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Showing 121 - 140 of 1820 items
By I. Howard Fine, Jorge L. Alió y Sanz. 2010
Many ophthalmologists are in the transition from the traditional cataract surgery technique to the new minimally incision cataract surgery (MICS)…
technique. They are in the need of updated information on how to make this transition smoothly. In this book, world-renowned opinion leaders present up-to-date information on the new and fast-developing trends in cataract surgery. It reflects the state of the art of microincisional cataract surgery with the concept of minimizing incision. It offers all necessary information on the new technology as well as on the surgical technique. Further, it demonstrates how to handle difficult cataract cases as well as new intraocular lenses.By Craig Roberts, Sabra L. Klein. 2010
Why sex matters Among human and nonhuman animals, the prevalence and intensity of infection typically is higher in males than…
females and may reflect differences in exposure as well as susceptibility to pathogens. Elevated immunity among females is a double-edged sword in which it is beneficial against infectious diseases but is detrimental in terms of increased development of autoimmune diseases. The present book critically reviews the evolutionary origin and the functional mechanisms responsible for sexual dimorphism in response to infection. It emphasizes the value of examining responses in both males and females to improve our understanding about host-pathogen interactions in both sexes. The contributors are experts in their specific disciplines which range from microbiology and immunology to genetics, pathology, and evolutionary biology. The book aims at bringing insight to the treatment and management of infectious diseases; it delineates areas where knowledge is lacking and highlights future avenues of research.By Ashok Agarwal, Armand Zini. 2011
Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk…
of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men. Written by leading, internationally renowned clinicians and basic scientists with expertise in sperm DNA, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction provides readers with a thoughtful and comprehensive review of the biological and clinical significance of sperm DNA damage. The work covers the fundamental principles of sperm chromatin architecture and function, the proposed modes of DNA damage and repair, the tests of sperm DNA damage, the clinical aspects of DNA damage and the impact of DNA damage on reproductive outcome. Unlike any other title on the topic, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction is an invaluable addition to the literature and will serve as an indispensable resource for basic scientists with an interest in sperm biology and for urologists, gynecologists, reproductive endocrinologists, and embryologists working in the field of infertility.By Dominique Raynaud. 2017
This book clarifies the interrelationship between optics, vision and perspective before the Classical Age, examining binocularity in particular. The author…
shows how binocular vision was one of the key juncture points between the three concepts and readers will see how important it is to understand the approach that scholars once took. In the Middle Ages and the Renaissance, the concept of Perspectiva - the Latin word for optics - encompassed many areas of enquiry that had been viewed since antiquity as interconnected, but which afterwards were separated: optics was incorporated into the field of physics (i. e. , physical and geometrical optics), vision came to be regarded as the sum of various psycho-physiological mechanisms involved in the way the eye operates (i. e. , physiological optics and psychology of vision) and the word 'perspective' was reserved for the mathematical representation of the external world (i. e. , linear perspective). The author shows how this division, which emerged as a result of the spread of the sciences in classical Europe, turns out to be an anachronism if we confront certain facts from the immediately preceding periods. It is essential to take into account the way medieval scholars posed the problem - which included all facets of the Latin word perspectiva - when exploring the events of this period. This book will appeal to a broad readership, from philosophers and historians of science, to those working in geometry, optics, ophthalmology and architecture.By Sam Dagogo-Jack. 2017
Adopting a truly global perspective and a practical approach to diabetes--including pathophysiology, genetics, regional peculiarities, management, prevention and best practices--this…
book is an excellent resource for clinicians and policy-makers working with patients in more austere settings. The global prevalence of diabetes is estimated to increase from 422 million in 2014 to 592 million in 2035. Sadly, low- and middle-economy countries are projected to experience the steepest increase, but even in developed economies, vulnerable demographic subgroups manifest disparities in diabetes prevalence, quality of care, and outcomes. This book extends coverage to those underserved and minority communities in the developed world. In a consistent chapter format, it discusses classification, pathophysiology, genomics, diagnosis, prevention and management of diabetes in economically challenged regions as well as underserved populations in affluent nations. Suggestions regarding future directions in the organization of diabetes care delivery, prevention and research priorities are also provided. The detailed identification of barriers to optimal care and the practical approach to the management and prevention of diabetes make Diabetes Mellitus in Developing Countries and Underserved Communities a valuable resource for clinicians, researchers and health policy leaders.By Aria Baniahmad. 2002
A panel of outstanding investigators surveys and explains the major cutting-edge methods used in thryroid receptor (TR) research and explains…
their practical experimental details. Described in step-by-step detail to ensure robust experimental results, the techniques presented cover a wide variety of key areas, including TR in development and knockout (mouse and Xenopus), transcriptional regulation by TRs in both cell-free systems and in living cells, and TR mutant analysis of patients. Additional methods provide powerful tools for the isolation of TR-regulated protein complexes, for studying the oncogene v-Erba in blood cell differentiation, and for target gene analysis in the brain. Microarray chip methods are also presented for analyzing the organs of transgenic mice to identify target genes in the liver.By J. Fernando Arévalo. 2001
This text presents current information on retinal and choroidal manifestations of systemic diseases from leading experts in the field. Topics…
include retinal and choroidal manifestations of AIDS, pediatric diseases, toxicity of systemic drugs, diseases of the gastrointestinal tract, diffuse unilateral subacute neuroretinitis (DUSN), viral and fungal diseases, sarcoidosis, Behçet's disease, carotid artery and renal diseases, changes related to pregnancy, intraocular lymphoma, and more. Their knowledge and experience will assist ophthalmologists, retina specialists, uveitis and ocular oncology specialists, and general physicians approach a level of knowledge about retinal and choroidal manifestations of systemic diseases to benefit patients in everyday clinical practice.By Sally Radovick, Margaret H. Macgillivray. 2013
A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded…
Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes new topics being seen more commonly in pediatric endocrinology practices related to obesity and type 2 diabetes mellitus and lipid disorders. Each chapter contains an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. Invaluable tables summarize the critical factors in etiology, clinical presentation, diagnosis, and therapeutic dosages. Pediatric Endocrinology: A Practical Clinical Guide, Second Edition, is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents.By Shimon Efrat. 2010
Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews…
the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and addresses tissue engineering and ways for cell protection from recurring autoimmunity and graft rejection. Stem Cell Therapy for Diabetes provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes.By Philip B. Gorelick, Venkatesh Aiyagari. 2011
This timely volume addresses the intimate pathophysiologic relationship between hypertension and cardiovascular disease. Hypertension is one of the most important…
global public health challenges, and its relationship to stroke and other catastrophic cerebrovascular diseases is an area of growing understanding. In this outstanding book, the editors and authors clearly and concisely synthesize our developing knowledge and place epidemiologic and physiologic information into a practical clinical context. Comprehensive chapters present the evidence supporting strategies for stroke prevention and care, including blood pressure lowering therapies, anti-coagulation, and management of other cerebrovascular risk factors. In addition to prescriptive measures for first stroke prevention, the book illuminates current regimens for care immediately after acute stroke and for the prevention of recurrent stroke. A unique section is dedicated to the exploration of the interaction between elevated blood pressure and brain function and cognition. The concluding chapter provides a resource towards optimizing the organization of stroke care. Hypertension and Stroke is of great utility for specialists in neurology and cardiovascular medicine and a valuable practical resource for all physicians caring for older adults and hypertensive patients.By Warren R. Heymann. 2008
The spectrum of the cutaneous manifestations of thyroid disease includes cutaneous metastases from thyroid malignancies and thryoglossal duct cysts, nonspecific…
alterations of the skin, hair, and nails reflecting both the hyperthyroid and hypothyroid states, and the multiple associations of thyroid disease with other cutaneous and systemic diseases. Internists, family practitioners, pediatricians, geriatricians, and dermatologists address these issues on a daily basis: When is it appropriate to evaluate a patient for thyroid disease? How should the patients be evaluated? How often should testing be performed? Should other family members be screened for thyroid disease? The purpose of The Thyroid in Dermatology is to raise awareness of the vast spectrum of thyroid-skin interactions, and to provide a framework for the appropriate diagnosis and management of these diseases.By Leopold Schmetterer, Jeffrey Kiel. 2012
Adequate blood supply to the eye is an important prerequisite for normal visual function. Over the past 40 years our…
knowledge of ocular blood flow regulation has improved significantly. This reader-friendly textbook provides a comprehensive overview of the current knowledge of ocular blood flow. Lavishly illustrated, it evaluates the wide array of methods that have been used to measure ocular blood flow. Furthermore, it not only offers the reader an evidence-based summary of the physiological and pharmacological properties of ocular blood flow regulation, but also demonstrates the ocular blood flow abnormalities in different vascular diseases. This book will enhance the understanding of all who are interested in learning more about ocular blood flow in health and disease.By Carolyn Heller. 2012
Moon Spotlight Georgian Bay & Cottage Country is a 70-page compact guide covering the best of south-central Ontario. Professional travel…
writer Carolyn B. Heller offers her firsthand advice on must-see attractions, as well as maps with sightseeing highlights, so you can make the most of your time. This lightweight guide is packed with recommendations on entertainment, shopping, recreation, accommodations, food, and transportation, making navigating this strikingly beautiful region of Ontario uncomplicated and enjoyable.By Bernhard H.F. Weber, Thomas Langmann. 2013
Over the past decades, knowledge about the cellular and molecular basis underlying the visual process has remarkably increased. In Retinal…
Degeneration: Methods and Protocols, expert researchers in the field provide a guide of relevant and state-of-the-art methods for studying retinal homeostasis and disease. These include methods and techniques for addressing cell culture systems and animal models of disease, their generation, their phenotypic and molecular characterization as well as their use in therapeutic approaches to the retina. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Retinal Degeneration: Methods and Protocols aids scientists in continuing to study the cutting-edge techniques of retinal cell biology in health and disease.By Harshad Keval. 2016
This book explores the often contentious relationship between health, concepts of race and ethnicity, and the impact on South Asian…
groups. Using medical sociological and anthropological perspectives, it excavates racialised constructions of diabetes 'risk' within discourses, and highlights the contrasting counter narratives in people's accounts of their everyday lives. By identifying a number of components to the discursive, racialised construction of 'risky' South Asian bodies, this book problematises taken for granted understandings of culture, lifestyle and genetic risk. The mobilisation of these mechanisms in health science and interventions result in a racialising gaze, directed at groups already experiencing historically embedded race-related issues. The book situates these constructions of risk against the emergent, fluid and dynamic counter narratives to risk constructions. The new found momentum in genetic science is also critiqued in its formulation of racial-genetic risk, especially in the case of diabetes in South Asian groups, and is identified as perpetuating a series of racializing processes.By Jennifer S. Weizer, Sharon Fekrat. 2006
A concise, easy-to-understand reference book, All about Your Eyes tells you what you need to know to care for your…
eyes and what to expect from your eye doctor.In this reliable guide, leading eye care experts:--explain how healthy eyes work--describe various eye diseases, including pink eye, cataract, glaucoma, age-related macular degeneration, and diabetic retinopathy--provide up-to-date information on eye surgery, including refractive, laser, and cosmeticFor each eye problem, the authors describe in simple, straightforward language--what it is--the symptoms--what, if anything, you can do to prevent it--when to call the doctor--the treatment--the likelihood of recoveryAll about Your Eyes includes a glossary of technical terms and, following each entry, links to web sites where further information may be found.Despite a plethora of scientific literature devoted to vision research and the trend toward integrative research the borders between…
disciplines remain a practical difficulty To address this problem this book provides a systematic and comprehensive overview of vision from various perspectives ranging from neuroscience to cognition and from computational principles to engineering developments It is written by leading international researchers in the field with an emphasis on linking multiple disciplines and the impact such synergy can lead to in terms of both scientific breakthroughs and technology innovations It is aimed at active researchers and interested scientists and engineers in related fieldsBy Christian A Koch, George P Chrousos. 2013
The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions…
being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of hypertension. In Endocrine Hypertension, a renowned panel of experts provides a comprehensive, state-of-the-art overview of this disorder, discussing when to assign an endocrine cause in one of many conditions that may present with hypertension. The first part of Endocrine Hypertension is dedicated to adrenal causes. The second part of the volume concerns potential nonadrenal causes of hypertension, such as growth hormone excess or deficiency, primary hyperparathyroidism, vitamin D deficiency, testosterone deficiency, insulin resistance, obesity-associated hypertension, and the role of central mineralocorticoid receptors and cardiovascular disease. An important contribution to the literature, Endocrine Hypertension is an indispensable reference not only for endocrinologists, diabetologists, and adrenal investigators, but also for translational scientists and clinicians from cardiology, internal medicine, pediatrics, family medicine, geriatrics, urology, and reproductive medicine / gynecology.By Jianhui Hu, Peter Glick, James R. Broyles, Yee-Wei Lim. 2012
Cataracts cause about half of all cases of blindness worldwide, largely in developing countries. HelpMeSee Inc. is developing a simulator-based…
method for rapid cataract surgical training that RAND researchers determined could significantly help to close the backlog of cataract cases, expected to be 32 million globally by 2020. For this to occur, challenges in the areas of outreach, quality monitoring, and public acceptance must be met.By Ashraf Khan. 2009
Surgical pathology is the cornerstone in the management of neoplastic disorders. Written for the practicing surgical pathologist in mind, Surgical…
Pathology of Endocrine and Neuroendocrine Tumors provides an up-to-date text on surgical pathology of endocrine and neuroendocrine tumors. The text begins with radiological imaging of tumors, followed by a section on fine needle aspiration biopsy. The main section focuses on surgical pathology of endocrine and neuroendocrine tumors. The volume closes with applications of molecular techniques and their potential for the future. Surgical Pathology of Endocrine and Neuroendocrine Tumors is written by a panel of internationally recognized pathologists who are not only experts in their fields, but who also contribute their own valuable insights making this new book an essential resource for practicing general and specialist surgical pathologists and pathologists in training.