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Vlad the Impaler: The Real Count Dracula
By Enid A. Goldberg, Norman Itzkowitz. 2007
Loyalty meant nothing to Vlad Dracula, a Transylvanian prince who'd sacrifice anything to stay in power. He ruled with a…
thirst for blood so terrible that the most famous vampire in literature was named after him.Henry the Young King, 1155-1183
By Matthew Strickland. 2016
This first modern study of Henry the Young King, eldest son of Henry II but the least known Plantagenet monarch,…
explores the brief but eventful life of the only English ruler after the Norman Conquest to be created co-ruler in his father's lifetime. Crowned at fifteen to secure an undisputed succession, Henry played a central role in the politics of Henry II's great empire and was hailed as the embodiment of chivalry. Yet, consistently denied direct rule, the Young King was provoked first into heading a major rebellion against his father, then to waging a bitter war against his brother Richard for control of Aquitaine, dying before reaching the age of thirty having never assumed actual power. In this remarkable history, Matthew Strickland provides a richly colored portrait of an all-but-forgotten royal figure tutored by Thomas Becket, trained in arms by the great knight William Marshal, and incited to rebellion by his mother Eleanor of Aquitaine, while using his career to explore the nature of kingship, succession, dynastic politics, and rebellion in twelfth-century England and France.The Secret File of the Duke of Windsor
By Michael Bloch. 1988
In this brilliant and authoritative work, based on their private correspondence and papers, Michael Bloch describes the feud which developed…
between the Duke of Windsor and the British royal establishment after the Abdication, the humiliations which were suffered by the ex-King and his wife, and the plots to ensure that they remained in exile.Darling Georgie: The Engima of George V
By Dennis Friedman. 1998
Eminent psychiatrist Dennis Friedman turns his acute gaze on our present Queen Elizabeth's grandfather, King George V (1885-1936), to reveal…
the man behind the monarch. Taking as his starting point the widely held belief that the personality and behavior of parents and grandparents have a powerful influence on the children and grandchildren--and even great-grandchildren--Dr. Friedman's insightful biography contains new evidence. It suggests an emotional inheritance partly derived from his father Edward VII's psychologically damaging upbringing at the hands of Queen Victoria that he was to pass on to his own children. In the case of George, a suffocating relationship with his mother, compounded by the absence and neglect of his father, caused him as a child to suffer extreme separation anxiety, which was reinforced by his being sent away to boarding school at the age of 11, where he was bullied by other victims of similar parenting. His often unhappy time in the Navy and later sexual development is also scrutinized, as are his years on the throne. History depicts George V as a model husband, a near-perfect father, and a self-confident monarch. Dr. Friedman's study of his personal life reveals a quite different man whose legacy is still evident in today's royals.Treatment of Thyroid Tumor
By Hitoshi Noguchi, Takahiro Okamoto, Yasuhiro Ito, Hiroshi Takami, Akira Yoshida. 2012
Creating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and…
then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have established positions in clinical practice in North America and in Western European countries. In Japan, however, where radioisotope facilities are of limited availability, treatment plans for differentiated thyroid cancer differ considerably from those of America and Europe, and the associated clinical guidelines need modification before they can be adopted. In addition, although thyroid tumor is a common disease in endocrine practice, its management can differ even among specialists. Thus, a Japanese clinical guideline for the treatment of thyroid tumor was desired by many clinicians. As a combination of evidence-based and consensus-based guidelines for the treatment of thyroid tumor, this book offers alternatives to conventional approaches in the West. Ultimately, the authors hope the guideline will lead to the best possible treatment for patients all over the world in the not-distant future.Inheritance: A Psychological History of the Royal Family
By Dennis Friedman. 2014
In exploring Royal dynamics, Inheritance sheds light on problems found in any familyOn its first publication in the 1990s, Dennis…
Friedman's Inheritance caused a furor in England as he traced the many problems of the Royal family as it was then back to Queen Victoria's nursery, unveiling a host of psychodramas played out against a privileged background of English palaces and Scottish castles. In a post-Diana age, the arrival of a new Prince George to the seemingly stable and blissfully happy William and Kate seems to refute Fiedman's thesis--but what of the notoriously wayward Prince Harry? Many questions are raised in this book addressing the complex and turbulent royal relationships, perhaps the most fundamental being the rigid and traditional royal upbringing which still awaits the baby prince. As the royal line is followed down the generations no direct descendent is overlooked and no issue is sidestepped.The Playboy Princes: The Apprentice Years of Edward VII and VIII
By Peter Beer. 2014
A fascinating dual biography proves that controversial Royal Family members are not necessarily only a feature of late 20th- or…
21st-century lifeEdward VII (1841-1910) and his grandson Edward VIII (1894-1972) were born in different eras, but it is illuminating to compare the early and middle years of the two Princes of Wales as kings in waiting and discover how their youth informed their years on the British throne. The privileges of rank aside, they were heirs to an unenviable role, and this study presents a unique portrait of strained apprenticeships for which there was no satisfactory precedent. Theirs was an upbringing dictated by dogmatic prescription and the heavy weight of obligation. As they pursued their lives according to their distinct personalities, they were never relieved of parental strictures, especially with regard to Queen Victoria and her eldest son, who filled the void with shallow interests, a profligate style of living, and the delights of Parisian nightlife. Inevitably the two princes were consigned to filling much of their time with insubstantial engagements not best suited to their characters and which reveal a common vulnerability. In the case of the future Edward VIII, he took a jaundiced view of matters of state and preferred dance floors, riding to hounds, and the ministrations of lovers. This book is the story of the heirs' progress that provides often unexpected perspectives on two public figures better known through the history of their respective reigns. For readers in this era, the similar position of Prince Charles ensures that this survey is a timely as well as a surprisingly entertaining read.The Gothic King: A Biography of Henry III
By John Paul Davis. 2013
The first biography in many years of Henry IIIThe son and successor of Bad King John, Henry III reigned for…
56 years from 1216, the first child king in England for 200 years. England went on to prosper during his reign and his greatest monument is Westminster Abbey, which he made the seat of his government--indeed, Henry III was the first English King to call a parliament. Though often overlooked by historians, Henry III was a unique figure coming out of a chivalric yet Gothic era: a compulsive builder of daunting castles and epic sepulchres; a powerful, unyielding monarch who faced down the De Montfort rebellion and waged war with Wales and France; and, much more than his father, Henry was the king who really hammered out the terms of the Magna Carta with the barons. John Paul Davis brings all his forensic skills and insights to the grand story of the Gothic King in this, the only biography in print of a most remarkable monarch.Sophia of Hanover: From Winter Princess to Heiress of Great Britain, 1630–1714
By J N Duggan. 2010
The detailed memoirs and letters of a gifted and prolific chronicler provide an insider's view of life for the top…
echelons of society in the 16th century Sophia, Electress of Hanover (1630-1714), granddaughter of James I, and mother of George I, is best remembered as the link between the Houses of Stuart and Hanover. A true European, Sophia spoke English, French, German, Dutch, and Italian fluently, and was open-minded and intellectually curious. Her writings cover an astonishing variety of subjects: religion, philosophy, international gossip, household hints, politics, and the details of her family life.Everything You Need to Know to Manage Type 2 Diabetes: Simple Steps for Surviving and Thriving with the Low GI Plan
By Kaye Foster-Powell, Jennie Brand-Miller, Stephen Colagiuri, Alan Barclay. 2007
A practical, easy-to-use guide to help you manage type 2 diabetes or prediabetes If you are one of the millions…
of people living with diabetes or prediabetes, you may feel like you're inundated with information on how to manage your condition. The good news is that we now know a lot more about managing diabetes or reducing your risk of developing it--and here, the world's foremost glycemic index experts share their wisdom. Rather than blind you with science or swamp you with facts, Everything You Need to Know to Manage Type 2 Diabetes sets out clearly and simply what you need to eat and do to help you: Reduce your risk of developing diabetes Improve your insulin sensitivity and your cardiovascular health Keep your blood glucose levels, blood pressure, and blood fats under control Reduce your body fat and maintain a healthy body With tips and strategies for working with your doctor, the most recent info on medications, and guidance on the best foods to eat (at home or at a restaurant), Everything You Need to Know to Manage Type 2 Diabetes offers uncomplicated, straightforward advice to help you survive--and thrive.Cleopatra: Cleopatra (Phoenix Press Ser.)
By Michael Grant. 2000
Cleopatra, Queen of Egypt, was also a scholar, murderer, lover of Julius Caesar and Mark Antony and one of the…
most remarkable women in history.The distinguished historian and classicist Michael Grant confirms that her reputation as a temptress was well-founded. However, by unravelling the sources behind the tangle of myth, gossip and invention he shows that the popular image of a wayward woman opting for a life of sensuous luxury and neglecting her affairs of state is far from the truth.A brilliant linguist and the first of her Greek-speaking dynasty who learned Egyptian, she was reputed to be the author of treatises on agriculture, make-up and alchemy. Her love affairs were carefully calculated to further her plans to restore her empire to its former greatness and she was a ruthless foe to all who stood in her way.But dead on her golden couch in the palace at Alexandria her life seemed to have ended in failure; her dreams of empire shattered; her lover Mark Antony a suicide himself and she a prisoner of her conqueror Octavian.An unforgettable portrait of an extraordinary queen and her stormy life.Low GI Diet: Managing Type 2 Diabetes
By Kaye Foster-Powell, Jennie Brand-Miller. 2014
The revised edition of the essential handbook on how to reduce the health risks posed by Type 2 Diabetes -…
from the team behind the internationally bestselling Low GI series. Are you living with type 2 diabetes or pre-diabetes and trying to manage your condition? In Australia and New Zealand alone diabetes and pre-diabetes affect 1 in 4 people. Every day nearly 300 people, including children, develop type 2 diabetes and for every person diagnosed with diabetes there's someone else with undiagnosed diabetes. The good news is that we now know a lot more about managing diabetes or reducing your risk of developing it. Low GI Diet: Managing Type 2 Diabetes cuts through the confusion of conflicting advice and sets out clearly and simply what you need to eat and do to help you: reduce your risk of developing diabetes; improve your cardiovascular health; keep your blood glucose levels, blood pressure and blood fats under control; and maintain a healthy body. This book is a practical guide to help you manage your diabetes or pre-diabetes with diet and lifestyle from the highly qualified, specialist team of authors led by world Low GI authority Professor Jennie Brand-Miller. It shows what you can do for yourself - and why. Best of all, this information is good advice for everyone in your family, not just you.Diabetes and Cardiovascular Disease
By Francesco Paneni, Francesco Cosentino. 2015
This book provides a practical hands-on approach to the management of patients with diabetes and cardiovascular disease, with original and…
up-to-date coverage of a variety of aspects of emerging clinical importance. Practical advice is offered on diagnosis, risk stratification, management of cardiovascular risk factors and available drug therapies. Appropriate myocardial revascularization strategies are explained and the current state of knowledge is documented regarding target-led multifactorial treatment and the management of acute coronary syndromes, heart failure, and cerebrovascular disease. New algorithms for diagnosis and treatment are presented and to ensure ease of reference each chapter includes a box with practical recommendations as well as informative color illustrations and tables. The handbook will be of value for all cardiologists and diabetologists and will be especially helpful for young cardiologists, who are ever more frequently confronted by patients with diabetes and cardiovascular disease.Genetic Damage in Human Spermatozoa
By Monica Muratori, Elisabetta Baldi. 2014
There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate…
during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.Aristotle on Political Community
By David J. Riesbeck. 2016
Aristotle's claims that 'man is a political animal' and that political community 'exists for the sake of living well' have…
frequently been celebrated by thinkers of divergent political persuasions. The details of his political philosophy, however, have often been regarded as outmoded, contradictory, or pernicious. This book takes on the major problems that arise in attempting to understand how the central pieces of Aristotle's political thought fit together: can a conception of politics that seems fundamentally inclusive and egalitarian be reconciled with a vision of justice that seems uncompromisingly hierarchical and authoritarian? Riesbeck argues that Aristotle's ideas about the distinctive nature and value of political community, political authority, and political participation are coherent and consistent with his aristocratic standards of justice. The result is a theory that, while not free of problems, remains a potentially fruitful resource for contemporary thinking about the persistent problems of political life.Thymic Development and Selection of T Lymphocytes
By Thomas Boehm, Yousuke Takahama. 2014
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place.…
Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.The Red Prince: The Secret Lives of a Habsburg Archduke
By Timothy Snyder. 2008
Wilhelm Von Habsburg wore the uniform of the Austrian officer, the court regalia of a Habsburg archduke, the simple suit…
of a Parisian exile, the collar of the Order of the Golden Fleece, and, every so often, a dress. He could handle a saber, a pistol, a rudder, or a golf club; he handled women by necessity and men for pleasure. He spoke the Italian of his archduchess mother, the German of his archduke father, the English of his British royal friends, the Polish of the country his father wished to rule, and the Ukrainian of the land Wilhelm wished to rule himself. In this exhilarating narrative history, prize-winning historian Timothy D. Snyder offers an indelible portrait of an aristocrat whose life personifies the wrenching upheavals of the first half of the twentieth century, as the rule of empire gave way to the new politics of nationalism. Coming of age during the First World War, Wilhelm repudiated his family to fight alongside Ukrainian peasants in hopes that he would become their king. When this dream collapsed he became, by turns, an ally of German imperialists, a notorious French lover, an angry Austrian monarchist, a calm opponent of Hitler, and a British spy against Stalin. Played out in Europe’s glittering capitals and bloody battlefields, in extravagant ski resorts and dank prison cells, The Red Prince captures an extraordinary moment in the history of Europe, in which the old order of the past was giving way to an undefined future-and in which everything, including identity itself, seemed up for grabs.The Plantagenets: The Kings That Made Britain
By Derek Wilson. 2014
Plantagenet is the name given to the English royal house descended from the union of Queen Matilda of England and…
her second husband Geoffrey of Anjou. The name derived from Geoffrey's nickname, which came from the sprig of broom (planta genet) which he wore in his hat. The Plantagenets ruled England for more than three hundred years, from the accession of reign of the dynasty's founder, Matilda and Geoffrey's son, Henry II, in 1154, to the death of the last Plantagenet, Richard III, at the Battle of Bosworth in 1485. The Plantagenets: The Kings That Made Britain is a compelling, year-by-year chronology of a tumultuous and critical period in the development of the English nation. Each year is covered by a concise, informative and accessible narrative, amplified by extensive quotation from contemporary sources and accompanied by generously captioned and stunning images of the period-including illuminations, portraits, maps, royal seals, tapestries and other artifacts. Authoritative, informative and sumptuous, and compiled by a scholar who is steeped in knowledge of the period, The Plantagenets: The Kings That Made Britain brings a critical era of English history dramatically and vividly to life. It is the perfect gift book for anyone with a love of, or fascination for, medieval English history.Obesity and Breast Cancer
By Kristy A. Brown, Evan R. Simpson. 2014
Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been…
shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are oestrogen-dependent. Since the ovaries no longer produce oestrogens after menopause, and that circulating levels are negligible, it is evident that it is the oestrogens produced locally within the breast adipose that are responsible for the increased growth of breast cancer cells. Aromatase is the enzyme that converts androgens into oestrogens and its regulation is dependent on the activity of a number of tissue-specific promoters. Targeting oestrogen biosynthesis in obesity may be useful for the prevention of breast cancer. Aromatase inhibitors are efficacious at treating postmenopausal breast cancer and recent studies suggest that they may also be useful in the prevention setting. However, these compounds inhibit the catalytic activity of aromatase and as a consequence lead to a number of undesirable side-effects, including arthralgia and possible cognitive defects due to inhibition of aromatase in the bone and brain, respectively. Novel therapies, such as those employed to treat obesity-associated disease, including anti-diabetics, may prove successful at inhibiting aromatase specifically within the breast. This SpringerBrief will explore all of these issues in depth and the authors are in a unique position to write about this topic, having extensive experience in the field of aromatase research.The Cleveland Clinic Manual of Dynamic Endocrine Testing
By Ahmet Bahadir Ergin, A. Laurence Kennedy, Manjula K. Gupta, Amir H. Hamrahian. 2015
Developed via a peer review process that included 25 experienced endocrinologists and utilizing the best current evidence, The Cleveland Clinic…
has created a practical set of protocols for over 25 commonly used dynamic endocrine tests. The cornerstone of clinical endocrinology, these evidence-based protocols play an important role in clinical decision-making and are important element of billing and compliance with high quality standards. Included here are various tests for pituitary and adrenal disorders, thyroid disorders, and glucose metabolism and pancreatic disorders, presented systematically with indications, preparation, materials needed, precautions, procedure, interpretation, and caveats. Filling the gap left by a lack of national guidelines, The Cleveland Clinic Manual of Dynamic Endocrine Testing is an up-to-date practical guide for endocrinologists, nurses, and their staff, inside or outside of the US, who need to perform and interpret dynamic endocrine testing in their everyday practice, as well as medical students, residents and fellows who have interest in endocrinology.