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#1 NATIONAL BESTSELLER A shocking exposé of the deadliest killing spree in Canadian history, and how police tragically failed its…
victims and survivors.As news broke of a killer rampaging across the tiny community of Portapique, Nova Scotia, late on April 18, 2020, details were oddly hard to come by. Who was the killer? Why was he not apprehended? What were police doing? How many were dead? And why was the gunman still on the loose the next morning and killing again? The RCMP was largely silent then, and continued to obscure the actions of denturist Gabriel Wortman after an officer shot and killed him at a gas station during a chance encounter. Though retired as an investigative journalist and author, Paul Palango spent much of his career reporting on Canada’s troubled national police force. Watching the RCMP stumble through the Portapique massacre, only a few hours from his Nova Scotia home, Palango knew the story behind the headlines was more complicated and damning than anyone was willing to admit. With the COVID-19 lockdown sealing off the Maritimes, no journalist in the province knew the RCMP better than Palango did. Within a month, he was back in print and on the radio, peeling away the layers of this murderous episode as only he could, and unearthing the collision of failure and malfeasance that cost a quiet community 22 innocent lives.Howard County Law Enforcement (Images of America)
By Tom Kelley, Jon Zeck. 2014
Since the 1880s, when a Howard County sheriff's deputy shot the mayor of Kokomo during the commission of a burglary,…
Howard County law enforcement officers have played an important role in the community's history. Police officers, deputies, and troopers cleared rowdies out of the junction neighborhood, walked downtown beats, rescued tornado survivors, quelled civil disturbances, cleaned up tragic accidents, and solved grisly murders. By the mid-1940s, a new generation of war veterans came home with a spirit of progress and experience in leadership. The foundation of compassion, perseverance, and integrity they established in Howard County law enforcement has defined their unswerving commitment to the safety of the community and to one another. Images of America: Howard County Law Enforcement tells their story.Women in Blue
By Cheryl Mullenbach. 2016
They were called sleuths in skirts, guardian mothers, copettes, and police in petticoats. It would be a long time—well over…
150 years—before women in law enforcement were known simply as police officers. Balancing the stories of trailblazers from the past with those of today’s dedicated officers, chiefs, FBI agents, and forensics experts, this collection of riveting biographies traces the evolution of women in policing. Women in Blue inspires readers to value those who broke through barriers—often enduring ridicule and discrimination as they fought for equality—while original interviews shed light on the daily challenges, rewards, and life on the job of various women currently in the trenches of law enforcement. The chronological progression puts hot-button issues like police brutality, race relations, and the treatment of suspects and prisoners into historic context and shows how many women in law enforcement are working to challenge and improve their field. This rich, authoritative history is packed with colorful anecdotes, excerpts from primary sources, and sidebars on related topics and includes photos, a bibliography, source notes, and a list of organizations interested teens can explore to learn more about the world of law enforcement, making it an indispensable resource for aspiring sleuths, officers, agents, crime scene investigators, and more.Treatment of Thyroid Tumor
By Hitoshi Noguchi, Takahiro Okamoto, Yasuhiro Ito, Hiroshi Takami, Akira Yoshida. 2012
Creating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and…
then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have established positions in clinical practice in North America and in Western European countries. In Japan, however, where radioisotope facilities are of limited availability, treatment plans for differentiated thyroid cancer differ considerably from those of America and Europe, and the associated clinical guidelines need modification before they can be adopted. In addition, although thyroid tumor is a common disease in endocrine practice, its management can differ even among specialists. Thus, a Japanese clinical guideline for the treatment of thyroid tumor was desired by many clinicians. As a combination of evidence-based and consensus-based guidelines for the treatment of thyroid tumor, this book offers alternatives to conventional approaches in the West. Ultimately, the authors hope the guideline will lead to the best possible treatment for patients all over the world in the not-distant future.Everything You Need to Know to Manage Type 2 Diabetes: Simple Steps for Surviving and Thriving with the Low GI Plan
By Kaye Foster-Powell, Jennie Brand-Miller, Stephen Colagiuri, Alan Barclay. 2007
A practical, easy-to-use guide to help you manage type 2 diabetes or prediabetes If you are one of the millions…
of people living with diabetes or prediabetes, you may feel like you're inundated with information on how to manage your condition. The good news is that we now know a lot more about managing diabetes or reducing your risk of developing it--and here, the world's foremost glycemic index experts share their wisdom. Rather than blind you with science or swamp you with facts, Everything You Need to Know to Manage Type 2 Diabetes sets out clearly and simply what you need to eat and do to help you: Reduce your risk of developing diabetes Improve your insulin sensitivity and your cardiovascular health Keep your blood glucose levels, blood pressure, and blood fats under control Reduce your body fat and maintain a healthy body With tips and strategies for working with your doctor, the most recent info on medications, and guidance on the best foods to eat (at home or at a restaurant), Everything You Need to Know to Manage Type 2 Diabetes offers uncomplicated, straightforward advice to help you survive--and thrive.Low GI Diet: Managing Type 2 Diabetes
By Kaye Foster-Powell, Jennie Brand-Miller. 2014
The revised edition of the essential handbook on how to reduce the health risks posed by Type 2 Diabetes -…
from the team behind the internationally bestselling Low GI series. Are you living with type 2 diabetes or pre-diabetes and trying to manage your condition? In Australia and New Zealand alone diabetes and pre-diabetes affect 1 in 4 people. Every day nearly 300 people, including children, develop type 2 diabetes and for every person diagnosed with diabetes there's someone else with undiagnosed diabetes. The good news is that we now know a lot more about managing diabetes or reducing your risk of developing it. Low GI Diet: Managing Type 2 Diabetes cuts through the confusion of conflicting advice and sets out clearly and simply what you need to eat and do to help you: reduce your risk of developing diabetes; improve your cardiovascular health; keep your blood glucose levels, blood pressure and blood fats under control; and maintain a healthy body. This book is a practical guide to help you manage your diabetes or pre-diabetes with diet and lifestyle from the highly qualified, specialist team of authors led by world Low GI authority Professor Jennie Brand-Miller. It shows what you can do for yourself - and why. Best of all, this information is good advice for everyone in your family, not just you.Diabetes and Cardiovascular Disease
By Francesco Paneni, Francesco Cosentino. 2015
This book provides a practical hands-on approach to the management of patients with diabetes and cardiovascular disease, with original and…
up-to-date coverage of a variety of aspects of emerging clinical importance. Practical advice is offered on diagnosis, risk stratification, management of cardiovascular risk factors and available drug therapies. Appropriate myocardial revascularization strategies are explained and the current state of knowledge is documented regarding target-led multifactorial treatment and the management of acute coronary syndromes, heart failure, and cerebrovascular disease. New algorithms for diagnosis and treatment are presented and to ensure ease of reference each chapter includes a box with practical recommendations as well as informative color illustrations and tables. The handbook will be of value for all cardiologists and diabetologists and will be especially helpful for young cardiologists, who are ever more frequently confronted by patients with diabetes and cardiovascular disease.Genetic Damage in Human Spermatozoa
By Monica Muratori, Elisabetta Baldi. 2014
There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate…
during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.Thymic Development and Selection of T Lymphocytes
By Thomas Boehm, Yousuke Takahama. 2014
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place.…
Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.Obesity and Breast Cancer
By Kristy A. Brown, Evan R. Simpson. 2014
Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been…
shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are oestrogen-dependent. Since the ovaries no longer produce oestrogens after menopause, and that circulating levels are negligible, it is evident that it is the oestrogens produced locally within the breast adipose that are responsible for the increased growth of breast cancer cells. Aromatase is the enzyme that converts androgens into oestrogens and its regulation is dependent on the activity of a number of tissue-specific promoters. Targeting oestrogen biosynthesis in obesity may be useful for the prevention of breast cancer. Aromatase inhibitors are efficacious at treating postmenopausal breast cancer and recent studies suggest that they may also be useful in the prevention setting. However, these compounds inhibit the catalytic activity of aromatase and as a consequence lead to a number of undesirable side-effects, including arthralgia and possible cognitive defects due to inhibition of aromatase in the bone and brain, respectively. Novel therapies, such as those employed to treat obesity-associated disease, including anti-diabetics, may prove successful at inhibiting aromatase specifically within the breast. This SpringerBrief will explore all of these issues in depth and the authors are in a unique position to write about this topic, having extensive experience in the field of aromatase research.The Cleveland Clinic Manual of Dynamic Endocrine Testing
By Ahmet Bahadir Ergin, A. Laurence Kennedy, Manjula K. Gupta, Amir H. Hamrahian. 2015
Developed via a peer review process that included 25 experienced endocrinologists and utilizing the best current evidence, The Cleveland Clinic…
has created a practical set of protocols for over 25 commonly used dynamic endocrine tests. The cornerstone of clinical endocrinology, these evidence-based protocols play an important role in clinical decision-making and are important element of billing and compliance with high quality standards. Included here are various tests for pituitary and adrenal disorders, thyroid disorders, and glucose metabolism and pancreatic disorders, presented systematically with indications, preparation, materials needed, precautions, procedure, interpretation, and caveats. Filling the gap left by a lack of national guidelines, The Cleveland Clinic Manual of Dynamic Endocrine Testing is an up-to-date practical guide for endocrinologists, nurses, and their staff, inside or outside of the US, who need to perform and interpret dynamic endocrine testing in their everyday practice, as well as medical students, residents and fellows who have interest in endocrinology.Stem Cell Therapy in Lysosomal Storage Diseases
By Jaap Jan Boelens, Robert Wynn. 2013
Stem Cell therapy for lysosomal diseases (LSDs) is developing rapidly. This volume discusses the history, current practice and future perspectives…
of stem cells in inborn errors of metabolism (IEM) and provides an international perspective on progress, limitations, and future directions (e. g. gene therapy, iPS, ES) in the field. Beginning with an overview of these diseases, the book covers the breadth of this topic from treatment options, bone marrow transplantation, and alternative treatment options, through long-term outcomes and future perspectives.Therapeutic Perspectives in Type-1 Diabetes
By Prachi Singh, Ganesh R Kokil, Karnaker R Tupally, Kingshuk Poddar, Aaron Tan, Venky Venkatesan, Harendra S. Parekh, Giorgia Pastorin. 2016
This book provides critical insights into and appraisals ofrecent breakthroughs in type 1 diabetes modulation, with a particular emphasison the…
potential impact of current prevention and treatment strategies. It alsodiscusses recent successes and failures in clinical trials. Presenting ancomprehensive overview of the disease, it is especially useful for newcomers inthe field. It also includes illustrations, which make it easy for the reader tograsp the basic concepts involved. Furthermore, the tables include concise andeasy-to-understand information on current clinical trials.Diabetes Management in Clinical Practice
By Tahseen A. Chowdhury. 2014
At a time when clinicians are bombarded with masses of clinical information from numerous sources, and the wide variety of…
changes/advances in diabetes management, there is a need for a concise, easy-to-read book that provides an up-to-date review of the major advances in management of diabetes, with an evidence-based approach. This book is a collection of short chapters, each focused on a subject related to the management of diabetes and its complications. The chapters are written by acknowledged experts in the field, who are also clinicians dealing with diabetes on a day-to-day basis. The text is highly evidence based and well referenced with reviews of relevant trials. It includes the latest developments in diabetes management, prospects for future therapies and avenues of research, as well as therapies currently undergoing clinical trial. In order to facilitate ease of reading, it has a user-friendly appearance, with multiple headings, illustrations and summary boxes. The primary audience is clinical, including all healthcare professionals involved in the management of diabetes and its complications. This encompasses diabetologists and endocrinologists, family practitioners with an interest in diabetes, specialist nurses, dietitians and podiatrists.Labor Unions, Management Innovation and Organizational Change in Police Departments
By John Decarlo, Michael J. Jenkins. 2015
This Brief examines the role of Police Unions in law enforcement policy development. It provides an overview of the historical…
and political background of police labor unions, and takes a critical look at the shifting perception of labor unions from generally positive to somewhat negative, to compare this perception with their real impact. It examines the perceived role that unions play, whether positive, negative, or neutral in the development and advancement of contemporary law enforcement agencies and their respective policies. This work provides a multisite survey of police administrators' views and opinions on police union impact on a variety of police functions including: delivery of services, prevention of crime and disorder, and interaction with the public. The results of this research provide a comprehensive look at ways to improve the ways police departments operate and how they improve and enhance legitimacy in their communities. It provides a context for the current state of the public sector labor relations environment. It will be of interest to researchers in criminology and criminal justice, police science, and public policy.Glycemic Control in the Hospitalized Patient
By Lillian F. Lien, Leonor Corsino, Mark N. Feinglos, Mary E. Cox. 2011
Glycemic Control in the Hospitalized Patient: A Comprehensive Clinical Guide is a unique, practical resource for health care providers dealing…
with hyperglycemia in the inpatient setting. Outlining a hands-on approach used by the Duke University Inpatient Diabetes Management team, the book discusses a wide range of scenarios that occur while treating patients with hyperglycemia, including challenging circumstances such as steroids and tube feeding regimens. Special emphasis is given to insulin therapy. The chapters are written by a group of health care providers with extensive, pioneering experience in hyperglycemia control in the inpatient setting at the Duke University Medical Center. The book includes the most up-to-date scientific evidence and information and is addressed to not only hospitalists and general internists but also endocrinology fellows, residents, nurse practitioners, nurses, and other primary care practitioners who treat patients in the inpatient setting. The focus is clearly on practical, patient-care topics. Glycemic Control in the Hospitalized Patient: A Comprehensive Clinical Guide is a first-of-its kind, comprehensive guide to state-of-the-art inpatient glycemic management.Hormones, Intrauterine Health and Programming
By Jonathan R Seckl, Yves Christen. 2014
The authors address in particular the role of hormones and their links with other maternal environmental mediators in developmental programming.…
The crucial nature of the placenta as an interface and target between maternal and foetal environments is addressed. Emphasis is made on the emerging science of epigenetics as a potential explanation for how environmental events that occur during brief windows of development may exert effects that impact upon somatic cells through many rounds of mitosis for much of the life span of the subsequent organism.International Assistance to Police Reform
By Steffen Eckhard. 2016
This book comparespolice reform operations in Kosovo and Afghanistan, addressing the internalmachinery that makes peace operations work--or not. Recognizing that…
the chancesfor effective peacebuilding vary widely across contexts, this book investigatesthe impact of one of the few variables that peacebuilders do control: themanagement and design of peace operations. Building on fieldresearch and over one hundred expert interviews, Internationalassistance to police reform: Managing Peacebuilding systematically compares such operations in twodifferent contexts--Kosovo and Afghanistan--by focusing specifically oninternational assistance for local police reform since 1999. Four comprehensivecase studies examine operations in Kosovo and Afghanistan before and after theEuropean Union took over police reform responsibilities: in Kosovo from the Organization for Security and Co-operationin Europe (OSCE) and in Afghanistan from the German government. Speaking toscholars and practitioners in domestic and international organizations, the bookdrills in the complex relation between headquarter diplomats and field levelconflict experts. Its findings combine to a set of recommendations forpolicy-makers to better align their operations to the contentious politics ofconflict management and peacebuilding.Managing Diabetic Nephropathies in Clinical Practice
By George L. L. Bakris, Allison Hahr, Romesh Khardori, Daisuke Koya, Mark Molitch, Friedrich C. C. Prischl, Guntram Schernthaner, Bijin Thajudeen. 2017
An overview of the diagnosis, treatment, and long-term management of diabetic-related kidney disease in clinical practice. Includes an evidence-based discussion…
of currently available and experimental drug therapies currently in development, guided by international consensus guidelines. Ideal for physicians, medical trainees, nurses and other medical professional that regularly screen and treat patients with all types of diabetes.Police Pursuit Driving
By Cynthia Lum, Geoffrey P. Alpert. 2014
Police pursuits, often receiving a lot of media attention, have become a topic of concern and priority for both law…
enforcement and the communities they serve They often come with high risks for the well-being of community members and for both the police officers involved in the chase as well as for the fleeing suspects In this brief, we summarize what is known about police pursuits, from both legal decisions and criminological research. We then discuss the impact of this research on police pursuit policy, court decisions, and media reports. We offer suggestions about the need for more development and use of research, and the challenges for research to be integrated into police policies, training, supervision and accountability systems.