomics Methods and Protocols is a useful and valuable resource for biochemists molecular biologists and neuroscientists interested in neurology ophthalmology and vision sciences as well as mass spectrometrists with interest in disease discoveryHormones, Talent, and Career: Unlock Your Hormonal Quotient®
By Johan Bremer, Diana Derval. 2012
The media now regularly feature breakthroughs on the influence of prenatal hormones on the brain and behavior, for instance the…
link to financial performance or risk management. Based on these findings and their own experiments, the authors present the Hormonal Quotient (HQ) as a scientific, holistic and reliable career management and personal development tool for professionals. Eight HQ profiles and their corresponding typical business skills and preferences are presented and enable the reader to benchmark their HQ with peers, design an ideal career plan, build a winning team in business and find the perfect work-life balance. A complimentary website allows readers to easily measure their HQ online. By the author of "The Right Sensory Mix", Berry-AMA Book Prize Finalist 2011.Surgery of the Adrenal Gland
By Carlo Bergamini, Celestino Pio Lombardi, Rocco Bellantone, Andrea Valeri. 2012
This book offers a comprehensive description of the main surgical treatments for adrenal tumors, encompassing both open surgery and laparoscopy.…
Introductory chapters cover surgical anatomy, pathology, the clinical diagnostic pathway, the role of different imaging techniques, and perioperative management. After discussion of general principles of adrenal surgery and instrumentation, individual surgical techniques are described in detail with the aid of step-by-step color photos and schematic drawings. For each procedure, careful attention is paid to indications and contraindications and to the most frequent complications. A further feature is the inclusion of numerous helpful decision-making algorithms for diagnosis and treatment. The text is structured according to the principles of "best practice" and the guidelines on evidence-based medicine and will thus be a valuable tool for practitioners in their clinical work.The Hands-on Guide to Diabetes Care in Hospital
By David Levy. 2016
3 am call: "Mrs X has a blood sugar of 23. Come and deal with it.""I think my insulin pen…
is called something like Solostar."The respiratory doctors started high dose prednisolone, and the patient's glucose is 18. What is the blood glucose target for this patient admitted with an acute coronary syndrome?Do you struggle with common diabetes problems in hospital practice?The Hands-on Guide to Diabetes Care in Hospital is an ideal companion for ward practitioners, providing answers to these and many other practical diabetes problems, helping you to deliver safe and effective care to patients.Using the best current UK and international guidance, The Hands-on Guide to Diabetes Care in Hospital presents succinct guidance on acute diabetes problems, blood glucose management, acute medical and surgical problems commonly complicated by diabetes and insulin and non-insulin agents, as well as preparing for discharge to the community. With top tips, key points, questions to ask, treatment and follow-up advice in each chapter, this is an essential resource for all medical trainees and students who treat diabetic patients. Ward-based nurses, diabetes specialist nurses and pharmacists will also find a lot that is relevant to their practice.The Complete Diabetes Organizer
By Leslie Josel, Susan Weiner. 2013
Is your lack of organization impacting your ability to effectively manage your diabetes? Do you run out of supplies and…
forget endocrinologist appointments? Do you find snacks in your pantry that expired sometime before the insulin pump was invented? Do you struggle to keep track of health-care invoices and payments? Do you succeed at keeping an active health journal for a week or two and then neglect it for a year or two?It sounds like you could use The Complete Diabetes Organizer!Within the pages of this book, diabetes educator Susan Weiner and organizing guru Leslie Josel provide you with dependable strategies and ideas designed to help streamline your diabetes care and simplify your life. From her distinguished career and experience in the fields of diabetes and dietetics, Susan Weiner brings helpful tips and tricks that are guaranteed to ease daily mechanics, promote improved nutrition, and relieve stress caused by disorder and confusion. Certified professional organizer and ADHD Specialist Leslie Josel applies her expertise to the topic of diabetes, with simple, surefire techniques that will allow you to disentangle yourself from the clutches of chronic disorganization.The Complete Diabetes Organizer is your guidebook to maintaining your diabetes with less effort and more confidence, allowing you to focus on enjoying a healthier, stress-free life.Carol Guber's Type 2 Diabetes Life Plan
By Carol Guber, Betsy Thorpe. 2002
If you've been diagnosed with type 2 diabetes, you're probably concerned about a host of health issues and may already…
be thinking of the coming dietary changes. As your doctor probably explained, a good eating plan, low weight, and an active lifestyle are among the most important factors in limiting the disease's impact and in continuing to live a full and healthy life. But you don't know where to begin.Enter Carol Guber, a twenty-year veteran of the food industry who holds a master's in nutrition and is a nationally recognized authority on food and nutrition. When she was diagnosed with type 2 diabetes, she refused to accept the diagnosis lying down. Realizing that she was going to have to approach life in a new and vibrant fashion, Carol launched herself into what she describes as "guerilla warfare" against diabetes. She knew she was in for some changes, having been accustomed to gourmet meals and the finest, richest foods. And she also knew the consequences of ignoring her doctor's advice. With her trademark gusto, she was soon enjoying a whole new menu and working out unabashedly alongside gym babes.Carol tried to choose physical activities that would be fun and dynamic, knowing that she had to enjoy herself as well as engage her mind, body and spirit in order to stay healthy. So she began running on a treadmill. She started to lift light weights. She even took up boxing. After several months, her spirited war on diabetes had helped her lose weight and reduce her glucose by 40 percent. Now she hosts workshops for men and women trying to develop their own diabetes-fighting lifestyle. She likes to say that you have to make a whole new life for yourself-often one that ends up being fuller and more active than you've ever dreamed. In her Type 2 Diabetes Life Plan, Carol shares her encouraging insight, bringing us with her along the path toward a richer and more vital life with diabetes.Going beyond her personal success, Carol provides a complete guide to a medical condition that is becoming increasingly widespread. Covering biology, physiology, genetics, medication, and lifestyle issues, she also offers day-to-day advice for finding the mental stamina to stay active and make healthy dietary selections, even when dining out or away from home. Offering motivation as well as information, Carol Guber's Type 2 Diabetes Life Plan is a true lifeline for all of us living with diabetes from a remarkable woman who's living proof of victory.From the Hardcover edition.Pancreatic Stem Cells
By Juan Domínguez-Bendala. 2009
From the discovery of Pdx1, the first "master gene" of pancreatic development, to the most recent findings on the role…
of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas. It is now widely acknowledged that the therapeutic differentiation of stem cells into pancreatic cells is an ambitious endeavor that will not succeed without a thorough understanding of the molecular processes underlying the native development of the organ. This book, aimed at experts and students alike, offers a comprehensive review of the state of the art in both pancreatic development and regeneration. The many strategies to differentiate adult and embryonic stem cells into pancreatic beta cells are also discussed in the context of potential therapeutic interventions for type I diabetes.Multiple Origins of Sex Differences in Brain
By Yves Christen, Donald W Pfaff. 2012
In theoretical terms sex differences in brains and behaviors of laboratory animals offer the possibility of fascinating scientific studies…
on a range of molecular phenomena such as genomic imprinting DNA methylation chromatin protein modification non-coding DNA potentially resulting in important neuroanatomical and neurochemical sex differences in the brain Such sex differences could arise consequent to exposures to testosterone early in development or to other effects deriving from the Y chromosome However this general subject has been treated with much hyperbole Historically sex differences were assumed to be present where they did not really exist e g with respect to mathematics executive leadership etc etc Under what circumstances do we really care about sex differences in brain and behavior These circumstances concern human maladies whose diagnoses are much different between boys and girls or between women and men Prominent examples discussed in this volume include autism attention deficit hyperactivity disorders and congenital adrenal hyperplasia In fact infant boys are more susceptible than infant girls to a variety of disorders that arise early in development This volume then ends with a consideration of effects of estrogenic hormones on the injured brain and their roles as protective agentsPrimer Effects by Murine Pheromone Signaling
By Sachiko Koyama. 2016
This SpringerBrief provides a concise summary on the chemistry and function of murine pheromones in reproduction It discusses…
mechanisms of action as well as the applicability of these mechanisms to humans The image of pheromones is usually some invisible mysterious chemicals that make people attracted to the opposite sex However pheromones have many functions and one that perhaps is not well known yet is that they affect the reproductive status of others Males pheromones stimulate females reproductive status and vice versa This book will present studies on male mice which is rarely covered and will also discuss trans-generational influences of pheromones The book addresses Professors researchers and students working in animal neurochemistry chemical signaling and reproductive medicineMulti-System Endocrine Disruption
By Yves Christen, Jean-Pierre Bourguignon, Bernard Jégou, Bernard Kerdelhué, Jorma Toppari. 2011
Endocrine disruption is an expanding field due to the numerous chemicals involved and as evidenced more recently the…
variety of homeostatic systems that they can alter throughout life The gathering of experts from all over the world should help to identify health disorders that are possibly or likely related to exposure to endocrine disrupters The research needs have been discussed as well as recommendations prioritizing target groups and following the precautionary principleSugar Crush
By Dr Richard Jacoby, Raquel Baldelomar. 2015
Sugar =Chronic Inflammation + Trauma =Nerve Damage, Pain, and DysfunctionDo you suffer from ailments your doctors can't seem to diagnose…
or help--mysterious rashes, unpredictable digestive problems, debilitating headaches, mood and energy swings, constant tiredness? If so, nerve compression is likely the cause.What Grain Brain did for wheat, leading peripheral nerve surgeon Dr. Richard Jacoby now does for sugar, exposing the shocking truth that a diet high in sugar, processed carbohydrates, and wheat can compress and damage the peripheral nerves of the body, and lead to pain, numbness, and tingling in the hands and feet, as well as a host of related conditions, from migraines, autism, and ALS to gallbladder disease and diabetes.Over the years, Dr. Richard Jacoby has treated thousands of patients with peripheral neuropathy. Now he shares his insights and tells the story of how he connected the dots to determine how sugar is the common denominator of many chronic diseases.Practical and accessible, Sugar Crush breaks down our dangerous addiction to sweets, offering a unique, holistic understanding of the toll sugar and carbs take on the body, and demonstrating how dietary changes can help nerves regain their normal function dramatically.Whether you have diabetes or prediabetes, or are even just concerned about your health, Sugar Crush is the essential guide to knowing the dangers of nerve compression. Complete with dietary advice, the latest thinking on ways to prevent and reverse neuropathy, and a quiz to help you assess your nerve damage, this book will give you the tools you need to quit sugar, calm your nerves, and reclaim well-being.Fixing Sex: Intersex, Medical Authority, and Lived Experience
By Katrina Karkazis. 2008
What happens when a baby is born with "ambiguous" genitalia or a combination of "male" and "female" body parts? Clinicians…
and parents in these situations are confronted with complicated questions such as whether a girl can have XY chromosomes, or whether some penises are "too small" for a male sex assignment. Since the 1950s, standard treatment has involved determining a sex for these infants and performing surgery to normalize the infant's genitalia. Over the past decade intersex advocates have mounted unprecedented challenges to treatment, offering alternative perspectives about the meaning and appropriate medical response to intersexuality and driving the field of those who treat intersex conditions into a deep crisis. Katrina Karkazis offers a nuanced, compassionate picture of these charged issues in Fixing Sex, the first book to examine contemporary controversies over the medical management of intersexuality in the United States from the multiple perspectives of those most intimately involved.Drawing extensively on interviews with adults with intersex conditions, parents, and physicians, Karkazis moves beyond the heated rhetoric to reveal the complex reality of how intersexuality is understood, treated, and experienced today. As she unravels the historical, technological, social, and political forces that have culminated in debates surrounding intersexuality, Karkazis exposes the contentious disagreements among theorists, physicians, intersex adults, activists, and parents--and all that those debates imply about gender and the changing landscape of intersex management. She argues that by viewing intersexuality exclusively through a narrow medical lens we avoid much more difficult questions. Do gender atypical bodies require treatment? Should physicians intervene to control the "sex" of the body? As this illuminating book reveals, debates over treatment for intersexuality force reassessment of the seemingly natural connections between gender, biology, and the body.