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Wheelchair Warrior: Gangs, Disability, and Basketball
By Melvin Juette, Ronald Berger. 2008
What's that pig outdoors?
By Henry Kisor. 2010
Henry Kisor lost his hearing at age three to meningitis and encephalitis but went on to excel in the most…
verbal of professions as a literary journalist. This new and expanded edition of Kisor's engrossing memoir recounts his life as a deaf person in a hearing world and addresses heartening changes over the last two decades due to the Americans with Disabilities Act of 1990 and advancements in cochlear implants and modes of communication. _x000B_Kisor tells of his parents' drive to raise him as a member of the hearing and speaking world by teaching him effective lip-reading skills at a young age and encouraging him to communicate with his hearing peers. _x000B_Kisor updates the continuing disagreements between those who advocate sign language and those who practice speech and lip-reading, discusses the increased acceptance of deaf people's abilities and idiosyncrasies, and considers technological advancements that have enabled deaf people to communicate with the hearing world on its own terms.Treatment of Thyroid Tumor
By Hitoshi Noguchi, Takahiro Okamoto, Yasuhiro Ito, Hiroshi Takami, Akira Yoshida. 2012
Creating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and…
then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have established positions in clinical practice in North America and in Western European countries. In Japan, however, where radioisotope facilities are of limited availability, treatment plans for differentiated thyroid cancer differ considerably from those of America and Europe, and the associated clinical guidelines need modification before they can be adopted. In addition, although thyroid tumor is a common disease in endocrine practice, its management can differ even among specialists. Thus, a Japanese clinical guideline for the treatment of thyroid tumor was desired by many clinicians. As a combination of evidence-based and consensus-based guidelines for the treatment of thyroid tumor, this book offers alternatives to conventional approaches in the West. Ultimately, the authors hope the guideline will lead to the best possible treatment for patients all over the world in the not-distant future.Edmund Booth: Deaf Pioneer
By Harry G. Lang. 2004
Edmund Booth was born in 1810 and died in 1905, and during the 94 years of his life, he epitomized…
virtually everything that characterized an American legend of that century. In his prime, Booth stood 6 feet, 3 inches tall, weighed in at 210 pounds, and wore a long, full beard. He taught school in Hartford, CT, then followed his wife-to-be Mary Ann Walworth west to Anamosa, Iowa, where in 1840, he built the area's first frame house. He pulled up stakes nine years later to travel the Overland Trail on his way to join the California Gold Rush. After he returned to Iowa in 1854, he became the editor of the Anamosa Eureka, the local newspaper. Edmund Booth fit perfectly the mold of the ingenious pioneer of 19th-century America, except for one unusual difference -- he was deaf. Edmund Booth: Deaf Pioneer follows the amazing career of this American original and his equally amazing wife in fascinating detail. Author Harry G. Lang vividly portrays Booth and his wife by drawing from a remarkable array of original material. A prolific writer, Booth corresponded with his fiancé from the American School for the Deaf in Hartford, and he kept a journal during his days on the California trail, parts of which have been reproduced here. He also wrote an autobiographical essay when he was 75, and his many newspaper articles through the years bore first-hand witness to the history of his times, from the Civil War to the advent of the 20th century. Edmund Booth depicts a larger-than-life man in larger-than-life times, but perhaps its greatest contribution derives from its narrative about pioneer days as seen through Deaf eyes. Booth became a respected senior statesman of the American Deaf community, and blended with his stories of the era's events are anecdotes and issues vital to Deaf people and their families. His story proves again that extraordinary people vary in many ways, but they often possess a common motive in acting to enhance their own communities.No Map To This Country: One Family's Journey Through Autism
By Jennifer Noonan. 2016
A heartbreaking yet also funny and ultimately empowering memoir revealing the a multi-year journey into the latest science and treatments…
in order to rescue her kids and her family from autism.Everything You Need to Know to Manage Type 2 Diabetes: Simple Steps for Surviving and Thriving with the Low GI Plan
By Kaye Foster-Powell, Jennie Brand-Miller, Stephen Colagiuri, Alan Barclay. 2007
A practical, easy-to-use guide to help you manage type 2 diabetes or prediabetes If you are one of the millions…
of people living with diabetes or prediabetes, you may feel like you're inundated with information on how to manage your condition. The good news is that we now know a lot more about managing diabetes or reducing your risk of developing it--and here, the world's foremost glycemic index experts share their wisdom. Rather than blind you with science or swamp you with facts, Everything You Need to Know to Manage Type 2 Diabetes sets out clearly and simply what you need to eat and do to help you: Reduce your risk of developing diabetes Improve your insulin sensitivity and your cardiovascular health Keep your blood glucose levels, blood pressure, and blood fats under control Reduce your body fat and maintain a healthy body With tips and strategies for working with your doctor, the most recent info on medications, and guidance on the best foods to eat (at home or at a restaurant), Everything You Need to Know to Manage Type 2 Diabetes offers uncomplicated, straightforward advice to help you survive--and thrive.Diabetes and Cardiovascular Disease
By Francesco Paneni, Francesco Cosentino. 2015
This book provides a practical hands-on approach to the management of patients with diabetes and cardiovascular disease, with original and…
up-to-date coverage of a variety of aspects of emerging clinical importance. Practical advice is offered on diagnosis, risk stratification, management of cardiovascular risk factors and available drug therapies. Appropriate myocardial revascularization strategies are explained and the current state of knowledge is documented regarding target-led multifactorial treatment and the management of acute coronary syndromes, heart failure, and cerebrovascular disease. New algorithms for diagnosis and treatment are presented and to ensure ease of reference each chapter includes a box with practical recommendations as well as informative color illustrations and tables. The handbook will be of value for all cardiologists and diabetologists and will be especially helpful for young cardiologists, who are ever more frequently confronted by patients with diabetes and cardiovascular disease.Genetic Damage in Human Spermatozoa
By Monica Muratori, Elisabetta Baldi. 2014
There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate…
during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.Thymic Development and Selection of T Lymphocytes
By Thomas Boehm, Yousuke Takahama. 2014
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place.…
Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.Obesity and Breast Cancer
By Kristy A. Brown, Evan R. Simpson. 2014
Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been…
shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are oestrogen-dependent. Since the ovaries no longer produce oestrogens after menopause, and that circulating levels are negligible, it is evident that it is the oestrogens produced locally within the breast adipose that are responsible for the increased growth of breast cancer cells. Aromatase is the enzyme that converts androgens into oestrogens and its regulation is dependent on the activity of a number of tissue-specific promoters. Targeting oestrogen biosynthesis in obesity may be useful for the prevention of breast cancer. Aromatase inhibitors are efficacious at treating postmenopausal breast cancer and recent studies suggest that they may also be useful in the prevention setting. However, these compounds inhibit the catalytic activity of aromatase and as a consequence lead to a number of undesirable side-effects, including arthralgia and possible cognitive defects due to inhibition of aromatase in the bone and brain, respectively. Novel therapies, such as those employed to treat obesity-associated disease, including anti-diabetics, may prove successful at inhibiting aromatase specifically within the breast. This SpringerBrief will explore all of these issues in depth and the authors are in a unique position to write about this topic, having extensive experience in the field of aromatase research.The Cleveland Clinic Manual of Dynamic Endocrine Testing
By Ahmet Bahadir Ergin, A. Laurence Kennedy, Manjula K. Gupta, Amir H. Hamrahian. 2015
Developed via a peer review process that included 25 experienced endocrinologists and utilizing the best current evidence, The Cleveland Clinic…
has created a practical set of protocols for over 25 commonly used dynamic endocrine tests. The cornerstone of clinical endocrinology, these evidence-based protocols play an important role in clinical decision-making and are important element of billing and compliance with high quality standards. Included here are various tests for pituitary and adrenal disorders, thyroid disorders, and glucose metabolism and pancreatic disorders, presented systematically with indications, preparation, materials needed, precautions, procedure, interpretation, and caveats. Filling the gap left by a lack of national guidelines, The Cleveland Clinic Manual of Dynamic Endocrine Testing is an up-to-date practical guide for endocrinologists, nurses, and their staff, inside or outside of the US, who need to perform and interpret dynamic endocrine testing in their everyday practice, as well as medical students, residents and fellows who have interest in endocrinology.Stem Cell Therapy in Lysosomal Storage Diseases
By Jaap Jan Boelens, Robert Wynn. 2013
Stem Cell therapy for lysosomal diseases (LSDs) is developing rapidly. This volume discusses the history, current practice and future perspectives…
of stem cells in inborn errors of metabolism (IEM) and provides an international perspective on progress, limitations, and future directions (e. g. gene therapy, iPS, ES) in the field. Beginning with an overview of these diseases, the book covers the breadth of this topic from treatment options, bone marrow transplantation, and alternative treatment options, through long-term outcomes and future perspectives.Therapeutic Perspectives in Type-1 Diabetes
By Prachi Singh, Ganesh R Kokil, Karnaker R Tupally, Kingshuk Poddar, Aaron Tan, Venky Venkatesan, Harendra S. Parekh, Giorgia Pastorin. 2016
This book provides critical insights into and appraisals ofrecent breakthroughs in type 1 diabetes modulation, with a particular emphasison the…
potential impact of current prevention and treatment strategies. It alsodiscusses recent successes and failures in clinical trials. Presenting ancomprehensive overview of the disease, it is especially useful for newcomers inthe field. It also includes illustrations, which make it easy for the reader tograsp the basic concepts involved. Furthermore, the tables include concise andeasy-to-understand information on current clinical trials.Diabetes Management in Clinical Practice
By Tahseen A. Chowdhury. 2014
At a time when clinicians are bombarded with masses of clinical information from numerous sources, and the wide variety of…
changes/advances in diabetes management, there is a need for a concise, easy-to-read book that provides an up-to-date review of the major advances in management of diabetes, with an evidence-based approach. This book is a collection of short chapters, each focused on a subject related to the management of diabetes and its complications. The chapters are written by acknowledged experts in the field, who are also clinicians dealing with diabetes on a day-to-day basis. The text is highly evidence based and well referenced with reviews of relevant trials. It includes the latest developments in diabetes management, prospects for future therapies and avenues of research, as well as therapies currently undergoing clinical trial. In order to facilitate ease of reading, it has a user-friendly appearance, with multiple headings, illustrations and summary boxes. The primary audience is clinical, including all healthcare professionals involved in the management of diabetes and its complications. This encompasses diabetologists and endocrinologists, family practitioners with an interest in diabetes, specialist nurses, dietitians and podiatrists.Glycemic Control in the Hospitalized Patient
By Lillian F. Lien, Leonor Corsino, Mark N. Feinglos, Mary E. Cox. 2011
Glycemic Control in the Hospitalized Patient: A Comprehensive Clinical Guide is a unique, practical resource for health care providers dealing…
with hyperglycemia in the inpatient setting. Outlining a hands-on approach used by the Duke University Inpatient Diabetes Management team, the book discusses a wide range of scenarios that occur while treating patients with hyperglycemia, including challenging circumstances such as steroids and tube feeding regimens. Special emphasis is given to insulin therapy. The chapters are written by a group of health care providers with extensive, pioneering experience in hyperglycemia control in the inpatient setting at the Duke University Medical Center. The book includes the most up-to-date scientific evidence and information and is addressed to not only hospitalists and general internists but also endocrinology fellows, residents, nurse practitioners, nurses, and other primary care practitioners who treat patients in the inpatient setting. The focus is clearly on practical, patient-care topics. Glycemic Control in the Hospitalized Patient: A Comprehensive Clinical Guide is a first-of-its kind, comprehensive guide to state-of-the-art inpatient glycemic management.Hormones, Intrauterine Health and Programming
By Jonathan R Seckl, Yves Christen. 2014
The authors address in particular the role of hormones and their links with other maternal environmental mediators in developmental programming.…
The crucial nature of the placenta as an interface and target between maternal and foetal environments is addressed. Emphasis is made on the emerging science of epigenetics as a potential explanation for how environmental events that occur during brief windows of development may exert effects that impact upon somatic cells through many rounds of mitosis for much of the life span of the subsequent organism.Managing Diabetic Nephropathies in Clinical Practice
By George L. L. Bakris, Allison Hahr, Romesh Khardori, Daisuke Koya, Mark Molitch, Friedrich C. C. Prischl, Guntram Schernthaner, Bijin Thajudeen. 2017
An overview of the diagnosis, treatment, and long-term management of diabetic-related kidney disease in clinical practice. Includes an evidence-based discussion…
of currently available and experimental drug therapies currently in development, guided by international consensus guidelines. Ideal for physicians, medical trainees, nurses and other medical professional that regularly screen and treat patients with all types of diabetes.The Complete Diabetes Organizer
By Leslie Josel, Susan Weiner. 2013
Is your lack of organization impacting your ability to effectively manage your diabetes? Do you run out of supplies and…
forget endocrinologist appointments? Do you find snacks in your pantry that expired sometime before the insulin pump was invented? Do you struggle to keep track of health-care invoices and payments? Do you succeed at keeping an active health journal for a week or two and then neglect it for a year or two?It sounds like you could use The Complete Diabetes Organizer!Within the pages of this book, diabetes educator Susan Weiner and organizing guru Leslie Josel provide you with dependable strategies and ideas designed to help streamline your diabetes care and simplify your life. From her distinguished career and experience in the fields of diabetes and dietetics, Susan Weiner brings helpful tips and tricks that are guaranteed to ease daily mechanics, promote improved nutrition, and relieve stress caused by disorder and confusion. Certified professional organizer and ADHD Specialist Leslie Josel applies her expertise to the topic of diabetes, with simple, surefire techniques that will allow you to disentangle yourself from the clutches of chronic disorganization.The Complete Diabetes Organizer is your guidebook to maintaining your diabetes with less effort and more confidence, allowing you to focus on enjoying a healthier, stress-free life.Freedom from Fred: Living with Friedreich's Ataxia
By Anna Magdalene Handley. 2014
On the night of a debutante ball, events set in motion an emotive and intimate portrayal of the revelation of…
a life changing condition. Anna Magdalene plunges deep into a personal maelstrom that is both tender and hard-hitting as it explores the hidden recesses of social understanding of her condition, Friedreich's Ataxia. On the quest for healing, Anna embarks on brave and sometimes strange journeys of enlightenment to free herself from the bonds of her condition. In one of these adventures she stumbles on an unexpected answer that brings a true light in the most disarming way, changing her whole view of what freedom is. Simultaneously, she discovers a mutual hope to join life again and a way to live with her condition, 'Fred', while she must. (Blurb by Anna's Carers, Pierre and Lee Figueira)Drosophila Models for Human Diseases (Advances in Experimental Medicine and Biology #1076)
By Masamitsu Yamaguchi. 2018
Most biological pathways physical and neurological properties are highly conserved between humans and Drosophila and nearly 75 of…
human disease-causing genes have a functional homologue in Drosophila This volume provides recent advances in Drosophila models for various human diseases with each chapter providing a review of studies involving Drosophila models as well as detailed protocols commonly used in laboratories Starting with a review of Drosophila s value as a highly tractable model organism for studying human diseases subsequent chapters present Drosophila models for specific human diseases The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases