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Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications
By Naranjan S. Dhalla, R. C. Sobti, Masatoshi Watanabe, Aastha Sobti. 2021
This book discusses the organ-specific systemic manifestations of COVID-19. The initial chapters of the book review the origin and evolution…
of the coronaviruses, followed by pathogenesis and immune response during COVID-19 infection. The book also provides insight into the role of angiotensin-converting enzyme 2 in the onset of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis. It summarizes the neurological aspects of SARS-CoV2, including transmission pathways, mechanisms of invasion into the nervous system, and mechanisms of neurological disease. It also delineates the association of severe disease with high blood plasma levels of inflammatory cytokines and inflammatory markers in SARS-CoV-2 infection. Lastly, it discusses the perturbation of gut microbiota by SARS-CoV-2 and uncovers the potential risk of virus infection on reproductive health.Sonomyography: Dynamic and Functional Assessment of Muscle Using Ultrasound Imaging (Series in BioEngineering)
By Yong-Ping Zheng, Yongjin Zhou. 2021
This book explains the exciting field of sonomyography (SMG), which makes it possible to use continuous signals detected by ultrasound…
images in real time to evaluate muscle functions. After an introduction, the book discusses the methods to extract and analyse different SMG signals, including muscle thickness, penetration angle, fascicle length, contraction activity, and muscle cross-sectional areas, etc. It then describes the mono-modal applications of sonomyography: posture recognition, prosthesis control, muscle training, muscle strength (fall risk assessment), fatigue assessment, and the assessment of dysfunctional muscles. The book also shows how to combine sonomyography with additional muscle assessment methods, in particular EMG, MMG, and motion sensors. Lastly, it provides an overview of the potential applications in sport science, rehabilitation, fitness, and elderly health.Health Care Information Systems: A Practical Approach for Health Care Management
By John P. Glaser, Karen A. Wager, Frances W. Lee. 2022
The most up-to-date edition of the gold standard in health care information system references In the newly revised Fifth Edition…
of Health Care Information Systems, veteran healthcare information management experts and educators Karen A. Wager and Frances Wickham Lee, along with nationally-recognized leader in health information technology, John P. Glaser, deliver a one-stop resource for graduate and upper-level undergraduate students to gain the knowledge and develop the skills they need to manage information and information systems technology in the new healthcare environment. The latest edition sees its focus shift from the adoption of health care information systems and electronic health records to making effective use of health care data, information, and systems and optimizing their impact. New additions to this celebrated text include: Explorations of how health care information systems and information technology can be used to support national quality initiatives, value-based payment, population health management, and precision health and quality reporting Discussions of how issues like interoperability, electronic health record usability, and health IT safety are being (or not being) addressed Treatments of the roles played by data governance and analytics in clinical decision making and healthcare operations. Filled with case studies, supplemental resources, and engaging examinations of critical areas in health care information system use, management, implementation, and support, Health Care Information Systems is an ideal reference for students taking courses in business administration, public health, health administration, medicine, health informatics and health care management.New Drug Development for Known and Emerging Viruses (Methods & Principles in Medicinal Chemistry)
By Raimund Mannhold, Jörg Holenz. 2022
Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy…
of the past decades Written by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic. New Drug Development for Known and Emerging Viruses describes the discovery and development process for antiviral agents for different classes of viruses and targets based on the experiences from the nine human viruses for which approved drugs are on the market (HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV, and VZV). It covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and looks at novel antiviral strategies against emerging viruses. Covers the entire field of antiviral drug discovery and development Addresses the need for antiviral drugs to combat major health threats such as Ebola, Zika, West Nile, and SARS Coronavirus-2 Summarizes the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, both from the medicinal chemistry and the pharmacological angle Discusses practical and strategic challenges in the drug discovery and development process, including screening technologies, latency, and toxicity issues New Developments in Antiviral Drugs is an important book for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists, and will be of great interest to those in the pharmaceutical industry and public health agencies.Dental Neuroimaging: The Role of the Brain in Oral Functions
By Chia-Shu Lin. 2022
DENTAL NEUROIMAGING Provides the latest neuroimaging-based evidence on the brain mechanisms of oral functions Dental Neuroimaging: The Role of the…
Brain in Oral Functions provides an up-to-date overview of neuroimaging research on the neural mechanisms underlying mastication, swallowing, sensory processing, and other oral topics. Divided into three parts, the book first introduces the theoretical framework of the brain-stomatognathic axis, clinical assessments for oral function, and neuroimaging methods. The second part presents recent neuroimaging findings of oral sensory and motor functions such as somatosensation, gustation, and orofacial pain and anxiety. The book concludes with a review of recent translational research and discussion of the application of neuroimaging in clinical management. Throughout the text, boxed sections highlight key information about cognitive neuroscience, imaging techniques, interpreting neuroimaging results, and relating research findings to clinical practice. Covers specific clinical applications of dental neuroimaging in geriatric dentistry and in brain plasticity and adaptation Summarizes classic research works in neuroscience and oral science Discusses potential clinical applications of neuroimaging in dental practice Features chapter summaries, further reading links, guided clinical scenarios, and numerous figures and tables Offering a systematic introduction to brain science and how it relates to dental medicine, Dental Neuroimaging: The Role of the Brain in Oral Functions is essential reading for students and researchers in disciplines such as neuroscience, neuroanatomy, oral physiology, dentistry and oral healthcare, speech therapy, and oral rehabilitation.Fundamentals of Pharmacology for Children's Nurses (Fundamentals)
By Ian Peate, Peter Dryden. 2022
Registered Nurses must have thorough knowledge of pharmacology, medicines administration, and the effects of medicines. Fundamentals of Pharmacology for Children's Nurses is written for nurses…
and allied health professionals involved in the care of children and young people (CYP) to focus exclusively on pharmacology. Filling a gap in current literature on the subject, this much-needed resource develops the competence and confidence required to prescribe, dispense, and administer medicines to children and young people. Emphasising the importance of patient-centered care to CYP, the text describes the role of the healthcare provider working with CYP and their families; explains how to use pharmaceutical and prescribing reference guides; discusses legal and ethical issues; examines pharmacodynamics and pharmacokinetics, and more. Helping readers respond appropriately and compassionately to the needs of those receiving care and their families, this textbook: Covers a wide range of medications used in diabetes, cancer, mental health, and other areas Features a wealth of full-colour images and numerous pedagogical tools including learning objectives, self-test questions, and reflective exercises to enable readers to contextualise and assess their knowledge Presents case studies to reinforce learning, and illustrate the application of theory to practice Provides authoritative and practical guidance on formulations, adverse drug reactions, analgesics, antibiotics, immunisations, and the medications most commonly used when providing care to CYP Includes access to a companion website with interactive MCQs, case studies, references, an image bank, and links to further reading and supplemental resources Fundamentals of Pharmacology for Children's Nurses is essential reading for undergraduate children’s nursing students, trainee nursing associates, those undertaking healthcare programmes of study, as well as those seeking to better understand pharmacology.This book helps to recognize the rights of refugees and provides a framework to identify and approach health needs, from…
basic elements like service mapping and initial interventions to more complex elements of ongoing healthcare and support and broader topics such as migration public health, migration policy and health systems. Beyond biomedical frameworks, it draws on socio-ecological models to inform assessments and integrated models of care to improve health and health equity. Set out in three comprehensive sections: public health theory (Part 1), applied public health (Part 2), and clinical approaches (Part 3), this book draws on multiple disciplines and insights from humanitarians, academics, policy experts, and clinicians from diverse contexts, with expertise in forced migration, to create an accessible reference tool to inform healthcare professionals’ interactions with forcibly displaced individuals and populations in all contexts for both high and low resource countries. Apart from providing information across the spectrum of health issues, clinical specialties and global contexts, it discusses associated areas, including human rights and law, public health, medical anthropology and cultural awareness. Key Features: Bridges the gap between existing academic literature on refugee health and guidelines for health management in humanitarian emergencies Helps to develop an integrated approach to healthcare provision, allowing healthcare professionals and humanitarians to adapt their specialist knowledge for use in forced migration contexts and with refugees. Recognizes the complex and interconnected needs in displacement scenarios and identifies holistic and systems-based approaches. Covers public health theory, applied public health and clinical aspects of forced migration.Biological and Pharmacological Properties of the Genus Moringa
By J. Basilio Heredia. 2022
There is an increasing interest in plants of the Moringa genus used as a source of phytochemicals with biopharmaceutical potential,…
as a functional ingredient in many products and as an additive in poultry feeding stocks. Biological and Pharmacological Properties of the Genus Moringa is the first publication to comprehensively assess the latest research on Moringa studies. This book reviews recent studies covering the botanical, agronomical, genomic, biotechnological, and ethnopharmacological aspects. It presents specialized work in a user-friendly way that will appeal to undergraduates, graduates and researchers primarily in ethnopharmacology, functional foods and with a linkage to veterinary treatments. Key Features: Describes the ethnopharmacological and ethnobotanical use of plants from all Moringa species Presents recent information that will be helpful for the future development of biopharmaceuticals Reviews the phytochemical content from all Moringa species Assesses the potential of all Moringa species as a functional ingredientThe Addiction of Mary Todd Lincoln
By Anne E. Beidler. 2009
Mary Todd Lincoln, wife of the president we have immortalized, has always been difficult for us to understand. She could…
appear poised and brilliant one moment yet rude and ugly the next. Sometimes competent and strong, able to entertain dignitaries from around the world, at other times she appeared dependent and weak. At times she seemed utterly beside herself with sobbing and screaming. Historians have mostly avoided saying very much about Mary Todd Lincoln except in reference to her husband, Abraham. To many it would seem that Mary Todd Lincoln is still an embarrassment in the tragic story of her martyred husband. But Mary Todd Lincoln lived her own tragic story even before Abraham was murdered. She was an addict, addicted to the opiates she needed for her migraine headaches. Seeing Mary Todd Lincoln as an addict helps us understand her and give her the compassion and admiration she deserves. In her time there had been no courageous First Lady like Betty Ford to help people understand the power of addiction. There was no treatment center. In Mary Todd Lincoln's time there were many addicts at all levels of society, as there are now, but it was a more socially acceptable condition for men to have than for women. More importantly, addiction was not very well understood, and it was often mistreated. Because Mary Todd Lincoln's only surviving son, Robert Lincoln, made a great effort to protect his mother and his family from journalists and historians, he intentionally destroyed most of Mary Todd Lincoln's medical records and many of her letters. What he could not destroy, however, is the record of Mary Todd Lincoln's pain and the record of how she behaved while living with this pain. In The Addiction of Mary Todd Lincoln, we can see clearly, for the first time, what Mary Todd Lincoln had to live with and the courage it took for her to carry on.Suspicion: Vaccines, Hesitancy, and the Affective Politics of Protection in Barbados
By Nicole Charles. 2021
In 2014 Barbados introduced a vaccine to prevent certain strains of the human papillomavirus (HPV) and reduce the risk of…
cervical cancer in young women. Despite the disproportionate burden of cervical cancer in the Caribbean, many Afro-Barbadians chose not to immunize their daughters. In Suspicion, Nicole Charles reframes Afro-Barbadian vaccine refusal from a question of hesitancy to one of suspicion. Drawing on ethnographic fieldwork, black feminist theory, transnational feminist studies and science and technology studies, Charles foregrounds Afro-Barbadians' gut feelings and emotions and the lingering trauma of colonial and biopolitical violence. She shows that suspicion, far from being irrational, is a fraught and generative affective orientation grounded in concrete histories of mistrust of government and coercive medical practices foisted on colonized peoples. By contextualizing suspicion within these longer cultural and political histories, Charles troubles traditional narratives of vaccine hesitancy while offering new entry points into discussions on racialized biopolitics, neocolonialism, care, affect, and biomedicine across the Black diaspora.Duke University Press Scholars of Color First Book Award recipientConceptual Biomechanics and Kinesiology
By Animesh Hazari, Arun G. Maiya, Taral V. Nagda. 2021
This book presents essential information on the various concepts of biomechanics and kinesiology applied to human body, also describing in…
depth the understanding of the various physical and mathematical principles applied towards understanding of this science of movement. It tries to simplify this biological movement science by facilitating easy understanding of the various applications of the forces acting on the human body. This book provides a deep insight to the clinical gait analysis and it’s interpretations with graphical outputs, it also covers important topics such as biomechanics of important human joints such as neck, shoulder, spine, hip, knee and ankle with their recent advances. It also includes chapters on biomechanical instrumentation and their interpretation. Another highlight of the book is chapters on biomechanical motion analysis systems used for athletes. This book offers a valuable resource for medical and paramedical students, researchers and clinicians practicing musculoskeletal and manual therapy, aiding researchers gaining insight to human biomechanics.Anatomy for Urologic Surgeons in the Digital Era: Scanning, Modelling and 3D Printing
By Emre Huri, Domenico Veneziano. 2021
This book provides a practical guide in the use of imaging and visualization technologies in urology. It details how output…
from diagnostic systems, can be represented through synthetic, virtual and augmented reality tools, such as holograms and three dimensional (3D) modelling and how they can improve everyday surgical procedures including laparoscopic, robotic-assisted, open, endoscopic along with the latest and most innovative approaches. Anatomy for Urologic Surgeons in the Digital Era: Scanning, Modelling and 3D Printing systematically reviews diagnostic imaging, visualization tools available in urology and is a valuable resource for all practicing and in-training urological surgeons.Access to Medicines and Vaccines: Implementing Flexibilities Under Intellectual Property Law
By Reto M. Hilty, Carlos M. Correa. 2022
This open access book is the outcome of a Global Forum on Innovation, Intellectual Property and Access to Medicines held…
in December 2019 at the Max Plank Instititute in Munich, organised by the South Centre and the Max Plank Institute. The academics and experts from international organisations participating have contributed chapters to this book. The book is for policy makers (in Ministries of Health, Ministries of Trade, Ministries of Foreign Affairs, patent offices), but also relevant for academics (law, trade, public health), on the flexibilities available in the Agreement on Trade Related Aspects of Intellectual Property Rights (TRIPS) of the World Trade Organization to promote access to medicines.Clinical Functional MRI: Presurgical Functional Neuroimaging (Medical Radiology)
By Christoph Stippich. 2022
The third, revised edition of this successful book describes up-to-date preoperative fMRI and complementary advanced imaging methods (DTI, MEG, PET,…
etc.) to diagnose and treat patients with brain tumors and epilepsy. It presents the state of the art fMRI and complementary imaging procedures and discusses practical aspects, imaging and data processing steps, normal and pathological findings, and diagnostic possibilities and limitations. Experts in the field explain relevant information on brain physiology, functional neuroanatomy, and imaging techniques.All chapters of the second edition have been fully updated to reflect the latest developments. Multimodality functional neuroimaging was rewritten by new authors. Further chapters address brain plasticity, and pitfalls, tips, and tricks.Handbook Positive Health in Primary Care: The Dutch Example
By Machteld Huber, Hans Peter Jung, Karolien van den Brekel-Dijkstra. 2022
Increasing numbers of general practitioners are discovering the benefits of working with Positive Health. It helps to talk with patients…
in a different way, with a focus on possibilities rather than on the impossibilities related to a particular health problem. This is good for the patient. And for the general practitioner. But how do we apply Positive Health? This handbook provides useful tools!The book is full of tips, tells the story of how the concept was first developed and gives practical examples. It explains the underlying scientific basis of Positive Health — with a clear emphasis on what is meaningful to patients. And, above all, this book invites you to start working with Positive Health on various levels — in your consulting room, your practice and in the local community. Because cooperation and combined effort are key. You will experience how Positive Health seamlessly fits the core values and challenges of all aspects of primary care. The handbook is intended for all primary care professionals as well as those who are still in training. It describes the Dutch health care system and the experiences related to inspiration, implementation and the anchoring of the Positive Health concept into this system. The publication is indispensable for anyone who wants to provide meaningful primary care using the Positive Health concept. ‘When I heard about Positive Health and the spider web, I felt that it gave us a much wanted tool to empower our patients and the community.’ Elínborg Bárðardóttir, general practitioner & programme director primary care training, Primary Healthcare in IcelandMuch more than a "how-to" exercise book, the complete guide to walking is an interactive handbook that can make the…
difference for millions of Americans who struggle with weight loss, health and dietary concerns, stress, and chronic fatigue. Here, Mark Fenton, the nation's foremost expert on walking, offers dozens of realistic solutions to help readers overcome their individual barriers to regular daily activity. As editor at Walking magazine and coach of beginners and world-class athletes alike, Fenton promises to transform readers of all ages from couch potato to athlete in less than one year with this responsible, motivational, and enjoyable prescription to a healthier life.Breaking Out: A Woman's Guide to Coping with Acne at Any Age
By Lydia Preston. 2004
An essential and comprehensive guide to acne for women of all ages Acne is no longer just a teenage affliction.…
In fact, dermatologists often refer to it as a woman's disease, and drugstore shelves are filled with acne products specifically geared toward adult women. But how do you choose from the overwhelming selection of treatments? Which products are appropriate to use as you grow older, become pregnant, or enter menopause? How can you work with a dermatologist to get the most out of prescription acne medications? Lydia Preston answers all of these questions and more, with up-to-date information drawn from her years of reporting on dermatology, as well as her own long personal experience with acne. In Breaking Out, she shares the wisdom of dozens of doctors and scientists who have devoted their careers to studying and treating acne, including: Guidelines for buying and using over-the-counter products Treatment for acne scars Emergency acne remedies and camouflage tips Alternative treatments, including herbal remedies, acupuncture, dietary approaches, and ways to unlock the mind-skin connection No one has to live with acne or its consequences. Breaking Out is an invaluable guide to understanding and combating acne that women of all ages can turn to with confidence.Handbook of the Cerebellum and Cerebellar Disorders
By Noriyuki Koibuchi, Donna L. Gruol, Jeremy D. Schmahmann, Roy V. Sillitoe, Mario U. Manto. 2022
Our knowledge of cerebellar functions and cerebellar disorders, called ataxias, is increasing considerably. Studies of the cerebellum are now a…
central focus in neuroscience. During the last four decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and biology of mental processes, behavioral symptoms, and emotion. It is now accepted that the cerebellum acts as a cognitive operator in learning, perception, and attention. Moreover, major improvements in our assessment of in vivo cerebellar architecture using imaging techniques have occurred. A typical example is the accurate description of cerebellar anatomy during fetal development with MRI, a progress which has direct impacts on patient care. These advances have been associated with discoveries of new clinical disorders, in particular in the field of genetic ataxias. More than 20 new genes have been identified these last 10 years. Only for dominant ataxias, more than 30 diseases have now been unravelled. The number of ataxic disorders will increase with aging, the cerebellum being the structure of the brain with the most important loss of neurons with age. More than 300 different cerebellar disorders are encountered during daily practice, but we are missing a single source of information explaining their pathogenesis. Despite the immense amount of knowledge acquired about the cerebellar circuitry these last years, a large book covering the neuroscience of the cerebellum is missing. The goal of this endeavour is to bring up to date information relevant for basic science and also for clinical activities. To reach this goal, the most renowned authors are gathered in a unique and in-depth book with a format of a handbook. We emphasize the connections between molecular findings, imaging features, behavioural/neuropsychological aspects, and clinical implications.Artificial Intelligence in Drug Design (Methods in Molecular Biology #2390)
By Alexander Heifetz. 2022
This volume looks at applications of artificial intelligence (AI), machine learning (ML), and deep learning (DL) in drug design. The…
chapters in this book describe how AI/ML/DL approaches can be applied to accelerate and revolutionize traditional drug design approaches such as: structure- and ligand-based, augmented and multi-objective de novo drug design, SAR and big data analysis, prediction of binding/activity, ADMET, pharmacokinetics and drug-target residence time, precision medicine and selection of favorable chemical synthetic routes. How broadly are these approaches applied and where do they maximally impact productivity today and potentially in the near future. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary software and tools, step-by-step, readily reproducible modeling protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and unique, Artificial Intelligence in Drug Design is a valuable resource for structural and molecular biologists, computational and medicinal chemists, pharmacologists and drug designers.Contactless Healthcare Facilitation and Commodity Delivery Management During COVID 19 Pandemic (Advanced Technologies and Societal Change)
By Stefan Mozar, Mousmi Ajay Chaurasia. 2022
This book offers concepts related to communication engineering principles to fight the current Covid situation, by developing contactless need-based solutions.…
COVID-19, a global pandemic makes us rethink how governments, organizations, and societies around the world can work with minimum or without physical contact. Technologies like artificial intelligence and big data are playing an essential role in responding to the COVID-19 pandemic. This book is a combination of chapters related to imaging and detective technologies used by the experts to fight the COVID-19 pandemic and a combination of interesting content covering the need of hour solutions generated through cutting edge technologies. In the absence of a proper medicine or vaccine, it is quite evident that nutrition plays an important role in the quick recovery of covid patients which must be very carefully planned with proper diagnostics. Data analysis and X-Ray/CT Image analysis by next-generation techniques like deep sensing, machine learning is interesting and useful for research and applied healthcare professionals. Research findings with a focus on diagnostics and reports generated through important data analysis in the book are quite useful and can be referred to by researchers and professionals working in the area of cutting-edge technologies against COVID 19.