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Single-Minded: My Life in Business
By Claude Littner. 2016
The story of a high-stakes careerClaude Littner is best known as the mercilessly tough interviewer on the BBC's award-winning The…
Apprentice. His abrupt style and zero-tolerance policy on nonsense have become the highlights of every series. But what is he like in real business?SINGLE-MINDED reveals the story of Claude's varied career and the turbulent years that shaped him. From being told at school he would never amount to anything to his current status as a boardroom heavyweight both on-screen and off it, success has never come easy. Claude's complex, fascinating work has taken him into many different industries and countries, encompassing:- retail start-ups- knife-edge company rescue missions- the bruising rough-and-tumble of Premier League football- facing down French trade unions- taking on Texan oil barons in multi-million-dollar deals- and, in the private sphere, conquering life-threatening illnessAs Lord Sugar writes in the foreword to Claude's story, the book 'should be recommended reading for anyone who aspires to make their way in business . . . It is instructive and entertaining, providing an interesting insight into the ups and downs of business life and how single-mindedness, openness and determination can yield dividends both financial and personal.'The Shard: The Vision of Irvine Sellar
By Howard Watson. 2017
'We were told we would never get planning consent and we did. We were told we would never be able…
to fund it and we did. Then we were told we would never be able to build it and we did.' Irvine SellarIn 2000, Irvine Sellar, a former market trader famous for helping to create the look of the Swinging Sixties on Carnaby Street, stood on a rooftop in Southwark, London, and decided to build the tallest building in western Europe. He had virtually no experience, and he wanted to build at the wrong height, in the wrong place, on the wrong side of the river and at the wrong time.Twelve years later, the Shard, a 'vertical city' designed by one of the world's leading architects, Renzo Piano, changed the skyline of London. It immediately became one of the most instantly recognizable and admired contemporary buildings in the world.This is the story of one man's vision for London and his determination to redefine an ancient but maligned part of the city despite seemingly insurmountable challenges including mass opposition, a huge planning inquiry, the financial crash, and major construction issues that required radical improvisation at every turn. At every twist in the tale, Sellar refused to give up.The Shard is a tale of extreme ambition, innovation and a relentless desire to recast the skyscraper as a force for good.Wheelchair Warrior: Gangs, Disability, and Basketball
By Melvin Juette, Ronald Berger. 2008
What's that pig outdoors?
By Henry Kisor. 2010
Henry Kisor lost his hearing at age three to meningitis and encephalitis but went on to excel in the most…
verbal of professions as a literary journalist. This new and expanded edition of Kisor's engrossing memoir recounts his life as a deaf person in a hearing world and addresses heartening changes over the last two decades due to the Americans with Disabilities Act of 1990 and advancements in cochlear implants and modes of communication. _x000B_Kisor tells of his parents' drive to raise him as a member of the hearing and speaking world by teaching him effective lip-reading skills at a young age and encouraging him to communicate with his hearing peers. _x000B_Kisor updates the continuing disagreements between those who advocate sign language and those who practice speech and lip-reading, discusses the increased acceptance of deaf people's abilities and idiosyncrasies, and considers technological advancements that have enabled deaf people to communicate with the hearing world on its own terms.Dark Genius of Wall Street: The Misunderstood Life of Jay Gould, King of the Robber Barons
By Edward J. Renehan Jr.. 2005
Though reviled for more than a century as Wall Street's greatest villain, Jay Gould was in fact its most original…
creative genius. Gould was the robber baron's robber baron, the most astute financial and business strategist of his time and also the most widely hated. In Dark Genius of Wall Street, acclaimed biographer Edward J. Renehan, Jr. , combines lively anecdotes with the rich social tapestry of the Gilded Age to paint the portrait of the most talented financial buccaneer of his generation-- and one of the inventors of modern business.Preston Tucker and His Battle to Build the Car of Tomorrow
By Jay Leno, Steve Lehto. 2016
In the wake of World War II, the U.S. automobile industry was fully unprepared to meet the growing demands of…
the public, for whom they had not made any cars for years. In stepped Preston Tucker, a salesman extraordinaire who announced the building of a revolutionary new car: the Tucker '48, the first car in almost a decade to be built fresh from the ground up. Tucker's car, which would include ingenious advances in design and engineering that other car companies could not match, captured the interest of the public, and automakers in Detroit took notice. Here, author Steve Lehto tackles Tucker's amazing story, relying on a huge trove of documents that has been used by no other writer to date. It is the first comprehensive, authoritative account of Tucker's magnificent car and his battles with the government. And in this book, Lehto finally answers the question automobile aficionados have wondered about for decades: exactly how and why the production of such an innovative car was killed.Building Atlanta: How I Broke Through Segregation to Launch a Business Empire
By Herman Russell, Bob Andelman, Andrew Young. 2014
Born into a blue-collar family in the Jim Crow South, Herman J. Russell built a shoeshine business when he was…
12 years old--and used the profits to buy a vacant lot where he built a duplex while he was still a teen. In the ensuing 50 years, Russell has continued to build and develop businesses, amassing one of the most influential and profitable minority-owned business conglomerates. In Building Atlanta, he shares his inspiring life story, revealing how he overcame racism, poverty, and a debilitating speech impediment to become one of the most successful African American entrepreneurs, Atlanta civic leaders, and unsung heroes of the civil rights movement. Not just a typical rags-to-riches story, Russell achieved his success through focus, planning, and humility and he shares his winning advice throughout. As a millionaire builder before the civil rights movement gained impetus and a friend of Dr. Martin Luther King Jr., Ralph Abernathy, and Andrew Young, he quietly helped finance the civil rights crusade, putting up bond for protestors and providing the funds that kept King's dream alive. Here he provides a wonderful, behind-the-scenes look at the role that the business community--which included black and white individuals working together--played in Atlanta's peaceful progression from the capital of the racially divided Old South to the financial center of the New South.Treatment of Thyroid Tumor
By Hitoshi Noguchi, Takahiro Okamoto, Yasuhiro Ito, Hiroshi Takami, Akira Yoshida. 2012
Creating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and…
then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have established positions in clinical practice in North America and in Western European countries. In Japan, however, where radioisotope facilities are of limited availability, treatment plans for differentiated thyroid cancer differ considerably from those of America and Europe, and the associated clinical guidelines need modification before they can be adopted. In addition, although thyroid tumor is a common disease in endocrine practice, its management can differ even among specialists. Thus, a Japanese clinical guideline for the treatment of thyroid tumor was desired by many clinicians. As a combination of evidence-based and consensus-based guidelines for the treatment of thyroid tumor, this book offers alternatives to conventional approaches in the West. Ultimately, the authors hope the guideline will lead to the best possible treatment for patients all over the world in the not-distant future.Edmund Booth: Deaf Pioneer
By Harry G. Lang. 2004
Edmund Booth was born in 1810 and died in 1905, and during the 94 years of his life, he epitomized…
virtually everything that characterized an American legend of that century. In his prime, Booth stood 6 feet, 3 inches tall, weighed in at 210 pounds, and wore a long, full beard. He taught school in Hartford, CT, then followed his wife-to-be Mary Ann Walworth west to Anamosa, Iowa, where in 1840, he built the area's first frame house. He pulled up stakes nine years later to travel the Overland Trail on his way to join the California Gold Rush. After he returned to Iowa in 1854, he became the editor of the Anamosa Eureka, the local newspaper. Edmund Booth fit perfectly the mold of the ingenious pioneer of 19th-century America, except for one unusual difference -- he was deaf. Edmund Booth: Deaf Pioneer follows the amazing career of this American original and his equally amazing wife in fascinating detail. Author Harry G. Lang vividly portrays Booth and his wife by drawing from a remarkable array of original material. A prolific writer, Booth corresponded with his fiancé from the American School for the Deaf in Hartford, and he kept a journal during his days on the California trail, parts of which have been reproduced here. He also wrote an autobiographical essay when he was 75, and his many newspaper articles through the years bore first-hand witness to the history of his times, from the Civil War to the advent of the 20th century. Edmund Booth depicts a larger-than-life man in larger-than-life times, but perhaps its greatest contribution derives from its narrative about pioneer days as seen through Deaf eyes. Booth became a respected senior statesman of the American Deaf community, and blended with his stories of the era's events are anecdotes and issues vital to Deaf people and their families. His story proves again that extraordinary people vary in many ways, but they often possess a common motive in acting to enhance their own communities.No Map To This Country: One Family's Journey Through Autism
By Jennifer Noonan. 2016
A heartbreaking yet also funny and ultimately empowering memoir revealing the a multi-year journey into the latest science and treatments…
in order to rescue her kids and her family from autism.Everything You Need to Know to Manage Type 2 Diabetes: Simple Steps for Surviving and Thriving with the Low GI Plan
By Kaye Foster-Powell, Jennie Brand-Miller, Stephen Colagiuri, Alan Barclay. 2007
A practical, easy-to-use guide to help you manage type 2 diabetes or prediabetes If you are one of the millions…
of people living with diabetes or prediabetes, you may feel like you're inundated with information on how to manage your condition. The good news is that we now know a lot more about managing diabetes or reducing your risk of developing it--and here, the world's foremost glycemic index experts share their wisdom. Rather than blind you with science or swamp you with facts, Everything You Need to Know to Manage Type 2 Diabetes sets out clearly and simply what you need to eat and do to help you: Reduce your risk of developing diabetes Improve your insulin sensitivity and your cardiovascular health Keep your blood glucose levels, blood pressure, and blood fats under control Reduce your body fat and maintain a healthy body With tips and strategies for working with your doctor, the most recent info on medications, and guidance on the best foods to eat (at home or at a restaurant), Everything You Need to Know to Manage Type 2 Diabetes offers uncomplicated, straightforward advice to help you survive--and thrive.Not All Superheroes Wear Capes
By Quentin Kenihan. 2016
Quentin Kenihan is living proof that superheroes don't need capes, just the right attitude. FOREWORD BY RAY MARTINWhen he was…
a kid, Quentin Kenihan loved Superman. Ironic, really. Quentin didn't need kryptonite to reveal his weakness - born with a rare bone disorder, osteogenesis imperfecta, his bones broke all on their own.When Quentin was seven, Mike Willesee made a documentary about him. Australians fell in love with his wit, and never-say-die attitude. Over the years he grew up before our eyes. But there was a dark side to his life. The true story was never told ... until now. A story of abandonment, drug addiction, dark days and thoughts of suicide. Battling through it all, Quentin's resilience is inspiring.Quentin is now determined to live life the best he can. Just turned 41, he is a filmmaker, stand-up comedian, radio host, actor and film critic; he's hung out with Angelina, accidentally ripped Jennifer Lopez's dress, talked sex with Jean-Claude Van Damme, appeared in MAD MAX and interviewed Julia Gillard, all the while showing that living in a wheelchair doesn't mean staying still.This is an unforgettable, brutally honest, at times heartbreaking memoir. Quentin Kenihan is living proof that superheroes don't need capes, just the right attitude!'Quentin is a hero of mine. Probably the toughest man I have ever met. Read this book and reconsider how hard you think your life is. It is a liberating experience to face life through his eyes.' - RUSSELL CROWELow GI Diet: Managing Type 2 Diabetes
By Kaye Foster-Powell, Jennie Brand-Miller. 2014
The revised edition of the essential handbook on how to reduce the health risks posed by Type 2 Diabetes -…
from the team behind the internationally bestselling Low GI series. Are you living with type 2 diabetes or pre-diabetes and trying to manage your condition? In Australia and New Zealand alone diabetes and pre-diabetes affect 1 in 4 people. Every day nearly 300 people, including children, develop type 2 diabetes and for every person diagnosed with diabetes there's someone else with undiagnosed diabetes. The good news is that we now know a lot more about managing diabetes or reducing your risk of developing it. Low GI Diet: Managing Type 2 Diabetes cuts through the confusion of conflicting advice and sets out clearly and simply what you need to eat and do to help you: reduce your risk of developing diabetes; improve your cardiovascular health; keep your blood glucose levels, blood pressure and blood fats under control; and maintain a healthy body. This book is a practical guide to help you manage your diabetes or pre-diabetes with diet and lifestyle from the highly qualified, specialist team of authors led by world Low GI authority Professor Jennie Brand-Miller. It shows what you can do for yourself - and why. Best of all, this information is good advice for everyone in your family, not just you.Diabetes and Cardiovascular Disease
By Francesco Paneni, Francesco Cosentino. 2015
This book provides a practical hands-on approach to the management of patients with diabetes and cardiovascular disease, with original and…
up-to-date coverage of a variety of aspects of emerging clinical importance. Practical advice is offered on diagnosis, risk stratification, management of cardiovascular risk factors and available drug therapies. Appropriate myocardial revascularization strategies are explained and the current state of knowledge is documented regarding target-led multifactorial treatment and the management of acute coronary syndromes, heart failure, and cerebrovascular disease. New algorithms for diagnosis and treatment are presented and to ensure ease of reference each chapter includes a box with practical recommendations as well as informative color illustrations and tables. The handbook will be of value for all cardiologists and diabetologists and will be especially helpful for young cardiologists, who are ever more frequently confronted by patients with diabetes and cardiovascular disease.Genetic Damage in Human Spermatozoa
By Monica Muratori, Elisabetta Baldi. 2014
There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate…
during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.Thymic Development and Selection of T Lymphocytes
By Thomas Boehm, Yousuke Takahama. 2014
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place.…
Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.Commodore: The Life of Cornelius Vanderbilt
By Edward J. Renehan Jr. 2007
Armed with a trove of previously unreleased archives, Edward J. Renehan Jr. offers a compelling portrait of Cornelius Vanderbilt, who…
built large shipping and rail enterprises into cornerstones of the American economy, and amassed one of the greatest fortunes the world has ever known. This is the definitive biography of a man whose influence on American business was unsurpassed in his day--or any other.Obesity and Breast Cancer
By Kristy A. Brown, Evan R. Simpson. 2014
Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been…
shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are oestrogen-dependent. Since the ovaries no longer produce oestrogens after menopause, and that circulating levels are negligible, it is evident that it is the oestrogens produced locally within the breast adipose that are responsible for the increased growth of breast cancer cells. Aromatase is the enzyme that converts androgens into oestrogens and its regulation is dependent on the activity of a number of tissue-specific promoters. Targeting oestrogen biosynthesis in obesity may be useful for the prevention of breast cancer. Aromatase inhibitors are efficacious at treating postmenopausal breast cancer and recent studies suggest that they may also be useful in the prevention setting. However, these compounds inhibit the catalytic activity of aromatase and as a consequence lead to a number of undesirable side-effects, including arthralgia and possible cognitive defects due to inhibition of aromatase in the bone and brain, respectively. Novel therapies, such as those employed to treat obesity-associated disease, including anti-diabetics, may prove successful at inhibiting aromatase specifically within the breast. This SpringerBrief will explore all of these issues in depth and the authors are in a unique position to write about this topic, having extensive experience in the field of aromatase research.The Cleveland Clinic Manual of Dynamic Endocrine Testing
By Ahmet Bahadir Ergin, A. Laurence Kennedy, Manjula K. Gupta, Amir H. Hamrahian. 2015
Developed via a peer review process that included 25 experienced endocrinologists and utilizing the best current evidence, The Cleveland Clinic…
has created a practical set of protocols for over 25 commonly used dynamic endocrine tests. The cornerstone of clinical endocrinology, these evidence-based protocols play an important role in clinical decision-making and are important element of billing and compliance with high quality standards. Included here are various tests for pituitary and adrenal disorders, thyroid disorders, and glucose metabolism and pancreatic disorders, presented systematically with indications, preparation, materials needed, precautions, procedure, interpretation, and caveats. Filling the gap left by a lack of national guidelines, The Cleveland Clinic Manual of Dynamic Endocrine Testing is an up-to-date practical guide for endocrinologists, nurses, and their staff, inside or outside of the US, who need to perform and interpret dynamic endocrine testing in their everyday practice, as well as medical students, residents and fellows who have interest in endocrinology.Stem Cell Therapy in Lysosomal Storage Diseases
By Jaap Jan Boelens, Robert Wynn. 2013
Stem Cell therapy for lysosomal diseases (LSDs) is developing rapidly. This volume discusses the history, current practice and future perspectives…
of stem cells in inborn errors of metabolism (IEM) and provides an international perspective on progress, limitations, and future directions (e. g. gene therapy, iPS, ES) in the field. Beginning with an overview of these diseases, the book covers the breadth of this topic from treatment options, bone marrow transplantation, and alternative treatment options, through long-term outcomes and future perspectives.